UTI, Endocarditis, Meningitis

Question 1

What are the DOC in UTIs

Answer 1

Macrobid, Septra, Fosfomycin

Question 2

What is the dose of Macrobid in uncomplicated cystitis?

Answer 2

100mg BID for 5 days

Question 3

What is the dose of Fosfomycin in uncomplicated cycstitis?

Answer 3

3 grams Q once

Question 4

What is the dose of cipro in uncomplicated cycstitis?

Answer 4

250mg bid for 3 days

Question 5

What is the dose of levofloxacin in uncomplicated cycstitis?

Answer 5

250mg QD for 3 days

Question 6

What is the dose of Cipro in complicated cycstitis?

Answer 6

500mg bid x 5-14 days depending on symptoms

Question 7

What is the dose of levofloxacin in complicated cycstitis?

Answer 7

750mg bid x 5-14 days depending on symptoms

Question 8

What are the DOC for acute pyelonephritis?

Answer 8

Cipro 500mg bid OR Levofloxacin 750mg QD for 5-7 days

Question 9

What is the DOC for accute pyelonephritis if FQ resistance is over 10%?

Answer 9

Ceftriaxone 1 gram IV Q once

Question 10

What is the regimen of choice for a child-adult with meningitis?

Answer 10

Ceftriaxone (2gm IV q 12h) + Vanco (45-60mg/kg/day divided q6-8h) + Ampicillin (2gm Q 4h) + Dexamethasone .15mg/kg Q6h for 2-4 days

Question 11

What is the alternate regimen for a child/adult with meningitis?

Answer 11

Meropenem (2gm q 8h) + Vanco (45-60 mg/kg/day divided q6-8h) + Dexamethasone .15mg/kg q6h x2-4 days

Question 12

What is the penicillin allergic regimen for an adult with meningitis?

Answer 12

Chloramphenicol (12.5mg/kg q6h) + Septra (5mg/kg Q6-8h) + Vanco (45-60mg/kg/day divided q6-8h)

Question 13

What is the regimen of choice for a neonate with meningitis?

Answer 13

Ampicillin (75-100mg/kg IV q6h) + Cefotaxime (50mg/kg q6h)

Question 14

What is the altermate regimen for a neonate with meningitis?

Answer 14

Ampicillin (75-100mg/kg Q6h) + Gentamicin (5-7mg/kg/day)

Question 15

What is the DOC in Hib prophylaxis?

Answer 15

Rifampin 600mg PO Qd x 4 days

Question 16

What is the DOC for N. meningitidis prophylaxis?

Answer 16

Rifampin 600mg po q12h x 4 doses OR Cipro 500mg Q once OR Cefriaxone 250mg IMx1

Question 17

What is the Regimen of choice for endocarditis with Viridans (MIC < .1)? (native valve)

Answer 17

Pen G (12-18M units Q day divided q4h) + Gentamicin (1mg/kg q8h) For 2 weeks

Question 18

What is the Regimen of choice for endocarditis with Viridans (MIC > .1 but < .5)? (native valve)

Answer 18

Pen G (24M units QD divided Q4h) + Gentamicin (1mg/kg Q8h) for 4+2 weeks

Question 19

What is the Regimen of choice for endocarditis with Viridans (MIC > .5)? (Native valve)

Answer 19

Pen G (18-30M units QD q4h) + Gentamicin (1mg/kg q8h) OR Ampicillin (2g q4h) + Gentamicin for 4+4 weeks

Question 20

What is the regimen of choice for endocarditis with HACEK? (native valve)

Answer 20

Ceftriaxone (2gm Q 24h) OR Cipro 500mg PO/ 400mg IV q12h) OR Ampicillin/sulbactam (3gm q6h)

Question 21

What is the DOC for IVDA endocarditis caused by MSSA?

Answer 21

Nafcillin (2gm Q 4h) OR Cefazolin (2gm q8) OR Vanco (15-20mg/kg q8-12h)

Question 22

What is the DOC for IVDA endocarditis caused by MRSA?

Answer 22

Vancomycin (15-20mg/kg q8-12h) OR Daptomycin 6mg/kg Q24h

Question 23

What is the DOC for IDVA endocarditis caused by enterococcus?

Answer 23

Pen G (24M units QD divided q4h) + Gent (1mg/kg q8h) OR Ampicillin (2gm Q4h) + Gent OR Vanco (15-20mg/kg Q8h) + Gent

Question 24

What is the DOC for PVE endocarditis caused by S. epi or MRSA

Answer 24

Vanco (15-20mg/kg/day divided q8h) + Gentamicin (1mg/kg Q8h) + Rifampin (300mg Q8h)

Question 25

What is the DOC for PVE endocarditis caused by MSSA

Answer 25

Nafcillin (2gm Q4h) + Rifampin (300mg Q8h) + gentamicin (1mg/kg q8h)

Question 26

With is the DOC for PVE endocarditis caused by MRSA?

Answer 26

Vancomycin (15-20mg/kg q8h) + Rifampin (300mg q8h) + Gentamicin (1mg/kg q8h)

Question 27

What is the DOC for S. pneumo meningitis prophylaxis?

Answer 27

None recommended