Update on chemotherapy in gynaecological cancers 2016 Flashcards

1
Q

Difference mutations from 5 subtype of ovarian cancer

A
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2
Q

Main chemotherapy agents used in ovarian cancer

A

Carboplatin
Paclitaxel

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3
Q

Explain definition of platinum resistant, partially sensitive and sensitive in terms of time to relapse

A
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4
Q

Further response rate base on platinum free survival

A
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5
Q

What other drug can be given to those with BRCA mutation

A

PARP inhibitor

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6
Q

Explain type of endometrial cancer (T1 & T2)

A
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7
Q

Are uterine cancers responsive to chemotherapies?

A

T1 Endometroid cancers - yes
T2 no

Used to relapse

Carboplatin + paclitaxel

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8
Q

Which chemotherapy is typical used for cervial cancer

A

Cisplatin + radiotherapy

Recurrent: bevacizumab

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9
Q

What chemotherapy is used for vaginal & vulval cancer

A

Primary - radiation + cisplatin

Relapse Cisplatin + 5-FU

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