UNIT 9 PEDIATRIC ONCOLOGY Flashcards
Side effects of cancer
Infection
Hemorrhage
Anemia
Nausea/vomiting
Altered nutrition
Mucosal ulceration
Neurologic problems
Hair loss
What is the definition of leukemia?
A. Malignant diseases of bone marrow and lymphatic system
B. long bone cancer
C. Cancer in eye
D. Cancer in nephrons
A. Malignant diseases of bone marrow and lymphatic system
Which type of Leukemia is most common
ALL- Acute Lymphocytic Leukemia
or
AML – Acute Myelogenous Leukemia (acute
ALL- Acute Lymphocytic Leukemia
Most common type of childhood cancer
Peak onset: 2-5 years
AML – Acute Myelogenous Leukemia (acute
nonlymphoid)
20% of leukemia cases
Higher rates seen in infants
S/S of leukemia
Manifestations
Anemia
Infection
Bleeding
Enlarged organs
Fever, lethargy, malaise
Petechiae
Weight loss
Diagnostic of Leukemia
Peripheral blood smear
Bone marrow aspiration
LP
IS there stages where leukemia is treated
Yes
No
Induction phase
Begins at diagnosis, lasts 4-5 weeks
Intensification therapy
Further decreases leukemia cells in body
“pulses” of chemo over 6 months
Maintenance therapy
Combined drug regimen to keep in remission
Used for 2-3 years
What i the final stage of treatment is leukemia isn’t treated by chemotherapy
Bone marrow transplant
Reserved for poor response to chemotherapy
You just received a new admission. The child is diagnosed with Leukemia . What room assignment owed be most appropriate for this patient?
A. droplet precautions two bed
B. Airborne precaution - negative air flow room
C. Private room one bed
D. Contact precaution double room
C. Private room one bed
Private room
Hand hygiene
No sick visitors
What is Neuroblastoma ?
(STOMACH CANCER)
Most common cancer
diagnosed in infancy
Primary site: abdomen
“silent” tumor- poor
prognosis
Often mestataizes
S/S of Neuroblastoma(
- Firm, nontender, irregular mass in the abdomen that crosses the midline
- Urinary frequency or retention from compres-
sion of the kidney, ureter, or bladder - Lymphadenopathy, especially in the cervical and
supraclavicular areas - Bone pain if skeletal involvement
- Supraorbital ecchymosis, periorbital edema, and
exophthalmos as a result of invasion of retrobul-
bar soft tissue - Pallor, weakness, irritability, anorexia, weight loss
- Signs of respiratory impairment (thoracic le-
sion) - Signs of neurological impairment (intracranial
lesion) - Paralysis from compression of the spinal cord
Neuroblastoma treatment
Treatment
Surgery, chemo
What is osteosarcoma?
Most common bone tumor, arises from osseous tissue
BONE CANCER (TUMOR)
Peak age 15 years; boys > girls
Most commonly found in the metaphyseal region of long
bones in lower extremities
Symptoms in the earliest stage are almost always attributed to extremity injury or normal growing pains.
S/S OF OSTEROSARCOMA
Pain at the affected site- SEVERE or dull
Limps; may interfere with normal activity
Progressive limited range of motion and the child’s curtailing of physical activity’
Child may be unable to hold heavy objects because of their weight and the resultant pain in the affected extremity.
Pathological fractures occur at the tumor site.
May have a palpable mass
Symptoms in the earliest stage are almost always attributed to extremity injury or normal growing pains. (MAY BE MISTAKEN FOR GROWTH SPURTS)
Treatment of Osteosarcoma
Treatment may include surgical resection (limb salvage procedure) to save a limb remove affected tissue, or amputation.
- Chemotherapy is used to treat the cancer and may be used before and after surgery.
What is Ewing Sarcoma
Arises from the marrow
Originates in the shaft of long bones in extremities and trunk
Almost always occurs in people younger than 30 years of age
(long bone cancer)