Urinalysis Flashcards

1
Q

What does a basic urinalysis consist of?

A
  1. Visual inspection
  2. Chemical dipstick screening to look for blood, white cells, sugar, protein, and other substances
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2
Q

T/F: the dipstick may be read manually and automatically? What about the microscopic analysis?

A

True

Microscopic analysis: usually manually, but can also be automatic

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3
Q

If necessary, a microscopic analysis can be done to look for what three things?

A

Cells- dysmorphic rbc’s, wbc’s, shed epithelial cells

Casts- cell casts, matrix casts, waxy casts, granular, etc.

Crystals- uric acid, neutral, alkaline, abnormal

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4
Q

Red blood cells within the urine can come from any point along the urinary tract. Dysmorphic red blood cells are often a sign of of disease affecting the _______?

A

Glomerulus

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5
Q

Because it is the most concentrated, the _______ is often a preferred specimen for analysis…

A

“The first voided morning urine, because it is normally concentrated, is often the preferred specimen for urinalysis”

His response to my email

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6
Q

What two measurements reflect the concentrating ability of the kidneys?

A

Specific Gravity

Osmolality

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7
Q

After a period of dehydration, the osmolality should be ____ times that of plasma?

A

3-4 times that of plasma

(Had to email him to get this)

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8
Q

Proteinuria greater than ______ indicates nephrotic syndrome, but is occasionally seen in systemic diseases that affect the kidneys?

A

3.5 g/day

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9
Q

_____ can be seen in diabetic individuals?

It can also be seen in other states, such as ________ and ________?

A

Urine glucose

-pregnancy, endocrine disorders, pancreatic disorders

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10
Q

The ______ and _______ tests are used to help identify UTI’s?

A

Nitrite (reduced from nitrate by bacteria) & leukocyte esterase (measure of neutrophils)

-Positive results should confirmed by microscopic analysis of the urine and/ or culture

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11
Q

How long after a sample is collected should the urinalysis be performed?

A

2 hours or refrigerated

-24 hour specimens are unacceptable for UA testing

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12
Q

Why would you do a 24 hour urine test?

A

You avoid any momentary changes in urine….

  • You want to do urine protein electrophoresis
  • Urine electrolytes
  • Total protein
  • Hormones
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13
Q

T/F: you can see significant loss of function prior to rise in serum creatinine of BUN

A

True

-if their starting level is .5 they could lose half of kidney function and still be in normal limits

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14
Q

What condition/ substances are in the urine if it is yellow-green-brown? What about orange-red-brown? Pink-red? Dark brown-black?

A

Yellow-green-brown: bile pigments

Orange-red-brown: excreted urobilinogen

Pink red: hematuria, hemaglobinuria

Dark brown-black: methemoglobin, rhabdomyolysis

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15
Q

T/F: the dipstick method is only sensitive to one protein: albumin?

A

True

-So if you suspect other proteins (i.e. immunoglobulins) you need to do electrophoresis or total protein

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16
Q

What do oval fat bodies in a microscopic exam indicate?

A

Nephrotic syndrome

17
Q

What would waxy casts in a microscopic exam indicate?

A

Advanced chronic renal failure