Urology / Renal (5%) Flashcards
Causes of orthostatic hypotension
Medications Hypovolemia Anemia Heart dz Diabetes Parkinson's Disease
Treatment for orthostatic hypotension
- Tx underlying etiology
- Have pts rise slowly from sitting to standing
- Increase fluid and sodium intake
Treatment for orthostatic hypotension if conservative measures fail
Fludrocortisone - first line therapy
Most common solid tumor in men 15-40 y/o
Testicular Carcinoma
Risk factors for testicular carcinoma
Cryptorchidism - 40 fold risk
Caucasians
Klinefelter’s syndrome
Most common type of testicular carcinoma
Germinal Cell Tumors
Seminomas are more common in ____________, while nonseminomatous carcinomas of the testicles are more common in _________
Men (30-40)
Boys < 10 y/o
Signs/symptoms of testicular carcinoma
- Painless testicular nodule, solid mass or enlargement
- Hydrocele present in 10%
- Gynecomastia
Diagnosis of testicular carcinoma
- Scrotal ultrasound
2. Alpha-fetoprotein, BhCG, LDH
Management of low-grade nonseminoma testicular carcinoma
Orchiectomy with retroperitoneal lymph node dissection
Management of low-grade seminoma testicular carcinoma
Orchiectomy, radiation
Management of high-grade seminoma testicular carcinoma
Debulking chemotherapy
Followed by orchiectomy and radiation
Most common abdominal malignancy in children - usually presents within 5 y/o
Wilms Tumor
Signs/Symptoms of Wilms Tumor
Painless, palpable, abdominal mass - MC
Hematuria
HTN
Anemia
Diagnosis of Wilms Tumor
- Abdominal ultrasound - best initial
2. CT w/ contrast or MRI
Management of Wilms Tumor
Nephrectomy followed by chemotherapy
Lung is common site for METS
Most common form of bladder carcinoma
Transitional cell
Risk factors for bladder carcinomas
- Smoking
2. Occupational exposure
Medications that are known to cause bladder cancer
- Cyclophosphamide
2. Pioglitazone
Signs/Symptoms of bladder cancer
Painless gross or microscopic hematuria
Irritative sx
Diagnosis of bladder cancer
Cystoscopy with biopsy
Management of bladder cancer that is localized/superficial
Transurethral resection bladder tumor (TURBT)
Intravesical chemo
Management of bladder cancer that is invasive (advanced or involving muscular layer)
Radical cystectomy
Chemo
XRT
Management of recurrent bladder CA
BCG (bacillus calmette-guerin) vaccine intravesicular
95% of tumors originating in the kidney are _______________
Renal cell carcinomas
Renal cell carcinomas are tumors of the ___________ ___________ __________
Proximal convoluted tubule
Most metabolically active
Risk factors for renal cell carcinoma
Smoking
Dialysis
HTN
Obesity
Classic triad of renal cell carcinoma
- Hematuria
- Flank/abdominal pain
- Palpable mass
- Left sided varicocele - blocks testicular vein drainage
Diagnosis of renal cell carcinoma
- CT scan - first test to be done
- Ultrasound
- MRI
Management of renal cell carcinoma for stages I-III
Radical nephrectomy
Usually resistant to chemo and radiation
Management of renal cell carcinoma that has bilateral involvement or pt has solitary kidney
Partial nephrectomy
Renal artery stenosis causes reduction of blood flow to the kidney, leads to ______
CKD