Unit 8 Flashcards
Isotonic Solutions Percent Salt:
0.9% NaCl
Isotonic Solutions Other names
- D5W (5% dextrose)
- Saline, NS, PS, PSS
- Ringer’s
- Lactated Ringer’s
- Milliosmoles: 300 milliosmoles/Liter (mOsm/L)
- Milliequivalents: 325 milliequivalents/Liter (mEq/L)
Hypertonic Solutions Percent Salt:
> 0.9% NaCl
- Milliosmoles: >300 milliosmoles/Liter (mOsm/L)
- Milliequivalents: >325 milliequivalents/Liter (mEq/L)
Hypertonic Solutions other name
D10W (>5% dextrose)
Hypotonic Solutions Percent Salt
<300 milliosmoles/Liter (mOsm/L)
Hypotonic Solutions other name
D2W (<5% dextrose)
Definition of osmosis
H2O moves toward the region of higher solute concentration
Isotonic Solution movement:
- causes no net water movement (cell is in equilibrium)
- cells in an isotonic solution show no change in size & function
Hypertonic Solution movement:
- draws H2O out of the cell
- cells crenate in a hypertonic solution; size + function both decrease
Hypotonic Solution movement:
- draws H2O into the cell
- cells in a hypotonic solution swell & may lyse; size increases, function decreases
Blood sodium levels drop from 325 mEq/L to 124 mEq/L
What is the danger?
-↓Sodium in the blood allows H2O to move into cells (osmosis)
-Less fluid in blood
-↓Blood volume
-↓Blood pressure
To correct this:
↑Heart rate will ↑blood pressure
What does electrolytes ionize into?
particles
Ex: NaCl –> Na+ + Cl-
Does glucose ionize?
Nonelectrolytes (Glucose), do not ionize
Organs That Regulate Fluid & Electrolyte Balance:
Brain, Adrenal Glands, Kidneys
List the steps of the thirst mechanism
DECREASED ECF VOLUME OR INCREASED ECF OSMOLALITY —>HYPOTHALAMUS—-> ↓SALIVA —->THIRST—>DRINK—>↑ ECF VOLUME
About Aldosterone
-Hormone (mineralocorticoid)
-Secreted by: adrenal cortex
-Stimulates kidneys to:
Reabsorb Na+, Cl–, H2O
Secrete K+
Estrogen
- Female hormone from the ovaries mimics aldosterone
- Stimulates kidneys to reabsorb sodium, chloride, water
- ↑Fluid retention (edema)
How does estrogen affect calcium?
Calcium Moves Into Bone
Cortisol
- Hormone (glucocorticoid) from the adrenal cortex that mimics aldosterone
- Converts lipids & protein to glucose (gluconeogenesis)
- Anti-inflammatory (vasoconstrictor)
What does ↑Cortisol causes:
Edema, ↑visceral fat deposition, ↓memory storage, ↓memory retrieval
What does Antidiuretic Hormone (ADH) do?
Saves water at the collecting duct
Calcitonin Increases! In which direction will calcium move?
blood —> bone
Parathyroid Hormone Increases! In which direction will calcium move?
bone —> blood
A person is in the hot sun for many hours resulting in water lost through perspiration
How does the body maintain homeostasis?
- Hypothalamus makes ↑Aldosterone & ↑ADH
- Kidneys produce ↓urine
- Hypothalamus will cause ↑thirst (thirst center)
A person urinates many times during the day but is able to sleep all night w/o the need to urinate
How is this explained?
Hypothalamus secretes ↑ADH during sleep (↑ADH prevents urination)
A person has had diarrhea for two days
Body potassium level is only 25% of normal value
Why is potassium level so low?
- Body has lost fluid & w/ this fluid, has lost potassium
- Patient must be given potassium immediately or the heart may develop arrhythmias (stop efficient pumping)
A patient has been unable to eat anything following surgery
The physician has ordered an IV of D5W
Why was this done?
- Fluid in the D5W will replace fluid that will naturally be lost due to not eating
- Dextrose (glucose) will provide an energy source for the body
Dr. Feelgood has told a patient that they need to flush the toxins & poisons out of their body
The patient has been given an IV of distilled water twice a week
What are the risks to the patient w/ this treatment?
- Distilled water is hypotonic to cells
- Red blood cells will lyse & release hemoglobin, creating a burden on the liver to cleanse the blood
- ↓Red blood cell count could make the patient anemic
A patient has had severe head trauma & there is swelling around the brain
The physician has ordered an IV of 20% glucose (D20W)
Why was this done?
20% Glucose is hypertonic
It will attract fluid from the brain into the blood, reducing the swelling around the brain
A patient has a history of hypertension
The physician has placed the patient on a ↓sodium diet
What is the reason for the ↓sodium diet?
- Salt makes the blood hypertonic
- Fluid will move by osmosis into the blood
- ↑Blood volume → ↑blood pressure
- Sodium ↑BP in ⅓ of patients (sodium sensitivity)