Upper GI disease

Question 0

What are the symptoms of chronic gastritis?

Answer 0

Upper abdominal pain
Bloating or indigestion
Nausea and vomiting
Belching 
Loss of appetite or weight loss

Question 1

What is chronic gastritis?

Answer 1

Ongoing inflammation of the stomach mucosa

Question 2

What can cause chronic gastritis?

Answer 2

Helicobacter pylori infection
Alcohol
Tobacco
Psychological stress
Caffeine
Autoimmune - can lead to pernicious anaemia

Question 3

What is H.pylori and where is it found?

Answer 3

Gram negative bacteria found in the stomach

Question 4

What is the clinical presentation of H.pylori?

Answer 4

80% asymptomatic 
5-15% peptic ulcer disease
10% non ulcer dyspepsia
1-3% gastric adenocarcinoma
0.5% gastric MALToma

Question 5

What is H.Pylori strongly associated with?

Answer 5

Chronic gastritis and duodenal ulcer

Question 6

Where does peptic ulcer disease usually occur?

Answer 6

D1 or Antrum

Question 7

What are common causes of peptic Ulcers?

Answer 7

H.pylori and NSAID’s

Question 8

What are the symptoms of peptic ulcers?

Answer 8

Pain - worse at night and worse after meals

Question 9

What happens in Barrett’s oesophagus?

Answer 9

Normal lining of the oesophagus replaced with columnar epithelium and goblet cells.

Question 10

What is Barrett’s oesophagus associated with?

Answer 10

Adenocarcinoma

Question 11

What are the types of cancer you can get in the oesophagus?

Answer 11

Squamous carcinoma

Adenocarcinoma

Question 12

What type of cancer can you get in the stomach?

Answer 12

Adenocarcinoma

Question 13

What type of cancer can you get in the small bowel?

Answer 13

Lymphoma
GI stromal tumours
Neuroendocrine tumours