Urinary Flashcards

1
Q

Name the 3 main parts of the primitive kidney.

A

pronephric, mesonephric and metanephric

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2
Q

Which part of the mesoderm forms the urinary system?

A

intermediate mesoderm

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3
Q

which area doe sthe pronephros form?

A

cervical region

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4
Q

what does the urogenital ridge give rise to?

A

embryonic kidney and gonads

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5
Q

what sprouts the ureteric bud and what does the utereric bud become specifically?

A
  • mesonephric duct

- definitive kidney (collecting system portion)

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6
Q

what forms the excretory portion of the kidney?

A

metanephros (metanephric blastema)

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7
Q

where does the kidney first appear?

A

pelvic region

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8
Q

what is it called when the uereteric bud fails to interact with the intermediate mesoderm?

A

renal agenesis

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9
Q

what happens as a consequence of the ureteric bud splitting?

A

duplication of ureter (ectopic ureter)

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10
Q

what happens in multicystic kidney disease?

A

atresia of ureter

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11
Q

the urogenital sinus is created from the hindgut by the formation of what?

A

urorectal septum

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12
Q

the urogenital sinus is continuous with the umbilicus by what structure?

A

urachus

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13
Q

What is the remnant of the urachus?

A

median umbilical ligament

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14
Q

what is the difference between males and females when it comes to the mesonephric ducts?

A

in females, the MD regresses

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15
Q

what part of the urogenital sinus is the female urethra formed from?

A

pelvic part

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16
Q

which parts of the male urethra are formed by the pelvic part of the urogenital sinus and which from the phallic region?

A

pelvic-pre prostatic, prostatic, membranous

phallic-spongey

17
Q

what must happen in order for the spongy urethra to form?

A

genital tubercle must elongate and genital folds must fuse

18
Q

what is hypospadias?

A

defect in fusion of urethral folds

urethra opens onto ventral surface instead of the tip

19
Q

What is the equation to calculate the half life of a drug?

A

T1/2=(0.7 x Vd)/CL

20
Q

What is the equation for renal clearance?

A

Cs=(Us x Vs)/Ps

Us=urinary conc of solute
Vs=urinary flow rate
Ps=plasma conc of solute