Uterus

Question 1

represents a uterine malformation where the uterus is present as a paired organ when the embryogenetic fusion of the Müllerian ducts fails to occur. As a result, there is a double uterus with two separate cervices, and rarely a double vagina as well

Answer 1

Uterus didelphyls

Question 2

commonly referred to as a “heart-shaped” uterus, is a uterus composed of two “horns” separated by a septum

Answer 2

Bicornuate uterus

Question 3

Premenopausal Hyperplasia Without Atypia, Simple

Answer 3

OCP x 6 cycles

Question 4

Premenopausal Hyperplasia Without Atypia, Complex

Answer 4

MPA 10-20 mg OD x 14d

Question 5

Premenopausal Hyperplasia With Atypia, Desires Pregnancy

Answer 5

MPA x 3 mos
Megestrol acetate
DMPA every 3 mos

Question 6

Premenopausal Hyperplasia With Atypia, No desire Pregnancy

Answer 6

EH +/- BSO

Question 7

Postmenopausal Hyperplasia Without Atypia, Simple

Answer 7

OCP x 6 cycles

Question 8

Postmenopausal Hyperplasia Without Atypia, Complex

Answer 8

MPA 10-20 mg OD x 14d

Question 9

Postmenopausal Hyperplasia With Atypia

Answer 9

EH +/- BSO

Question 10

3rd most common genital tract cancer in the PH

Answer 10

Endometrial Ca

Question 11

Primary Prevention Endometrial CA

Answer 11

OCP

Raloxifene

Question 12

Secondary Prevention Endometrial CA

Answer 12

Annual screening biopsy >35 years old with HNPCC risk

Question 13

Most common type of Endometrial CA

Answer 13

Adenocarcinoma

Question 14

types of Endometrial CA with poor prognosis

Answer 14

Serous

Clear Cell

Question 15

Stage of endometrial cancer: confined to the corpus

Answer 15

1

Question 16

Stage of endometrial cancer: extension to cervix but not beyond uterus

Answer 16

2

Question 17

Stage of endometrial cancer: outside uterus, within pelvis

Answer 17

3

Question 18

Stage of endometrial cancer: invades bladder and/or bowel mucosa +/- distant metastasis

Answer 18

4

Question 19

Most common sarcoma of the uterus

Answer 19

Leiomyosarcoma

Question 20

Pure Sarcoma in the Uterus

Answer 20

Leiomyosarcoma - m/c

Endometrial stromal sarcoma/ adenosarcoma

Question 21

type of cancer that contains two types of cancer cells - carcinoma and sarcoma cells

Answer 21

Carcinosarcoma

Question 22

Uterine sarcoma with an aggressive behavior and poor prognosis

Uterine sarcoma that is confused with lymphoma, leukemia, high-grade endometrial CA

Answer 22

Undifferentiated type of Sarcoma

Question 23

Surgical tx for Leiomyosarcoma

Answer 23

EH

Question 24

Adjuvant for Leiomyosarcoma

Answer 24

Doxorubicin

Question 25

Theory of Endometriosis etiology: most widely accepted

Answer 25

Retrograde Menstruation

Question 26

Theory of Endometriosis etiology: explains the rare and remote sites of endometriosis

Answer 26

Lymphatic and Vascular Mets

Question 27

Theory of Endometriosis etiology: endometrial glands ad stroma are implanted during surgical procedures

Answer 27

Iatrogenic dissemination

Question 28

Theory of Endometriosis etiology: Hyperactive monocytic type macrophages -> growth factor
NK cells decreased toxicity on endometrial cells

Answer 28

Immunologic Changes

Question 29

3 Cardinal histologic features of Endometriosis

Answer 29

Ectopic endometrial glands
Ectopic endometrial stroma
Hemorrhage on adjacent tissues

Question 30

Classic signs and symptoms of Endometriosis

Answer 30

Cyclic pelvic pain

Infertility

Question 31

Fixed retroverted uterus with scarring and tenderness posteriorly is a classic PE finding in

Answer 31

Endometriosis

Question 32

Medical treatment for endometriosis that induces atrophic changes to implants

Answer 32

Danazol

Question 33

Drug class used in medical oophorectomy for endometriosis

Answer 33

GnRH Agonist (Leuprolide, Goserelin)

Question 34

definitive treatment for Endometriosis

Answer 34

Hysterectomy