Detecting endometrial cancer TOG 2021 Flashcards
What are the 2 strongest RF for endometroid EC
Age & obesity
Every 5kg/m2 increased risk EC
50%
Lynch syndrome risk EC?
25-60%
What proportion of EC present with PMB?
> 90%
What proportion of women with PMB have different cause other than EC
90%
Risk cancer with PMB if
<50 years
80 years
<50 years <1%
>80 years 24%
Table from passMRCOG risk of EC >80, <50, obese, DM, obese and DM
When to refer if bleeding on HRT
> 6months agter starting
6weeks after stopping
Diagnostic pathway for PBM
Sensitivity & specificity of ET >4mm & 5mm
4mm
95% sensitivity
46% spec
5mm
96 sensitivity
51 specificity
Asymptomatic women, risk EC if ET >11 or < 11mm
> 11 6.7%
<11 0.002%
Failure rate, inadequate sample of endometrial biopsy. Sensitivity
Failure 11%
Inadequate sample 31%
Sensitivity 90%
OP Hysteroscopy sensitivity and specificity
Failure rate
86%
92%
Failure 4%