Cardiology Flashcards
Drugs in Hypertensive crisis
1.Glyceryl trinitrate: 0.6 - 1.2 mg/hr infusion
2.Sodium nitroprusside: 0.3-10 ug/kg/min infusion
3.Hydralazine: 1.5-5 ug/kg/min infusion
4.Labetolol: 20mg/m max 200-300mg infusion
Goal of hypertensive crisis
Reduce BP within 24-36 hrs to 150/90
Goal for hypertensive emergency and define
BP >200/120 with TOD
Reduce BP by 20-25% within 1-2hrs using IV agents
Goal of hypertensive urgency and define
Reduce BP within 24-48hrs usually using oral drugs
BP >200/120 with no TOD
Heart failure treatment
- Bed rest: renal perfusion and diuresis
- Salt and fluid restriction
- Diuretics
- ACE-I (vasodilators)
- BB (start low and go slow)
- Digitalis
- Potent inotropic (dopamine, dobutamine, PDE-I amrinone)
- CRT
- Treat precipitating factors
- Treat complications (arrhythmias/ thrombosis)
Digitalis indication
Chronic heart failure on left systolic dysfuntion
Showing signs and symptoms while receiving standard therapy or AF pts
PCWP at 20 and 25mmHg?
@20= Interstitial edema (kerly B lines on CXR)
@25= alveolar edema (bat’s wing on CXR)
Causes of AHF
- Acute LVF - infraction/ myocarditis
- MS and aggravating factors as AF
- Acute MR
Frothy pink sputum
Pulmonary edema
Causes of high COP failure
- Wet beriberi
- Chronic severe anemia
- Thyroxtoxicosis
- Pregnancy
- AV fistula
- AR and MR
- Paget’s ds of bone
Note: increased tissue demand with semi diseased heart
Managment of acute LHF
- Bed rest, oxygenation and hospitalization
- Frusemide 40-80mg IV max 200mg
- Morphone 2-5mg/IV with metaclopramide 10mg/IV
- Venous venodilators: nitroglycerin 5-10ug/m
- Na Nitropruside max 20-30ug/min if HTN not less than 100mmhg Bp
- Dobutamine or dopamine
- IV digitalis if AF
- Aminophylline 5mg/kg IV infusion over 10min
- Tracheobronchial aspiration
- Ultrafiltration, rotating tourniquets, intra aortic balloon
- Treat precipitating factors
NYHA classification system of the heart failure symptoms
Class 1: no limitation of ordinary physical activity
Class 2: slight limitation with ordinary physical activity
Class 3: marked limitation less than ordinary activity lead to marked symptoms
Class 4: symptoms present at rest; cant carry out any physical activity without discomfort
Angina equivalent
Myocardial ischemia not presenting with anginal pain but with dyspnea, fatigue, faintness
Angina never to be
- Localized
- Stitching or throbbing
- <30sec or >30min (except unstable angina)
Anginal pain precipitated by
- Cold
- Exertion
- Heavy meal
- Vivid dreams (nocturnal angina)
Angina signs
S4
MR murmur
Xanthelasma or signs of anemia
Digoxin tox ECG
Sagging ST segment
Bigeminy
Ventricular tachy
Heart block
Extrasystoles
First symptom of digitalis tox
Anorexia
Treatment of digitalis tox
Stop drug
Give K
Digitalis Ab
Stop diuretics
Treat arrhythmias
Hemoperfusion
Coronary angiography
Diagnostic and theraputic
Stenosis > 70% significant
Cardiac scan
Assess coronary perfusion using thalium or technitium IV
Echocardiography in angina investigation
For ventirular function EF and wall motion abnormalities
Which vessels used in CABG
- Saphenous v.: right coronary and LCX
- Left Internal mammary artery : left main and LAD
- Right internal mammary artery: right CA
BB contraindicated in?
Prinzmetal angina
Bronchial asthma
DM
Peripheral artery ds