USMLE 3/19/14 Flashcards
What type of mutation is associated with most severe NF2 disease?
Nonsense
Complication of untreated pseudo tumor cerebri?
Blindness
Neurologic signs of pseudo tumor cerebri?
Papilledema, visual field defects, CN VI palsy
Treatment for pseudo tumor cerebri?
Weight reduction, acetazolamide
Symptoms of idiopathic intracranial hypertension
headache, transient vision loss, pulsatile tinnitus, diplopia
CSF: IIP?
Opening pressure >250 with normal analysis
Cerebellar hemorrhage: presentation
ataxia, vomiting, occipital headaches, gaze palsy, facial weakness; NO HEMIPARESIS
CNS lymphoma: features
CSF EBV DNA, weakly ring-enhancing mass that is usually solitary and periventricular
Findings: basal ganglia hemorrhage
hemiplegia, hemi-sensory loss; homonymous hemianopsia, gaze palsy; stupor and coma
Findings: cerebellar hemorrhage
neck stiffness, facial weakness, NO hemiparesis, stupor or coma from brainstem herniation
Findings: thalamic hemorrhage
hemiparesis, hemi-sensory loss; upgaze palsy, nonreactive miotic pupils; eyes deviate TOWARD hemiparesis
Findings: cerebral lobar hemorrhage
seizures, contralateral homonymous hemianopia (occipital lobe), contralateral paresis/plegia (frontal lobe); contralateral hemiparesis (parietal lobe); eyes deviate AWAY from hemiparesis
Findings: pontine hemorrhage
deep coma and total paralysis within minutes; PINPOINT reactive pupils
Posterior limb of internal capsule: infarct
unilateral motor impairment; no sensory/cortical deficits; no visual field abnormalities
MCA occlusion
contralateral sensory & motor weakness (face, arm & leg); conjugate eye deviation TOWARD infarct; homonymous hemianopia; aphasia (dominant hemisphere); hemineglect (nondominant hemisphere)
