Endometrial cancer and obesity TOG 2019 Flashcards
1
Q
What is the most common gynaecological cancer in the UK?
A
Endometrial cancer
2
Q
For every additional 5kg/m2 what is the increased risk of endometrial cancer?
A
60%
3
Q
Lifetime risk of endometrial cancer if BMI 40?
A
10-15%
40% endometrial cancer diagnoses are attributed to weight
4
Q
Which hormones does adipose tissues contaainm which cancers androgens? What do they convert them to?
A
Aromatase
17b-HSD
Conver to estrone & Estadio
5
Q
Effect of high insulin on SHBG
A
Decrease in SHBG
Estrogen excess
6
Q
How much does regular phsical activity reduce risk of endometrial cancer?
A
20-30%
7
Q
What should be offered to young obese women to reduced risk of endometrial cancer
A
IUS
54% reduction in cancer risk
8
Q
Peak age of risk of endometrial cancer
A
7074%
9
Q
STOP BANG Q for obstructive sleep apnoea
A
