Development of Kidney

Question 1

Watch this video: its really simple

Answer 1

https://www.youtube.com/watch?v=yigznAyhnGo (9min or 4.5 on 2x speed)

Question 2

What are the 3 “sets of kidneys” of kidney development?

Answer 2

1. Pronephros (3-4 wks)
2. Mesonephros (4wks- 2 months)
3. Metanephros (5wks- maturity)

Question 3

Where do the primitive kidneys “come from” embryologically?

Answer 3

Intermediate mesoderm–> urogenital ridge–> nephrogenic cord–> nephrotomes–> primative kidneys

Question 4

Which primative kidney grows caudally to join the cloaca?

Answer 4

Mesonephric duct (aka wolffian duct)

This will become MALE structures.

Remember the wolf cartoon caracter that would howl everytime he saw a hot chick?

Question 5

True or False:

The proneprhos is not a functional primative kidney and disintegrates after 4 weeks.

Answer 5

True

Question 6

T/F:
The metanephros is the main component of a functional mature kidney and is more well developed in land dwelling vertebrates.

Answer 6

True

Question 7

Where does the paramesonephric duct (mullerian duct) come from? What does it become?

Answer 7

Comes from an invagination of the coelom wall and becomes oviducts and uterus in females.

Question 8

The ureteric bud comes from the _______ duct, and is part of the developing _________ duct. The ureteric bud gives rise to the _______ system of the mature kidney.

Answer 8

The ureteric bud comes from the mesonephric duct, and is part of the developing metanephric duct. The ureteric bud gives rise to the _collecting system (ureter,
pelvises, calyces, collecting ducts and Collecting tubules)_ of the mature kidney.

See picture for illustration:

Question 9

True or false

The nephron is derived primarily from the ureteric bud.

Answer 9

FALSE:

Glomerulous through DCT is derived from the metaneprhic mesenchyme (aka metanephric blastema).

CT on is Ureteric Bud.

Question 10

What is the embryological origin of the urogenital sinus? What does the urogenital sinus give rise to?

Answer 10

Endoderm (from the cloaca)

Gives rise to the blader and urethra.

Question 11

What happens to the allantois and cloaca of the early embryo?

Answer 11

1. The allantois degenerates to form the urachus.
2. The cloaca (endoderm) gives rise to the urogenital sinus which gives rise to blader and urethra.

Question 12

Does the kidney ascend or descend into the abdomen?

Answer 12

Ascend