Gynae Oncology - Hereditary, Statistics Flashcards
1
Q
BRCA 1 - risk of breast and ovarian cancer by age 70?
A
BRCA 1
Breast: 85%
Ovarian: 63%
2
Q
BRCA 2 - risk of breast and ovarian cancer by age 70?
A
Breast: 84%
3
Q
Which type of cancers does BRCA 1 and 2 typically cause?
A
High grade serous and endometriosis carcinoma (papillary serous cystuadenocarcinoma)
4
Q
BRCA mutations are also at increased risk of which cancers?
A
Pancreatic, prostate, colon
5
Q
Lap BSO reduces the risk of ovarian cancer by how much for BRCA1/2 carriers?
A
80-96%
6
Q
BSO reduced the mortality in BRCA 1 & 2 by how much?
A
60-76%
7
Q
A
