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BIOM2009 > Upper GI > Flashcards

Upper GI Flashcards

1
Q

What is the role of gastric acid? How is it secreted

A

Secreted as H+ and Cl- via proton pump.
Works to denature proteins, allowing pepsin to metabolise them.
Kills pathogens due to low pH

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2
Q

Gastrin, acetylcholine and histamine all _____ gastric acid secretion

A

Increase

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3
Q

Somatostatin and prostaglandin ____ gastric acid secretion

A

Decrease

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4
Q

Antacids directly neutralise gastric acid. They provide symptomatic relief.
Name side effects of magnesium vs aluminium antacids

A 
Magnesium = diarrhoea 
Aluminium = constipation
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5
Q

Name 2 pro kinetic drugs

A

Metoclopramide and domperidone

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6
Q

What is the standard triple therapy treatment for H. Pylori infection?

A

Amoxicillin, clarithromycin and omeprazole

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BIOM2009 (13 decks)

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