Urology Flashcards

1
Q

Geniturinary tract pain could be due to

A
  1. Obstruction: stone/retention
  2. Inflammation
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2
Q

Parenchymatous organ inflammation (pyelonephritis, epididmitis) produces_____ Pain, while inflammation of the mucosa of a hollow viscous, such as bladder produces________

A

Severe, discomfort

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3
Q

Site of renal pain is

A

At the costovertebral angle just lateral to sacro-spinalis muscle, beneath 12th rib

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4
Q

Where does renal pain radiate to?

A

Flank anteriorly towards upper abdomen and umbilicus, and might be to the testis/labium

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5
Q

Describe the character of renal pain?

A

Inflammatory: steady dull aching
Obstruction: fluctuating colicky

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6
Q

Justify: obstructive renal pain is associated with GI symptoms

A

Due to reflex stimulation of the celiac ganglion

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7
Q

Lower urinary tract symptoms divides into:

A
  1. Voiding (obstructice) symptoms
  2. Storage (irritative) symptoms
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8
Q

Mention bladder irritative symptoms

A

Frequency
Urgency
Nocturia

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9
Q

Mention LUT obstructive symptoms

A

Hesitancy
Intermittency
Abdominal straining
Weak stream(bifid)
Post voiding dribbling
Sense of incomplete evacuation

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10
Q

Define hematuria

A

Presence of blood in urine > 3 RBC’s per high power microscopic field

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11
Q

Initial hematuria indicates

A

Indicates problem of urethra or prostate

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12
Q

Terminal hematuria

A

Bladder or prostate

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13
Q

Total hematuria

A

Kidney, ureter or bladder

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14
Q

Define infertility

A

Couple failing to conceive after 1 yr of regular unprotected intercourse

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15
Q

Normal Urine pH

A

5.5-6.5

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16
Q

Highly acidic urine is found in

A

Hyperuricosuria

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17
Q

Normal WBCs in urine microscopy

A

Male: up to 2/ HPF
Females: up to 5/HPF

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18
Q

Chemical dipsticks screen for:

A

Glucose, pH, protein, hemoglobin, ketones

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19
Q

Normal serum creatinine

A

Adults: 0.8-1.2mg/dl
Infants: 0.1-0.4 mg/dl

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20
Q

Why is BUN much less accurate than creatinine in indicating GFR

A

As its influenced by many factors such as: dietary protein and hydration

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21
Q

Normal BUN/Creatinine ratio

A

10/1 to 20/1

High: dehydration, renal ds, bleeding
Low: pregnancy, low prtn diet and hepatic ds

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22
Q

PSA

A

Prostatic specific antigen < 4 ng/ml

4-10 grey zone
>10 malignancy?

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23
Q

If PSA > 10, perform:

A

TRUS guided biopsy check for malignancy

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24
Q

If PSA is in grey area what do we do next?

A

Grey zone 4-10 ng/ml

Get a PSA Free/ total ratio

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25
Q

TRUS

A

Transrectal ultrasound scan: prostate viewing

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26
Q

Most used screening imaging study in urology

A

Ultrasound

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27
Q

Disadvantage of U/S

A

No functional data
Poor anatomical imaging of ureter

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28
Q

To detect mass and torsion in testis use

A

Scrotal Doppler U/S

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29
Q

Advantages of IVU

A

Anatomical and functional data of urinary tract

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30
Q

Disadvantage of IVU

A

Contract allergy and adverse effects
Radiation exposure

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31
Q

Phases of IVU imaging

A

Immediate film
Nephrogram phase (5-15min)
Ureterogram phase (30min)
Cystogram phase (45 min)
Post voiding film

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32
Q

Cobra head appearance on IVU

A

Ureterocele

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33
Q

Key hole sign

A

Posterior uretheral valve anomaly

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34
Q

Uses of CT in urology

A
  1. Radiolucent/radio-opaque stone detection
  2. Tumor detection & staging
  3. Urinary tract trauma
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35
Q

Varicocele commonest side

A

Left side

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36
Q

Uses of MRI in urology

A

Replacing CT when contraindicated
Renal/ adrenal tumors
Vascular invasion

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37
Q

Renal isotope scan uses

A
  1. Need for surgery: onstructive or nonobstructive hydronephrosis
  2. Evaluate split renal function
  3. Monitor effect of therapy
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38
Q

MAG3 isotope

A

Evaluate Renal function and plasma flow as it is cleared by tubular secretion & no glomerular filtration

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39
Q

DPTA

A

Evaluate obstruction and renal function as it is cleared by glomerular filtration

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40
Q

DMSA isotope

A

Cleared by filtration and secretion
Used to evaluate renal scarring (renal cortical image)

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41
Q

Most common type of kidney injury?

A

Blunt retroperitoneal

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42
Q

Meteorism

A

Abdominal distention, nausea and vomiting within 24-48 hr due to retroperitoneal hematoma involving splanchnic nerves

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43
Q

Kidney injury grading

A

Grade 1: subcapsular hematoma only
Grade 2: perirenal hematoma and <1cm cortical laceration; without urinary extravasation
Grade 3: grade 2+ > 1cm cortical laceration
Grade 4: laceration thru corticomedullary junction with urinary extravasation + segmental vessel injury contained hematoma
Grade 5: shattered kidney, pedicle injury, avulsion

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44
Q

Early complications of kidney injury

A

1- anuria
2- clot retention
3. Paralytic ileus
4- perinephric abscess
5- urinary fistula
6. Pseudohematohydronephrosis
7. Intraperitoneal hem + peritonitis

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45
Q

Late complications of kidney injury

A
  1. Hydronephrosis: periureteral fibrosis
  2. Nephroptosis: tear of supporting tissue
  3. Hypertension: fibrosis of kidney
  4. Aneurysm of renal artery
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46
Q

Gold standard investigation for kidney injury

A

CT contrast

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47
Q

Initial evaluation test for kidney injury

A

Ultrasound

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48
Q

Lack of parenchymal contrast enhancement using CT contrast suggests

A

Arterial injury

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49
Q

Why is ultrasound not a gold standard test in renal injury?

A

It only identifies retroperitoneal hematoma, but does not clearly delneate lacerations or vascular or collecting injuries

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50
Q

When is intravenous pyelography indicated in renal injury

A

“Single shot’’ intra-operative IVP in haemodynamically unstable patients is better instead of CT (no time)

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51
Q

Indications of nephrectomy

A

In extensive renal injuries or unstable, patient in a normal contralateral kidney

In an unstable patient with low body temperature and coagulopathy in a normal contralateral kidney

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52
Q

The treatment of choice for the majority of renal injuries is

A

Non-operative management

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53
Q

Indications for surgical management of kidney injury

A
  1. Haemodynamically instability
  2. Exploration for associated injuries
  3. Grade 4 and 5 injury
  4. Expanding or pulsatile peirenal haematoma
  5. Pre-existing renal pathology requiring surgery
  6. Vascular injuries after failed and angiographic treatment.
54
Q

The two most common signs and symptoms of major bladder injuries are

A

Gross haematuria and abdominal tenderness

55
Q

The standards of care in urethral injury is

A

Suprapubic cystostomy

56
Q

Eggplant deformity

A

Trauma of penis: Swelling and ecchymosis of the penis due to rupture of Tunica Albina the cover the corporal cover no

57
Q

Tear in tunica albugenia is investigated by

A

Penile duplex

58
Q

Flame shaped collection of contrast in the pelvis

A

Extra-peritoneal injury

59
Q

Most extraperitonial bladder rupture heal within____ days

A

10 days

60
Q

Blunt extra peritoneal bladder rupture is managed by?

A

Foley catheter drainage

61
Q

What is the most common cause of urethral stricture?

A

Endoscopic / catheter trauma

62
Q

What are the management steps upon suspected testicular torsion?

A
  1. scrotal duplex to confirm diagnosis
  2. Immediate surgical exploration and don’t wait for laboratory studies.
63
Q

Clot retention is confirmed by?

A

Cystoscopy

64
Q

During distal radio-cephalic AV fistula care must be taken not to injure

A

Dorsal branch of radial nerve.

65
Q

Care must be taken not to injure_____ during brachio-cephalic or brachio-basilic fistula

A

Median nerve at cubital fossa

66
Q

Autogenous access needs _______weeks for proper vein maturation

A

6-8 weeks

67
Q

Advantages of autogenous AV access over prosthetic AV graft?

A
  1. Resist infection
  2. Longer estimated usage time
68
Q

Prothetic arteriovenous graft needs_______weeks to start using it

A

1-2 weeks

69
Q

Define a cyst

A

A sac containing fluid lined by epithelium or endothelium

70
Q

In dermoid or branchial cyst the contents are like ____

A

Tooth paste

71
Q

The wall of a false cyst is lined by

A

Fibrous or granulation tissue

72
Q

Examples of a pseudo cyst

A
  1. Pseudo cyst of the pancreas(encysted collection of fluid in the lesser sac)
  2. Tumor Cystic degeneration
73
Q

Complications of cysts

A
  1. Infection
  2. Hemorrhage
  3. Torsion
  4. Calcification
74
Q

Cock’s peculiar tumor

A

Infection complicating sebaceous cyst on the scalp by forming an ulcer

75
Q

Type or shape of the incision to treat sebaceous cyst

A

Elliptical incision to avoid recurrence

76
Q

Complications of sebaceous cyst

A

Infection
cock’s peculiar tumor: ulceration
sebaceous horn

77
Q

Mention 4 types of dermoid cyst

A

Sequestration dermoid
Tubulodermoid
Teratomatous dermoid
Implantation dermoid

78
Q

Common side of sebaceous cyst

A

Face, scalp and scrotum, but never palms and soles

79
Q

XRay or CT must be performed before excision of a head dermoid cyst. Why

A

Exclude communication with intracranial dermoid

80
Q

Describe a sequestration dermoid cyst

A

Cystic, smooth, rounded, not attached to skin, but maybe adherent to underling structures, there may be indentation of underlying bone. It is lined by epidermis and contain a paste like desquamated material.

81
Q

Mucus cyst more common in

A

Female
Middle age
Dorsal DIP Joint

82
Q

Immobile and ill-defined swelling at friction points (bone&skin)

A

Bursitis

83
Q

Hallmark symptom of bursitis is

A

Localized swelling at the joint

84
Q

Semimembranous bursitis is located on

A

Medial side of popliteal fossa

85
Q

Semimembranousus TTT

A

Primary type: excision
Secondary type: treat cause

86
Q

Midline popliteal fossa’s swelling

A

Baker’s cyst

87
Q

Baker’s cyst happens mostly secondary to:

A

Osteoarthritis

88
Q

Hallus valgus

A

Bunion

89
Q

Example for an adventitious bursae

A

Bunion

90
Q

Preferred type of biopsy in soft tissue tumours

A

True cut needle biopsy

91
Q

Common site for diffuse lipoma is

A

Neck

92
Q

Lipoma can occur anywhere in the body except

A

The cranium

93
Q

The line of cleavage in lipoma facilitates

A

Enucleation of the tumour

94
Q

The line of cleavage encapsulated lipoma occurs between

A

True capsule (fibrous capsule )
false capsule (surrounding tissue)

95
Q

Lipoma is classified according to

A

Capsule
Structure:
Site

96
Q

What is the commonest type of lipoma? And it’s favourable site.

A

Subcutaneous lipoma; back, shoulder buttocks, forehead and limbs

97
Q

Pathognomonic signs of subcutaneous lipoma

A

A well defined slippery edge and Dimpling of skin on displacement of the swelling (lobulation)

98
Q

Dercum’s disease (adiposis dolorosa)

A

Tender deposit of fat, specially on the trunk and is an associated condition with multiple lipomatosis

99
Q

Subsynovial lipoma can be mistaken for?

A

Baker’s cyst

100
Q

Retroperitoneal lipoma may grow into ______size

A

Enormous

101
Q

Most dangerous lipoma is:

A

Sub-mucous lipoma:
Larynx: respiratory obstruction
Intestine: intussusception

102
Q

Treatment of lipoma

A

Surgical excision indicated if a lipoma is causing trouble on account of its site, size, appearance, or the presence of pain

103
Q

Neurofibroma origin

A

Connective tissue of nerve sheet . In relation to cranial 5&8 or a peripheral nerve

104
Q

Describe neurofibroma

A

Arise from any nerve usually in subcutaneous tissue, firm, tender, well defined slowly growing swelling that can be moved across, but not along the nerve from which it arises.

105
Q

Von Recklinghausen’s disease

A

Generalized neurofibromatosis (AD)

106
Q

Types of neurofibroma

A
  1. Solitary neurofibroma
  2. Generalized neurofibromatosis
  3. Acoustic neuroma
  4. Plexiform neurofibomatosis
  5. Elephentiasis neurofibromatosa
107
Q

Gamma knife radio-surgery

A

Acoustic neuroma

108
Q

Pachydermatocele

A

Plexiform neurofibromatosis

109
Q

Types of neuroma

A

Tumors in sympathetic system
1. Gangiloneuroma
2. Neuroblastoma
3. Myelinic neuroma

110
Q

Neuroblastoma resembles_______ and disseminate by________ and is treated by_______

A

Round cell sarcoma, blood , surgery +/- chemo

111
Q

Common sites of Gangileoneuroma

A

Connection with sympathetic plexus so:

In the neck, thorax or retroperitoneal tissue

112
Q

Myelinic neuroma consists of_______only and arises in connection with ________ or ______

A

Nerve fibers, spinal cord or pia matter

113
Q

A lobulated encapsulated, soft, whitish swelling that displace the nerve from which it rises

A

Schwanoma (neurilemmoma)

114
Q

Varieties of fibroma

A
  1. Soft subcutaneous nodule (fibroma mole)
  2. Pedunculate lesion of oral mucosa ( fibroma durum)
  3. Pleomorphic fibroma
115
Q

Aggressive fibromatosis

A

Desmoid tumor

116
Q

Example of intermediate tumor (locally invasive)

A

Desmoid tumor

117
Q

Histology of desmoid tumor

A

Uncapsulated, composed of fibrous tissue containing multinucleated giant cells

118
Q

Soft tissue tumours that can be treated by chemo

A

Desmoid tumor and neuroblastoma

119
Q

Commonest site of desmoid tumor

A

Anterior abd wall and shoulder girdle

120
Q

Urine will pass to _______ in an interior bulbar urethra injury (fall astride)

A

Connective tissue of scrotum

121
Q

Pelvic fracture with highly displaced prostate (non palpable on PR) and a perineal oedema is suggestive of

A

Membranous urethral rupture

122
Q

What is the normal intra-vesical pressure at the beginning of micturition?

A

30 cm of water

123
Q

Mention some features seen in bladder compensation to BPH

A

Detrusor muscle hypertrophy
Trabiculation
Cellules
Diverticula

124
Q

Describe trabiculations of the bladder

A

muscle bundle with deposit of interstitial collagen fibers, becomes taut, and give an interwoven appearance to the mucosa)

125
Q

Score used to ttt BPH

A

IPSS International prostate symptom score

0-7 mild
8-19 moderate
20-35 severe

126
Q

If BPH is associated with hematuria then _________ is mandatory to rule out other bladder pathology

A

Cystoscopy

127
Q

DD and what to exclude when making a diagnosis of BPH

A

Urethral stricture (cystoscopy)
Bladder neck contracture (cystoscopy)
Trauma (history)
Bladder stone (pain and hematuria)
UTI (urinalysis and culture)
Cancer prostate (DRE and high PSA)
Neurogenic bladder DM

128
Q

Adverse effects of alpha blockers

A

Asthenia
First dose phenomenon
Dizziness
Postural hypotension
Retrograde ejaculation

129
Q

Finastride is a competitive injibitor of type ___ 5alpha reductase enzyme while dutasteride is a competitive inhibitor for type ______
Maximum volume suppression of BPH achieved after ______

A

2 (prostate only)
1&2 (1 in prostate, liver and skin)
6 months

130
Q

Relative surgery indication in BPH

A
  1. Hematuria
  2. Recurrent lower UTI
  3. Bladder stone
  4. Moderate symptoms (moderate IPSS)
  5. Bad compliance
131
Q

Absolute indication of surgery in BPH

A
  1. Severe symptoms (severe IPSS)
  2. Recurrent acute retention
  3. Upper urinary tract affection
  4. Uraemia
  5. Failure of medical treatment