Urinary, Reproductive, Stress and Excercise Flashcards
The maintenance of normal body _______ levels is important for:
• maintaining normal cell volume
• normal function of the cardiovascular system
Fluid
retaining water a) blood pressure
eliminating water b) blood pressure
a) increases
b) decreases
Enzyme secretion (_______) results in water retention
Renin
many functions of the body are very sensitive to ___ therefore it must be maintained within strict homeostatic limits
pH
the kidneys play a key role in regulating the body’s _________ balance
acid-base
the kidneys regulate the body’s pH by excreting a) and reabsorbing b)
a) hydrogen ions (H+)
b) bicarbonate
Hormone secreted by kidneys that stimulates red blood cell production
erythropoietin (EPO)
Hormone secreted by kidneys that’s the active form of vitamin D
Calcitriol
An enzyme that activates the renin-angiotensin-aldosterone system (helps in the regulation of blood pressure and Na+ and K+ balance)
Renin
waste products from protein metabolism
ammonia and urea
waste product from the breakdown of hemoglobin
bilirubin
waste product from the breakdown of nucleic acids
uric acid
waste product from skeletal muscle
creatinine
With ____________, kidneys can produce and release glucose into the blood stream
hypoglycemia
The kidneys are located between vertebra a) and b), partially protected by ribs c) and d)
a) T12
b) L3
c) 11
d) 12
Superficial layer of the kidney
Renal cortex
Inner portion of the kidney
Renal medulla
The functional unit of the kidney
Nephron
the kidneys get ___% of resting CO
20-25%
Blood enters the kidney through the __________
Renal artery
A tangled ball-like network of capillaries within the kidney.
Glomerulus
At the level of the glomerulus, 1) in blood plasma are filtered through the 2), into the 3) (Bowman’s) capsule space and into the 4)
1) water and solutes
2) capillary walls
3) glomerular
4) renal tubule
__________ arteriole leads into the glomerulus
Afferent
Blood flows out of the glomerulus into the __________ arteriole
Efferent
The efferent arteriole leads to another capillary network – the _____________ capillaries
peritubular
The peritubular capillaries merge to ultimately form the _______ vein which leaves the kidney
renal
The fluid that enters the capsular space of the kidney is called the ________________
Glomerular filtrate
T/F: as filtered fluid moves along the renal tubule and collecting duc most of the water and useful solutes are reabsorbed and returned to the blood in the peritubular capillaries.
True
Wastes are drawn from the peritubular capillaries and are secreted into the fluid for removal from the body. What is this fluid called?
Urine
The amount of filtrate formed per minute in the kidneys. Indicator of kidney function.
Glomerular Filtration Rate (GFR)
T/F: increased GFR = increased urine production
True
In general, the body will regulate _______ by:
• adjusting blood flow into and out of the glomerulus
• altering the capillary surface area available for filtration
Glomerular Filtration Rate (GFR)
What mechanism is described below?
An increase in BP increases renal blood flow which increases GFR and stretches the walls of the afferent arterioles. This stretching triggers the contraction of smooth muscle in the walls of the afferent arterioles and vasoconstriction reduces blood flow and reduces GFR to previous level.
The myogenic mechanism (for Auto-Regulation of GFR)
What is described below?
An increase in BP increases renal blood flow which increases GFR and increases the Na+, Cl-, and water in tubular fluid. The increased Na+, Cl-, and water in tubular fluid triggers vasoconstriction of the afferent arteriole which reduces blood flow and decreases GFR to the previous level.
Tubuloglomerular feedback (for Auto-Regulation of GFR)
With increasing _______ activation, vasoconstriction of the afferent arteriole is greater which decreases GFR.
Sympathetic Nervous System
Strong vasoconstrictor hormone (both afferent and efferent), effective in reducing GFR.
Angiotensin II
Hormone released by the heart in response to atrial stretching (i.e. increased blood volume) which increases GFR.
Atrial natriuretic peptide (ANP)
5 hormones affect the ________ and _________ of water and ions by the renal tubules:
1) angiotensin II
2) aldosterone
3) ANP
4) ADH
5) PTH
Re-absorbtion and Secretion
Decreased BP -> kidneys secrete ______ (an enzyme)
Renin
Renin converts angiotensinogen (made by the liver) into _____________
angiotensin I
Angiotensin I is converted to angiotensin II at the lungs by _________________
angiotensin-converting enzyme (ACE)
Which hormone is responsible for the following:
• Decreased GFR (afferent arteriole vasoconstriction)
• Increased re-absorption of Na+ and Cl- ions and water
• stimulates the release of aldosterone
Angiotensin II