Tumours Of Kidney (Patho) Flashcards
Benign tumors of kidney?
Renal papillary adenoma
Renal fibroma(hemartoma)
Angiomyolipoma
Oncocytoma
Malignant tumous of kidney?
Renal cell carcinoma (Grawitz tumor, hypernephroma)
Urothelial carcinoma of renal pelvis
Risk factors of renal cell carcinoma?
Tobacco (most important)
Hypertension
Estrogen therapy
Obesity
Asbestos
Petroleum products
Heavy metals
Risk factors of renal cell carcinoma?
Tobacco (most important)
Hypertension
Estrogen therapy
Obesity
Asbestos
Petroleum products
Heavy metals
Classification of renal cell carcinoma
Clear cell carcinoma (70-80%)
Papillary carcinoma (10-15%)
Chromophobe and renal carcinoma(5%)
Collecting duct carcinoma(1%)
What is the renal disease that occurs in patients with essential hypertension?
Benign nephrosclerosis
Benign nephrosclerosis is caused by?
Hyaline arteriosclerosis
Clinical features of benign nephrosclerosis?
Mild proteinuria
Hematuria(no RBC casts)
Increased risk of developing renal failure in
- blacks
-patient with severe hypertension
-patients with a secondary underlying disease e.g diabetes
The disease that occurs in patients with malignant hypertension?
Accelerated nephrosclerosis
Accelerated nephrosclerosis is caused by?
Hyperplastic arteriosclerosis
Characteristics of accelerated nephrosclerosis
Onion skin lesions
Flea bitten kidneys( pin point hemorrhages on the cortical surface)
Clinical findings of accelerated nephrosclerosis
Bp 210/120 mm Hg
Oliguric acute renal failure
Hypertensive encephalopathy i.e cerebral edema,papillodema, retinopathy, intracerebral hemorrhage
Proteinuria
Hematuria with RBC casts
Renal azotemia with BUN:Cr < 15