Urological Diseases Flashcards
Suggest 6 potential causes of haematuria
- Bladder cancer (particularly if painless)
- Renal cancer
- UTI
- Stones
- Prostate disease
- Nephrological disease
On investigation, how would you distinguish glomerular bleeding from other causes of haematuria?
Presence of dysmorphic RBC’s seen on urine sample microscopy
Give 5 metabolic conditions which can give rise to recurrent kidney stones
- Type 1 renal tubular acidosis
- Hyperparathyroidism
- Cystinuria
- Sarcoidosis
- Crohn’s disease (enteric hyperoxaluria)
What are the 3 most common renal stone compositions?
- Calcium oxalate (75%)
- Struvite ‘staghorn’ (10%)
- Urate (radiolucent) (10%)
Name 2 common benign renal tumours
- Angiomyolipomas
2. Oncocytoma
What are the 2 most common malignant tumours of the renal tracts?
- Renal cell carcinoma
2. Transitional cell carcinoma
Recall the classical triad of symptoms associated with renal cell carcinoma
- Haematuria
- Pain
- Flank mass
Give 5 risk factors associated with transitional cell carcinoma
- Smoking
- Cyclophosphamide
- Schistosomiasis
- Radiotherapy
- Occupational exposure
Recall 4 risk factors for papillary necrosis
- Analgesia e.g. NSAIDS
- Diabetes
- Sickel cell disease
- Infection
What is the most common genetic renal disease?
ADPKD - Autosomal dominant polycystic kidney disease
Outline 9 differentials for renal colic
- Pyelonephritis
- Ectopic pregnancy
- Torted ovarian cyst
- Appendicitis
- Diverticulitis
- Pancreatitis
- Cholecystitis
- Ruptured AAA
- MS pain
Give 2 antibiotics that can be administered IV for the treatment of pyelonephritis with pyrexia
- Gentamicin
2. Temocillin
Define stage pTa of bladder cancer
Tumour cells confined to the epithelium
Define cis stage of bladder cancer
Aggressive cells confined to the epithelium, usually a ‘flat tumour’
Define stage T1 of bladder cancer
Tumour cells in sub-epithelial connective tissue