Usage of antibiotics in poultry and swine Flashcards
usage of antibiotics in swine
overuse is more common in swine and poultry
resistance is very frequent in these species
narrow spectrum penicillins spectrum
effective against gram positive bacteria
injectable penicillins for pigs
- Benzylpenicillin – procaine
- Benzylpenicillin – benzathine
(+ Dihydrostreptomycin)
the combinations of penicillins - duration of action, synergistic drug and administration
These combinations give a relatively quick and long duration of action. Can last for up to 3 days, depends on the inhibitory concentration of the bacteria.
Both combinations release penicillin and this penicillin has good synergism with dihydrostreptomycin. These products usually contain dihydrostreptomycin because of the synergism. They are given IM
which drug is given orally and what does it take
phenoxymethyl-penicillin
resistant to gastric acid. clostridium perfringens and fastidious gram-negative bacteria
actinobacillus pleuropneumonia
trueperella multocida
indications of narrow spectrum penicillins
swine eryspelas
streptococcus suis
trueperella pyogens
leptospira spp (abortion)
what AB to use agaisnt glassers diaseas and what bacteria?
sensitive to narrow spectrum penicillin, broad is more effectie
haemophilus parasuis s.suis(fastidious gram-negative)
broad spectrum penicillins substance
amoxicillin
and amoxicillin/clavulanic acid
indications of amoxicillins (su)
swine erysipelas C.perfringens C S.suis glassers disease APP, PM PDS (MMA) enteritis: E.coli salmonella spp
route of administration of amoxicillin
IM
PO
amoxicillin/clavulinic acid indication
PDS (MMA)
APP, PM - enteritis: E.coli, salmonella spp
swine erysipelas suis
what is the advantage of amoxicillins
it can be given orally (best with water)
bacteria frequently resistant to amoxicillin
salmonella and E.coli
in what situation is amoxicillin especially good
E.coli UTI
3rd generation cephalosporin used in swine
ceftiofur
indications and route of administration for ceftiofur
respiratory tract: APP, PM
s.suis, glassers disease
enteritis: E.coli, salmonella spp
PDS
IM
4th generation cephalosporin
cefquinome
indications and route of administration of cefquinome
respiratory tract: APP, PM
s.suis, glassers disease
enteritis: E.coli, salmonella spp
PDS
IM
the two forms of the ceftiofur
hydrochloric acid - active for 1 day
crysalline free acid form - 1,5-2 weeks
different substances of aminoglycosides used for swine
gentamicin
apramycin
spectinomycin
indications/spectrum of the aminoglycosides
gentamicin and apramycin: E.coli, salmonella spp
spectinomycin: mycoplasma spp
aminoglycosides administration
gentamicin + spectinomycin: IM, PO
apramycin: PO