Urinary Flashcards
Name the 3 main parts of the primitive kidney.
pronephric, mesonephric and metanephric
Which part of the mesoderm forms the urinary system?
intermediate mesoderm
which area doe sthe pronephros form?
cervical region
what does the urogenital ridge give rise to?
embryonic kidney and gonads
what sprouts the ureteric bud and what does the utereric bud become specifically?
- mesonephric duct
- definitive kidney (collecting system portion)
what forms the excretory portion of the kidney?
metanephros (metanephric blastema)
where does the kidney first appear?
pelvic region
what is it called when the uereteric bud fails to interact with the intermediate mesoderm?
renal agenesis
what happens as a consequence of the ureteric bud splitting?
duplication of ureter (ectopic ureter)
what happens in multicystic kidney disease?
atresia of ureter
the urogenital sinus is created from the hindgut by the formation of what?
urorectal septum
the urogenital sinus is continuous with the umbilicus by what structure?
urachus
What is the remnant of the urachus?
median umbilical ligament
what is the difference between males and females when it comes to the mesonephric ducts?
in females, the MD regresses
what part of the urogenital sinus is the female urethra formed from?
pelvic part
which parts of the male urethra are formed by the pelvic part of the urogenital sinus and which from the phallic region?
pelvic-pre prostatic, prostatic, membranous
phallic-spongey
what must happen in order for the spongy urethra to form?
genital tubercle must elongate and genital folds must fuse
what is hypospadias?
defect in fusion of urethral folds
urethra opens onto ventral surface instead of the tip
What is the equation to calculate the half life of a drug?
T1/2=(0.7 x Vd)/CL
What is the equation for renal clearance?
Cs=(Us x Vs)/Ps
Us=urinary conc of solute
Vs=urinary flow rate
Ps=plasma conc of solute
