Urology and Renal Flashcards
Define balanitis.
Inflammation of the foreskin and head of the penis.
What S/S are most commonly associated with balanitis?
Patient will be uncircumcised male c/o itching and burning of penis presenting with erythema, inflammation, and scant white discharge.
What is the most common pathogen that causes balanitis?
Candida
What is the typical treatment for balanitis?
Improved hygiene, topical antifungal or abx.
What patients are more susceptible to balanitis and how are they treated?
Diabetics –> hygiene, glucose control, clotrimazole
Describe the pathophysilogical process leading to benign prostatic hyperplasia (BPH).
proliferation of fibrostromal prostate tissue –> urethral compression –> obstruction of urinary outlet
What clinical features will be indicative of BPH?
Slightly elevated PSA, enlarged prostate on DRE, hesitancy and straining, post-void dribbling, nocturia, urgency, frequent UTIs.
What are treatment options for BPH?
Behavioral: imit fluids before bed
Pharm: alpha antagonists (prazosin), PDE-5 inhibitors (tadalafil), Anti-Ach agents
Procedures: balloon dilation, microwave irradiation, stent placement, transurethral resection/incision
What is the most common cause of non-gonococcal urethritis?
Chlamydia
Differentiate urethritis caused by chlamydia from that of gonorrhea.
IN chlamydia, discharge is usually watery and less painful than in gonorrhea.
What is the typical presentation of chlamydia in females and what is the risk of disease progression?
Usually asymptomatic –> progress to PID, cervicitis, salpingitis
What is the most common cause of female infertility?
Chlamydia
How is the diagnosis of chlamydia made?
Typically presumptive based on symptoms –> bacteria is gram negative on testing
What is the treatment for chlamydia?
Doxycycline, azithromycin, erythromycin –> preferred in pregnancy
Define cystitis and state the most common cause and progression of the disease.
Bladder infection. Usually E. Coli that ascends from urethra –> often appears in women after sexual intercourse.
What clinical features are consistent with a diagnosis of cystitis?
H&P: Frequency, urgency, dysuria, maybe suprapubic tenderness.
UA: Pyuria, bacteriuria, may have hematuria –> urine culture will be positive for offending organism
What imaging is used to diagnose cystitis?
None needed unless suspected pyelonephritis, recurrent infections, or abnormal anatomy.
What is used in the treatment of cystitis?
Sx relief: hot sitz baths, phenazopyriadine (aka “azo”)
Abx: Bactrim, nitrofurantoin, fluoroquinolones if severe or recurrent.
What type of drug is phenazopyriadine and what is its primary AE?
Urinary analgesic –> turns urine orange
Describe the pathogenesis and causative agents in epididymitis.
Retrograde spread of organism through the vas deferens. YOunger than 35, organism is usually G/C –> older than 35 is E. Coli.
Describe S/S consistent with epididymitis.
Dull ache in scrotum that can radiate up ipsilateral flank, swollen epididymis, fever, chills.
Describe Prehn’s sign and its finding in epididymitis.
Positive when scrotal pain is relieved with elevation of the scrotum –> positive sign indicates epididymitis.
What urinalysis findigns are consistent with epididymitis?
Pyuria, bacteriuria –> urine culture will be positive for offending organism
What is the treatment for epididymitis?
< 35 yoa: ceftriaxone + doxycycline
> 35 yoa: ciprofloxacin
Define and describe glomerulonephritis.
Deposition of inflammatory proteins in glomerular membranes as result of immunologic response
What is the prognosis in glomerulonephritis?
Excellent in kids, worse in adults - especially with pre-existing renal disease.