Neurology (5%) Flashcards
Risk factors for carotid disease
HTN
DM
Smoking
Hypercholeseterolemia
A pt with carotid disease may have a history of:
Stroke
TIA
Focal motor deficits, weakness, clumsiness, expressive or cognitive aphasia
May be reversible neurological deficits or fixed
Treatment for carotid artery dissection
Anticoagulation for 3-6 mo
Signs/Symptoms of carotid disease
Amaurosis Fugax (transient monocular blindness) Hollenhorst Plaques (found in retinal exam - evidence of previous emboli) Carotid bruit
Amaurosis Fugax
Seen in carotid disease
Transient monocular blindness
Usually described as a shade being pulled down in front of pt’s eye
Due to occlusion of a branch of the ophthalmic artery
Diagnosis for carotid disease
- Carotid duplex screening
2. MRA (magnetic resonance angiogram) - best for degree of stenosis
Management of carotid disease
- Antiplatelet therapy with aspirin to prevent neurologic events
- Endarterectomy (if indicated)
Indications for endarterectomy
- > 75% stenosis
- > 70% stenosis and symptomatic
- Bilateral dz and symptomatic
- > 50% stenosis with recurrent TIAs despite aspirin therapy
Major complications of endarterectomy
MI (major cause of death post-procedure)
Stroke
Mechanism behind subarachnoid hemorrhage
Berry aneurysm rupture
Signs/Symptoms of subarachnoid hemorrhage
Thunderclap H/A (worst of my life) \+/- unilateral, occipital area \+/- LOC, N/V May have meningeal sx: stiff neck, photophobia, delirium Usually no focal neurological deficits
Diagnosis of subarachnoid hemorrhage
- CT first
- If CT negative, perform LP (looking for blood, increased pressure)
- 4-vessel angiography after confirmed SAH
Management of subarachnoid hemorrhage
- Supportive: bed rest, stool softeners, lower ICP
- Surgical coiling or clipping
- +/- BP lowering (Nicardipine, Nimodipine, Labetalol)
Mechanism behind subdural hematoma
Tearing of cortical bridging veins
Seen most commonly in the elderly
Most common cause of subdural hematoma
Blunt trauma - often causes contrecoup bleeding