Urinary System Flashcards

1
Q

Functions - Urinary system

regulation between water and electrolytes

A

Acid-base balance

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2
Q

Functions of urinary system

Secretion of ____ which is important for regulation of blood pressure

A

Renin

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3
Q

Functions of the urinary system

Secretion of ____ which stimulates erythrocyte production when blood oxygen is low

A

Erythropoietin

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4
Q

Functions of the urinary system

Conversion of Vitamin D to its active form ____ or ____

A

1,25- dihydroxyvitamin D3 or Calcitriol

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5
Q

Functions of the urinary system

_____ during starvation or periods of prolonged fasting

A

Gluconeogenesis

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6
Q

Each ___ consist of a thick cortex which surrounds the ____ → this is then divided into __ to __ renal pyramids

A

Kidney
Medulla

8 to 12

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7
Q

Kidney

Each pyramid comprises a

A

Renal lobe

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8
Q

Kidney

The apical papilla of each renal pyramid inserts into a ____ which is a subdivision of a ___

A

minor calyx
major calyx

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9
Q

Kidney

The __ carries urine from the renal pelvis and will exit the renal hilum → this where the renal artery and vein can be found.

A

Ureter

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10
Q

Functional Unit of the Kidney

A

Nephron

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11
Q

Its numbers reaches a million, consisting of a renal corpuscle and a long renal tubule, with a system of collecting ducts.

A

Nephron

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12
Q

Water and solutes in the blood leave the vascular space and enter the lumen of the nephron.

A

Filtration

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13
Q

Substances move from epithelial cells of the tubules into the lumen; after uptake from surrounding interstitium and capillaries.

A

Tubular Secretion

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14
Q

Substances move from the tubular lumen across the epithelium into the interstitium and surrounding capillaries.

A

Tubular Reabsorption

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15
Q

REMEMBER

The number of ___ decreases slightly in older adults which is accelerated by HYPERTENSION / High blood pressure.

A

Nephrons

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16
Q

At the start of each nephron is a ___ ___ about 200 um in diameter

A

Renal Corpuscle

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17
Q

This contains a tuft of glomerular capillaries surrounded by the Bowman’s Capsule

A

Renal Corpuscle

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18
Q

Renal corpuscle

The __ ____ enters and the ___ ___ leaves

A

Afferent arteriole
Efferent arteriole

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19
Q

Renal Corpuscle

It consists of a __ __ where the __ ___ __ begins.

A

Tubular pole
PROXIMAL CONVOLUTED TUBULE

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20
Q

Structure of the Bowman’s Capsule

surrounds the glomerular capillaries

A

Internal visceral layer

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21
Q

Structure of the Bowman’s Capsule

serves the capsule’s surface

A

Outer Parietal Layer

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22
Q

Structure of the Bowman’s Capsule

receives the filtered fluid and is located in between the capsular layers

A

Capsular Urinary Space

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23
Q

Structure of the Bowman’s Capsule

Inner Visceral Layer
- stellate cells

A

Podocytes

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24
Q

Structure of the Bowman’s Capsule

Inner Visceral Layer
- known as “secondary processes” and covers the capillary surfaces

25
Structure of the Bowman’s Capsule Inner Visceral Layer - Has direct contact with basal lamina
Pedicels
26
Structure of the Bowman’s Capsule Inner Visceral Layer (4)
Podocytes Pedicels Filtration slit pores Slit diaphragms
27
Structure of the Bowman’s Capsule 3 layer
Internal Visceral Layer Outer Parietal Layer Capsular urinary space
28
Renal tubules - histological features cells well stained with numerous mitochondria, prominent basal folds and lateral interdigitations; long microvilli, lumens often occluded
Proximal convoluted tubule
29
Proximal convoluted tubule locations
Cortex
30
Major functions - Renal tubules Reabsorption of all organic nutrients, all proteins, most water and electrolytes; secretion of organic anions and cations, H+, and NH4+
Proximal convoluted tubule
31
Loop of Henle few mitochondria
Thin limbs
32
Loop of Henle no microvilli, but many mitochondria
Thick ascending limbs
33
Loop of Henle Thin limbs locations
Medulla
34
Loop of Henle Thick ascending limbs locations
Medulla and medullary rays
35
Major functions - Renal tubules passive reabsorption of Na+ and Cl-
Thin limbs
36
Major functions - Renal tubules Active reabsorption of various electrolytes
Thick ascending limb
37
Histological features - Renal tubules cells smaller than in PCT short microvilli and basolateral folds, more empty lumens
Distal convoluted tubule
38
Distal convoluted tubule location
Cortex
39
Major Functions - Renal tubules Reabsorption of electrocytes
Distal convoluted tubule
40
Histological features - Renal tubules Collecting system - most abundant cuboidal to columnar, pale staining, distinct cell membranes
Principal cells
41
Histological features - Renal tubules Collecting system - few and scattered, slightly darker staining
Intercalated cells
42
Principal cells location
Medullary rays and medulla
43
Intercalated cells location
Medullary rays
44
Major Functions - Renal tubules Regulated reabsorption of water and electrolytes, regulated secretion of K+
Principal cells
45
Major Functions - Renal tubules Reabsorption of K+ (low K+ diet), help maintain acid base balance
Intercalated cell
46
Ureter and the Urinary Bladder ● Lining Epithelium
TRANSITIONAL EPITHELIUM
47
Ureter and the Urinary Bladder consisting of elliptical cells which are termed as “UMBRELLA CELLS”
Most superficial layer
48
Ureter and the Urinary Bladder consisting of several layers of low columnar to cuboidal cells
Intermediate layer
49
Ureter and the Urinary Bladder consisting of small basal cells (located nearest the basement membrane)
One layer
50
tube that carries the urine from the bladder to the exterior
Urethra
51
Urethra In men, the __ ducts for sperm transport during ejaculation join the urethra at the prostate gland.
2
52
Urethra Male - 3 segments
Prostatic urethra Membranous urethra Spongy urethra
53
Urethra - Male (Long and has 3 segments) → 3 to 4 cm long, extends through the prostate gland, lined by
Prostatic urethra Urothelium
54
Urethra - Male (Long and has 3 segments) → short segment, passes through an external sphincter, lined by
Membranous urethra Stratified columnar and Pseudostratified columnar epithelium
55
Urethra - Male (Long and has 3 segments) → 15 cm in length, enclosed within erectile tissue of the penis, lined by
Spongy urethra Stratified columnar and Pseudostratified columnar epithelium with Stratified squamous epithelium distally
56
Exclusively Urinary in function
Urethra Female
57
Urethra Female length is
3 to 5 cm
58
Urethra Female Initially lined with
TRANSITIONAL EPITHELIUM → then transitions to NON-KERATINIZED STRATIFIED SQUAMOUS EPITHELIUM