Urinary symptoms- classification. Flashcards

1
Q

points for classification or urological symptoms:

A

upper urinary tract symtpms

1-Pain

lower urinary tract sx:

2-Disturbances in urination

3-Changes in voided urine

4- Group of specific symptoms in Genito sexual symptoms

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2
Q

Describe the characeristics of pain in urology

A
  • pain refers to the diseased organ but not to the nature or type of disease e.g. loin pain might suggest renal diseases
  • Pain is as a result of enlargement of the organ,
    • sudden enlargement of an organ leads to acute pain e.g. renal colic
    • Slow enlargement of the organ causes long (chronic) pain E.g. hydronephrosis
    • assoc w/ N/V, => Involvment of vagus nerve
    • sharp pain
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3
Q

nature of pain in urology in relation to location

examples of localised pain tyoical for urological diseases

A

Acc may be located kidney→ ureter,→ urinary bladder,→ scrotum, penis,→ pelvis.

Location and type of pain in typical urological diseases

Acute

sharp/acute pain:

  • urinary stones=> urinary retention=> dilated fibrous capsule=>pain. not d/2 stone itself?
  • UTI=>

acute suprapubic pain in UB = Acute urinary retention => UTI=> CYSTITIS=> assoc w/ painful urination

acute scrotum= scrotal enlargement (swelling) and scrotal pain =>

  • torsion,
  • varicocele: dilatation and tortousity of the pampiniform plexus of veins and the internal spermatic vein.
    • left>right.
    • right side=advanced renal tumor(compression of right test veins)
  • hydrocele: liquid in scrotum
  • epididimitis/orchitis/epididimorchitis
  • renal colic= most common​=>violent peristaltic contraction of ureters
    • acute. intermittent, chronic
    • mins-hrs
    • migrates from Flank=>Loin=> Testes/Labia majora
    • pt appearanc in renal colic
      • hunched over w.o pain relief holding painful area
      • dry cracked lips and dehydrated d/2 n/v

chronic

Chronic suprapubic pain = Chronic urinary retention

large renal stone=> worsens w/ excercise. dx from acute renal colic

Chronic pelvic pain syndrome;

  • global problem in men and women.
  • MEN: the most common reason is chronic prostatitis,
  • women reason is painful urinary bladder lasting more than 6 months (chronic interstitial cystitis)
    *
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4
Q

why os varicocele more common on left

A

The angle at which the left testicular vein enters the left renal vein.

Lack of effective valves between the testicular and renal veins.

Increased reflux from compression of the renal vein (between the superior mesenteric artery and aorta). This is sometimes called the nutcracker syndrome or aorto-left renal vein entrapment syndrome[1].

https://m.blog.naver.com/PostView.nhn?blogId=jesus24968&logNo=221430224471&proxyReferer=https%3A%2F%2Fwww.google.com%2F

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5
Q

Cause of chronic pelvic pain syndrome in men

A

chronic prostatitis

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6
Q

Cause of chronic pelvic pain syndrome in women

A

interstitial cystitis charac by painful UB forover 6mo

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7
Q

classification for prostatic syndrome national institute of health of USA 1995 classification of prostatic syndrome.

A
  • catergory 1: acute bacterial prostatitis
  • category 2: chronic bacterial prostatitis
  • category 3: chronic pelvic pain syndrome
    • A: inflammatory B: Non inflammatory
  • category 3: asyx inflammatory prostatitis
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8
Q

upper uts according to google

A

pain and tenderness in the upper back and sides.

chills.

fever.

nausea.

vomiting.

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9
Q

list the lower urinary tract sx

A
  • storage sx(fun)
    • Frequency
    • Urgency
      Nocturia
  • voiding sx (rwshtop)
    • hesitancy
    • straining
    • prolonged urination
    • retention
    • overflow incontinence
    • terminal dribbling
    • weak urinary stream
  • post- voiding sx
  • incomplete voiding
  • dribbling
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10
Q

what is renal colic

how does the pt appear

A

renal colic= most common​=>violent peristaltic contraction of ureters

acute. intermittent, chronic

lasts mins-hrs

migrates from Flank=>Loin=> Testes/Labia majora

pt appearanc in renal colic

hunched over w.o pain relief holding painful area

dry cracked lips and dehydrated d/2 n/v

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11
Q

parasympathetic and sympathetic innvervation of the UB

A

Neurological control is complex, with the bladder receiving input from both the autonomic (sympathetic and parasympathetic) and somatic arms of the nervous system:

Sympathetichypogastric nerve (T12 – L2). It causes relaxation of the detrusor muscle, promoting urine retention.

  • α1a, (men)α2(women) located in the trigonum and in the urethra.
  • β1, β2 and β3-receptors.stimulation of β-receptors leads to the activation of adenylyl cyclase, to the release of cyclic AMP (cAMP) and to the inhibition of the detrusor muscle.

Parasympatheticpelvic nerve (S2-S4). Increased signals from this nerve causes contraction of the detrusor muscle, stimulating micturition.

  • M1, M2 (80%) and M3 (20%) cholinergic receptor types, but only M3 cholinergic receptors are responsible for the parasympathetic detrusor contraction. Stimulation of M3 receptors with acetylcholine causes the release of IP3 and calcium, which leads to smooth muscle contraction

Somaticpudendal nerve (S2-4). It innervates the external urethral sphincter, providing voluntary control over micturition.

In addition to the efferent nerves supplying the bladder, there are sensory (afferent) nerves that report to the brain. They are found in the bladder wall and signal the need to urinate when the bladder becomes full.

The Bladder Stretch Reflex

  • micturition is stimulated in response to stretch of the bladder wall. It is analogous to a muscle spinal reflex, such as the patella reflex.
  • During toilet training in infants, this spinal reflex is overridden by the higher centres of the brain, to give voluntary control over micturition.

The reflex arc:

Bladder fills with urine, and the bladder walls stretch. Sensory nerves detect stretch and transmit this information to the spinal cord.

Interneurons within the spinal cord relay the signal to the parasympathetic efferents (the pelvic nerve).

The pelvic nerve acts to contract the detrusor muscle, and stimulate micturition.

Although it is non-functional post childhood, the bladder stretch reflex needs to be considered in spinal injuries (where the descending inhibition cannot reach the bladder), and in neurodegenerative diseases (where the brain is unable to generate inhibition).

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12
Q

examples of diseases manifesting w/ dysuria

A

cystitis

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13
Q

disturbances in urination

what is dysuria

what is overflow incontinence

A

A. Dysuria = complex term containing three components.

  • 1. pollakiuria which is frequent urination. beyond 8x/ 24hrs
    • INTERNATIONAL CONTINENCE SOCIETY states that : Normal is 4-8/ 24h
    1. Algiuria = Painful urination Greek medical term.
    1. Stranguria = difficult urination

B. URINARY INCONTINENCE: consists of 4 parts (STUFed bladder)

  • Stress incontinence: d/2 increased P from excercise/ cough
  • True incontinence
    • active: detrusor overcomes sphincter contraction
    • passive: impaired sphincters=> bladder always empty
  • Urge incontinence: severe and sudden urge to urinate
  • False incontinence: bladder is always full, small amounts of urine

C. URINARY RETENTION: inability to void = distended bladder full of urine

  • etio: 1)mechanical 2)Neurogenic 3)Miscellaneous
  • TYPES of urinary retention
    • complete: can’t urinate at all
    • incomplete: small urination possible with residual urine in the bladder

D. OVERFLOW INCONTINENCE:

combo of urinary incontinence following urinary retention

  • bladder max vol = 300-400ml, after this urine overflows out of it
  • occurs in the following disease: BPH, STRICTURE,
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14
Q

what is dysuria

which body defines pollakuria

define the 3 components of dysuria

A

Dysuria = complex term containing three components.

  1. pollakiuria which is frequent urination. beyond 8x/ 24hrs

INTERNATIONAL CONTINENCE SOCIETY states that : Normal is 4-8/ 24h

  1. Algiuria = Painful urination Greek medical term.
  2. Stranguria = difficult urination
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15
Q

WHAT IS URINARY INCONTINENCE

A

B. URINARY INCONTINENCE: consists of 4 parts (STUFed bladder)

  • Stress incontinence: d/2 increased P from excercise/ cough
  • True incontinence
    • active: detrusor overcomes sphincter contraction
    • passive: impaired sphincters=> bladder always empty
  • Urge incontinence: severe and sudden urge to urinate
  • False incontinence: bladder is always full, small amounts of urine
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16
Q

what is urinary retention

causes of urinary retention

A

C. URINARY RETENTION: inability to void = distended bladder full of urine

etio:

1) mechanical : enlarged protate gland, stricture of urethra
2) Neurogenic: ispinal cord injury
3) Miscellaneous: tetanus

TYPES of urinary retention

  • complete: can’t urinate at all
  • incomplete: small urination possible with residual urine in the bladder
17
Q

define overflow incontinence

A

D. OVERFLOW INCONTINENCE:

combo of urinary incontinence following urinary retention

bladder max vol = 300-400ml, after this urine overflows out of it

occurs in the following disease: BPH, STRICTURE,

18
Q

descrrbe CHANGES IN VOIDED URINE

what are the two classifications of this kind of symptom

what are the 3 quantitative changes (poa)

what are the 5 qualitative changes( chspp

A

subdivided in two groups; qualitative and quantitative

Quantitative changes

  • Polyuria = urine output over 3L for 24h
  • Oliguria = <400 mL/day in adults
  • Anuria = <100 mL/day

Qualitative changes;

  • Hematuria = most common change in urine means RBC in urine. Always an alarming symptom . Predominantly it raises suspicion for malignancy.
  • Spermaturia = sperm in urine, reasonable explanation for this finding is retrograde ejaculation.
  • Pyouria pus in urine = enough to understand leukocytes in urine.
  • Bacteriuria = more than 10^5 cfu/ml (colony forming units, microbiology that estimates the number of viable bacteria in the urine) NB!!
  • Chyluria = lymph in urine. From surgical point of view, advanced stages of malignancies with blockage of lymph drainage. due to malaria, filaurosis
  • Crystaluria: stones in urine d/2 gout/ urolithiasis
  • Pneumaturia = air in urine = caused by fistula betw intestine and UT,
    • mc is vesicovaginal fistula
    • open surgical approach?
19
Q

who determines the qualitative changes in voided urine

A

classification of polyuria, anuria and oliguria is done according to INTERNATIONAL CONTINENCE SOCIETY

20
Q

Define anuria

A

complete abscence of urine (in the urinary bladder??)

classification of the causes of anuria

  1. pre-renal - DEHYD
  2. renal- bilat kidney stones
  3. post renal- bilat ureter compression, ligature of ureter, BPH, preg complications
21
Q

describe hematuria

what are the 3 types classifications of hematuria

why is it an alarming sx

A

def: RBC’s in urine (NOT BLOOD)
* ​classification 1: micro/ MACRO hematuria

  • classification 2: Real vs Pseudo.
    • psudo haematuria= Reddish urine that is not caused by blood in the urine
    • corrected by coagulation of blood
  • classification 3: time hematuria presents during voiding
    • Initial hematuria: beggining of urination d/2 urethral disorders
      • e.g: urethral trauma/ urethritis
    • Terminal hematuria: end of urination d/2 bladder & prostate disorders
      • bladder cancer, bladder trauma, cystitis, stones,
      • bph, prostate cancer
    • Constant/Total hematuria: during whole act
22
Q

can hematuria exist w/o a patholgoy

A

yes e.g.

  1. pregnancy
  2. weight training
23
Q

describe pyuria and what causes it

A

def: pus/ leukocytes in the urine

causes

  • urethritis
  • urosepsis
  • chronic prostatitis
  • pyelonephritis
    • ​sx: suprapubic pain +w/o urine for 12 hrs
      • dg: catheterization
        • no urine?= d/2 anuria
        • urine released in portions?: urinary retention
        • hematuria?: pyelonephritis?
24
Q

what are the genitosexual symptoms in urology

PM H E D G

A
  1. Gynecomastia
  2. Haemospermia( 50= Pca) (young= std)
  3. Disorders of ejaculation
  4. Erectile dysfunction
  5. Priapism: long lasting painful erection
  6. Male hypogonadism; • Male infertilityMetabolic syndrome
25
Q

what is hematospermia

what is the main cause of hematospermia in men over 50

A

def: blood in sperm

Main Reasons are prostate cancer, in men over 50 World wide Enough to know that example, etiology In young men not well understood?

26
Q

what is Gynecomastia

give 2 examples of diseases causing gynecomastia

A
  1. Klinefelter syndrome,
  2. testicular tumours;
    1. seminomatous / nonseminomatous germ cell tumour,
27
Q

most common suxual disorder in men?

definition according to WHO 2015

how is the degree of ED scored

how is ED rxed

A

2015 WHO DEF of Erectile Dysfunction: consistent or recurrent men’s inability to achieve and maintain an erection sufficient for satisfactory sexual activity.​

  • most common male sexual disorder along w/ premature ejaculation

assesment of ED done by:

international index of erectile function version 5

* 22-27= no ED * 5-7= severe ED

TYPES of ED according to etiology

  • Orgnanic:
    • compulsory complication 25-75% of cases radical prostatectomy for localised prostate cancer.
    • MC etio after surgery for penile fracture/carcinoma.
  • Psycogenic
  • Mixed

global consensus for treatment of ED

  • 1st line: phosphodiesterase 5 inhibitors (viagra).
  • 2nd line has 3 options
    • intracavernosal injections, of vasoactive drugs e.g. cavergen
    • _vacuum device_s.
    • intrauretral installations (prostaglandin E1)
  • 3rd line: penile prosthesis
28
Q

what are the Disorders of Ejaculation

what is the criteria for ejaculatory disorders based on normal sec

A

Normal sex 1-10 mins??

  1. Premature ejac: b4 1 min
  2. Delayed ejac: after 10 mins
  3. Retrograde ejac: sperm goes back causing spermaturia
  4. Full abscence of ejaculation = d/2 stenosis of prostate
29
Q

list the possible causes of ED

A
  • beta blockers
  • CDV diseases: cholesterol plaques in bv of penis
  • Chronic prostatitis & radical prostatectomy in 25-75%
  • Endocrine disorder: less testosterone, more estrogen, DB
  • Penile surgery after fracture
  • penile carcinomas
  • Neuurological cahses
    • MS, Stroke,
  • STRESS
30
Q

OVERACTIVE BLADDER OAB- what is OAB

what sx characterize this disease

A

clinical syndrome introduced in clinical practice in 2002, characterised by;

  • frequency beyond 12 times in 24 hours,
  • urgency (with or without incontincence) a type of incontinence is urgency incontinence,
  • nocturia more than 2 urinations during the night. according to INTL CONTINENCE SOCIETY
    • (most dangerous symptoms for patients and doctors
31
Q

what is the dx betw/ nocturia and oncturnal polyuria

A

nocturnal polyuria= This is more than 1/3 urine output for 24h voided urine between midnight and 8am.

Nocturia: more thran 2 urinations during the night

32
Q

describe the pathogenesis of OAB

A

parasympathetic bladder innvervation

  • there are 6 types of muscarinic receptors.
  • mediated by Ach
  • in the bladder wall, M2 and M3 predodminate
  • Activation of these receptors induce detrusor contraction. and urination
  • overactivation M2&M3// receptors causes excess contraction of detrussor= OAB

Sympathetic bladder innervation

  • beta 3 adrenoreceptors in bladder wa.
  • Mediated by NA.
  • Activation of B3AR cause detrusor relaxation
  • used as rx
33
Q

PHARMACOTHERAPY OF OAB

what is the course of the syndrome of OAB

what are the possible complications of OAB

A

usual treatment of OAB is anti muscarinic drugs

New start of the treatment of overactive is B3AR agonists

This syndrome is with Chronic clinical course, may last more than 10 years. •

Complications: may evolve to OAB with incontinence?

34
Q

Chronic pelvic pain syndrome;

A

global problem in men and women.

MEN: the most common reason is chronic prostatitis,

WOMEN: reason is painful urinary bladder lasting more than 6 months (chronic interstitial cystitis)

35
Q

summarise the sx of OAB in one sentence

A

LUT storage symptoms (FUN)