Update on chemotherapy in gynaecological cancers 2016 Flashcards
Difference mutations from 5 subtype of ovarian cancer
Main chemotherapy agents used in ovarian cancer
Carboplatin
Paclitaxel
Explain definition of platinum resistant, partially sensitive and sensitive in terms of time to relapse
Further response rate base on platinum free survival
What other drug can be given to those with BRCA mutation
PARP inhibitor
Explain type of endometrial cancer (T1 & T2)
Are uterine cancers responsive to chemotherapies?
T1 Endometroid cancers - yes
T2 no
Used to relapse
Carboplatin + paclitaxel
Which chemotherapy is typical used for cervial cancer
Cisplatin + radiotherapy
Recurrent: bevacizumab
What chemotherapy is used for vaginal & vulval cancer
Primary - radiation + cisplatin
Relapse Cisplatin + 5-FU