Cervix Flashcards
When to start pap smear in relation to onset of sexual activity
Within 3 years of onset of sexual activity
Age when papsmear should be done if without sexual activity
21
Conventional pap smear is performed annually until
30 yo
Pap smear is done every __ after age 30 if negative of CIN for 3 consecutive years
2-3 years
Age when to discontinue pap smear if with negative cytology results for 3 consecutive years,
No abnormal test results in the past 10 years and
No new sexual partner
65-70
Post total hysterectomy pap smear can be discontinued except
HSIL History
Immunocompromised
DES Exposure
Unsatisfactory Sample of Pap smear
Lack of Label
Loss of Transport Medium
Scant Cellularity
Contamination
Label the Medium if with Scant Contamination
HPV DNA, CIN 1, dysplasia
LSIL
CIN 2, CIN 3
HSIL
Inc Nuclear to cytoplasmic ratio Hyperchromasia Perinuclear Halo Irregular Nucleus Clumping chromatin
Cervical dysplasia: Atypical
Colposcopy Done
ASC-US ASC-H LSIL (CN 1) HSIL (CN 2,3) Glandular Lesion
Repeat cytology in 12 mos
Recommended when results of biopsy show CIN 1 after being previously (ASCUS, LSIL, HPV 16 or 18)
Observation with ________ can be an option for those with CIN 1: ASC-H, HSIL provided Colpo is negative
Colposcopy and cytology at 6 months interval for 12 months
Observation thru ___ every ___ can be an option for those with CIN 2,3 biopsy results with adequate colposcopy.
Colposcopy and cytology at 6 months interval for 12 months
Options for those with CIN 2,3 biopsy results with inadequate colposcopy
Excision
Ablation of transformation zone
2nd most common CA among women
Cervical CA
Necessary cause of Cervical CA
HPV
Most common histology of cervical cancer
Histologic type of cervical cancer arising from the ectocervix
Squamous cell CA
Histologic type of cervical cancer arising from the endocervix
Adenocarcinoma
Most common symptom of cervical cancer
Vaginal Bleeding - brown, foul smelling discharge
Level of prevention of cervical cancer: pap smear
Secondary
Pattern of spread of Cervical CA
Lymphatic
Level of prevention of cervical cancer: abstinence
Primary
Level of prevention of cervical cancer: Vaccination vs HPV 16,18
Primary
Primary level of cervical cancer prevention
Abstinence
Lifetime mutual monogamy
Barrier protection
Vaccination vs HPV 16,18
Secondary level of cervical CA prevention
any SCREENING test
Stage of cervical cancer: confined to cervix
1
Stage of cervical cancer: beyond uterus, not extending to pelvic wall or lower 1/3 of vagina
2
2A (-) Parametrial invasion
2B (+) Parametrial Invasion
Stage of cervical cancer: lower 1/3 of vagina with or without hydronephrosis or non-functioning kidney
3
3A (-) Pelvic wall invasion
3B (+) Pelvic wall invasion
Stage of cervical cancer: bladder or rectal invasion
Stage of cervical cancer: beyond true pelvis
4
4A - Adjacent Organs
4B - Distant Organs
Preferred First Line Single Agent in Chemotherapy of Cervical CA
Cisplatin
