Unit 6: Water and Minerals Flashcards
which nutrient do we need the most
water
how long can you survive without water
- few days
describe the functions of water in the body (7)
- carries nutrients & waste products throughout the body
- maintains the structure of large molecules
- participates in metabolic rxns
- solvent
- maintains blood volume
- regulates body temp
- acts as a lubricant & cushions
list 2 large molecules that water helps maintain the structure of
- proteins
- glycogen
what does water serve as the solvent of (4)
- minerals
- vitamins
- amino acids
- glucose
how does water aid in the regulation of normal body temp
- evaporation of sweat from the skin removes excess heat from the body
what does water act as a lubricant for (4)
- around joints
- in the eyes
- spinal cord
- amniotic sac surrounding a fetus
how is water excretion regulated (3)
- by the brain & kidneys thru:
- ADH
- renin
- aldo
a healthy body excretes a minimum of how much water daily? why
- 500 mL
- sufficient to clear metabolic waste
what do water requirements depend on
- size
- enviro
- activity
- etc.
what is the AI of water intake for men? women?
- men = 3.7 L
- women = 2.7 L
what can imbalances of water intake and excretion cause (2)?
- dehydration
- water intoxication
what is the role of the hypothalamus in water intake
- mediates thirst & the urge to drink
- which is based on the conc of blood with solutes
how does thirst change with age
- sensation of thirst decreases
list 3 sources of water
- liquids
- foods
- metabolic water
list 4 sources of water loss
- kidneys (urine)
- skin (sweat)
- lungs (breath)
- GI tract (feces)
what is considered mild dehydration
- loss of <5% body weight
what is considered severe dehydration
- loss of >5% body weight
list signs of mild dehydration (lotssss, 13)
- thirst
- sudden weight loss
- rough, dry skin
- dry mouth, throat, body linings
- rapid pulse
- low bp
- low energy/weakness
- impaired kidney function
- reduced quanity & concentrated of urine
- decreased mental functioning
- decreased muscular work
- fever
- fainting
list signs of severe dehydration (9)
- pale skin
- bluish lips & fingertips
- confusion/disorientation
- rapid, shallow breathing
- weak, rapid, irreg pulse
- thickening of blood
- shock
- seizures
- coma, death
what organ plays an important role in fluid, electrolyte balance, and acid-base
the kidneys
what is the importance of fluid & electrolyte balance (2)
- maintains water conc
- prevents edema
- and others
list 6 causes of fluid & electrolyte imbalance
- vomiting
- diarrhea
- heavy sweating
- fever
- burns
- wounds
what are minerals
- naturally occurring, inorganic, essential, chemical elements
what are considered major minerals
- minerals found in the body in amts larger than 5 g
what are considered trace minerals
- minerals found in the body in amts less than 5 g
list 7 examples of major minerals
- calcium
- chloride
- magnesium
- phosphorus
- potassium
- sodium
- sulfur
list 9 examples of trace minerals
- chromium
- copper
- fluoride
- iodine
- iron
- manganese
- molybdenum
- selenium
- zinc
how are major minerals expressed
- in mg or grams
how are trace minerals expressed
- mg or micrograms
describe the requirement for major & trace minerals
- both are needed, but in diff amounts
what are shortfall nutrients
- nutrients that tend to be deficienct in many people
list 4 examples of shortfall nutrients
- calcium
- magnesium
- iron
- potassium
which nutrients is often overconsumed
- sodium
what is sodium
- a positievly charged ion that is used to maintain the volume of fluid outside cells
- major mineral
what is the DRI recommendation for sodium? what does the average canadian consume?
- DRI = 1500 mg
- average = over 2700
list the functions of sodium (4)
- primary regulator of ECF
- essential to muscle contraction
- nerve transmission
- helps maintain acid-base balance
list food sources of sodium (3)
- salt
- soy sauce
- processed foods
list symptoms associated with sodium deficiency (3)
- muscle cramps
- mental apathy
- loss of appetite
what is a sign of sodium toxicity
- HTN
see box 9-1 in the notes for strategies to cut salt intake
- kinda obvious tho
what can lead to HTN
- high intakes of sodium
world-wide, populations with high salt intakes experience higher rates of… (3)
- HTN
- CVD
- cerebral hemorrhage
what is one proven dietary approach to help people lower than Na intake & increase their K intake
DASH diet
what does the DASH diet encourage
- diet that encourages potassium rich foods
- whole grains
- fruits & veggies
- nuts
- poultry
- fish
- fat free or low fat milk products
what does the DASH diet discourage
- red & processed meats
- sweets
- sugar containing drinks
what is another strategy to that helps lower BP
- regular physical activity
what is another benefit of the DASH diet
- can lower LDLs = cardioprotective
what are other tips for individuals on the DASH eating plan (5)
- keep active
- stay within alcohol limits
- quit smoking
- lower stress lvls
- adhere to BP meds
describe how the DASH diet plan works
- suggests a certain # of servings from each food category based on 3 different calorie lvl diets
what is chloride
- a major negative ion
what are the fnxns of chloride (3)
- accompanies sodium in the fluids outside the cells
- helps maintain fluid & electrolyte balances
- maintains acid-base balance
what is chloride a part of? what role does this have?
- part of hydrochloric acid (HCl)
= maintains the strong acidity of the stomach
= necessary for proper digestion
describe chloride deficiency
- does not occur under normal circumstances
describe chloride toxicity (2)
- normally harmless
- can cause vomitting
list food sources of chloride (4)
- main source is salt
- soy sauce
- moderate amts in whole, unprocessed foods
- large amts in processed foods
what effect does dehydration on potassium
- causes the loss of potassium from inside cells
why is the loss of potassium from cells dangerous
- once cells of the brain lose potassium, they lose the ability to detect the need for fluids
what impact does the relationship between dehydration & K+ have on the administration of diuretics
- only take under dr supervision
- and the pt should be encouraged to eat potassium rich foods to compensate for losses
list food sources of potassium (7)
- fresh, whole foods
- veggies
- fruits
- legumes
- meats
- milk
- grains
what effect does processing have on K+
- processing causes potassium loss
what impact does K have on BP
- low K+ intake can cause HTN
- high K+ intake can prevent or correct HTN
what is the main fnxn of potassium (5)
- maintains fluid & electrolyte balance
- cell integrity
- role in nerve transmission
- muscle contraction
- critical for heart function
what are signs of moderate K+ deficiency (4)
- elevated BP
- increased salt sensiivity
- increased risk of kidney stones
- increased bone turnover
what are signs of severe K+ deficiency (3)
- cardiac arrhythmias
- muscle weakness
- glucose intol
what are signs of K+ toxicity (3)
- muscle weakness
- trigger vomitting
- if given into a vein, can stop the heart
how long does active bone growth occur
from birth to ~ age 20
who is the DRI recommendations for calcium higher in? why?
- children & adolescents
- to help achieve peak bone mass
what is osteoporosis
- reduction in bone mass where the bones become porous & fragile
osteoporosis is a result of…
- result calcium deficiency
who is osteroporosis more common in? why? (3)
- women
- less calcium in diet
- loss after menopause
- lower bone mass from the start
what does osteoporosis cause later in life
- fractures
list nonmodifiable risk factors for osteoporosis (8)
- female
- older age
- small frame
- caucasian, asian, hispanic/latino heritage
- FHx
- personal history of fractures
- estrogen deficiency in women
- testosterone deficiency in men
list modifiable factors of osteoporosis (7)
- sedentary lifestyle
- inadequate calcium & vitamin D
- excessive sodium & caffeine
- alcohol abuse
- smoking
- low body weight
- certain med
list 2 meds that are a risk factor for osteoporosis
- glucocorticoids
- anticonvulsants
what is the most abundant mineral in the body
- calcium
where is most of calcium stored?
- bones
- teeth
- 1% in fluids inside and outside of cells
what do blood calcium lvls look like during osteoporosis? why?
- will never appear low
- if diet is not adequate in calcium, the body will maintain blood calcium lvls by taking calcium from the bones
= osteoporosis
what are the roles of the calcium in body fluids (7)
- transport of ions across cell membranes
- nerve transmission
- maintain normal bp
- role in clotting blood
- muscle contraction –> heartbeat
- secretion of hormones, digestive enzymes, nt
- activates cellular enzymes
what are signs of calcium deficiency symptoms
- stunted growth in children
- adult bone loss (osteoporosis)
what are signs of calcium toxicity symptoms (4)
- constipation
- increased risk of kidney stone formation
- kidney dysfunction
- interference w absorption of other minerals
list food sources of calcium
- milk & milk products
- oysters
- small fish (w bones, like sardines & salmon)
- tofu
- some leafy greens
- legumes
- calcium fortified juices
- fortified soy beverages
describe the role of spinach & swiss chard with calcium
- contains binders which make them poorly absorbed
what is a factor that affects calcium absorption
- vitamin D deficiency
what is the second most abundant mineral in the body
- phosphorus
what is phosphorus commonly bound to
- calcium as part of bone
what is the fnxn of phosphorus (4)
- mineralization of bones & teeth
- important in cells’ genetic material (DNA and RNA)
- in cell membranes as phospholipids
- in transfer & buffering systems
list food sources of phosphorus
- dairy products
- animal products (beef, fish, poultry, eggs)
- legumes
describe phosphorus deficiency
- unknown
- the body’s needs for phosphorus is easily met by almost any diet
describe symptoms of phosphorus toxicity
- calcification of nonskeletal tissues
- particularly the kidneys
where is over half of magnesium stored? what does this mean?
- in bones
= when blood lvls are low, the body can borrow from the bone stores of magnesium
what else works to conserve magnesium
- kidneys
what is the fnxn of magnesium (6)
- critical for enzyme functions
- create proteins
- release energy
- works w calcium in muscle contraction
- bone mineralization
- nerve impulse transmission
list symptoms of magnesium deficiency (3)
- low blood calcium
- muscle cramps
- confusion
what are signs of severe magnesium deficiency
- seizures
- bizarre movements
- hallucinations
- difficulty in swallowing
- in children = growth failure
what are signs of magnesium toxicity
from nonfood sources:
- diarrhea
- nausea
- abdominal cramps
- acid-base imbalance
- potassium depletion
list food sources of magnesium
- nuts
- legimes (ex. black beans)
- whole grains
- dark green veggies (ex. spinach)
- seafood
- chocolate & cocoa
describe the effect of processing on magnesium; what indication does this mean
- easily washed & peeled awar from foods during processing
= whole foods are better sources
magnesium deficiency may be related to… (4)
- CVD
- heart attacks
- HTN
- may increase the risk of disease development
what causes magnesium toxicity
- non-food sources such as supplements or magnesium salts
what are the fnxns of sulfate
- synthesis of sulfur-containing compounds
- part of the hormone insulin
list examples of sulfur-containing examples
- amino acids that form protein in skin, hair, and nails
- antioxidants
- B vitamins (biotin & thiamin)
describe sulfate toxicity
- would only occur is sulfar amino acids were eaten in excess
what are food sources of sulfate
- protein containing foods:
- meat
- fish
- poultry
- eggs
- milk
- legumes
- nits
describe sulfate deficiency
- none known
- protein deficiency would occur first
where is iron stored & where is it sent to? what does it make?
- stored in the body in the bone marrow
- sent to the liver where it is packed into RBC & sent to the bloodstream
what happens when RBC die
- spleen & liver break them down, salvage the iron, and send the iron back the bone marrow for storage
what can extreme iron deficiency result in
- iron deficiency anemia
what is the most common nutrient deficiency
- iron deficiency
list symptoms of iron deficiency
- anemia
- weakness
- pallor
- HA
- reduced work productivity
- inability to conc
- impaired cognitive function
- lowered cold tolerance
- pica
what are the fnxns of iron in the body
- part of the protein Hgb
- part of the protein myoglobin
- necessary for utilization of energy
what is the fnxn of hgb
- carries O2 in the blood
what is the fnxn of myoglobin
- makes O2 available for muscle contraction
what is pica
- craving dirt
why does pica occur with iron deficiency
- bc the body is craving iron
- some soils contain iron
describe iron toxicity
- iron is toxic in large amounts
- once it is absorbed into the body, it is difficult to get rid of
how does the healthy body protect itself from iron toxicity
- by controlling iron’s entry
what is iron overload called?
- hemochromatosis
what occurs with hemochromatosis
- lrg genetic component
- the intestinal tract continues to absorb iron at a high rate, despite the excess iron build up in body tissues
list the early symptoms of iron toxicity (3)
- fatigue
- mental depression
- abdominal pain
list late symptoms of iron toxicity
- tissue damage
- liver damage
- abnormal heart beats
- acidosis
- bloody stools
- shock
- infections
is food often fortified w high lvls of iron
- no, bc of the symptoms of liver toxicity
describe the relation between iron & calcium
- calcium can make ur body absorb more iron
list food sources of iron
- red meat
- fish
- poultry
- shellfish
- eggs
- legumes
- dried fruit
- enriched & whole grain products
- dark green leafy veggies
iron supplements are the leading cause of??
- fatal, accidental poisonings among canadian children under 6 years old
what 2 populations require a higher DRI for iron
- women
- vegetarians
why do women require a higher DRI for iron
- bc of menstruation
why do vegetarians require more iron
- bc iron in plant foods is not as well absorbed as iron in animal foods
- need 1.8 x the amt of iron reccomended for the general population
see the notes for tips on how to stay healthy w iron intake
too long for cards
what are the 2 forms of iron
- heme
- nonheme
what is heme iron
- iron bound to heme
- the iron containing part of hgb and myoglobin in meat, fish, and poultry
describe the absorption of heme iron
- more readily absorbed
- absorb about 23% of heme iron from animal sources
what is nonheme iron
- found in plant foods and in the nonheme iron in meats
describe the absorption of nonheme
- people absorb about 2-20% of nonheme iron
what can increase nonheme iron absorption
- eat it w meat, fish, or poultry
- eat it w vitamin C
list 3 substances that inhibit iron absorption
- tannins
- calcium & phosphorus in milk
- phyates
where are tannins found in
- tea & coffee
where are phyates found
- accompany fibre in whole grains and legumes
list dietary recommendations for an individual with hemochromatosis (3)
- consume milk, tea, or coffee w meals to help inhibit iron absorption (contains calcium & tannins)
- avoid consuming vitamin C rich foods with meals
- limit consumption of meat, fish, poultry
list the dietary recommendations for an individual w anemia
- consume vitamin C or meat, fish, or poultry (increases the absorption)
- avoid milk, tea, or coffee w meals
what is the fnxn of zinc in the body
- works w proteins in every organ
- helps activate 50 enzymes
- vitamin metabolism (creates vitamin A)
- taste perception
- wound healing
- making of sperm
- normal fetal development
- immune rxns
- part of the hormone insulin
list symptoms of zinc deficiency
- growth impairment
- immune system impairment
- affects digestive fnxn
- vitamin deficiency symptoms
- disturb normal thyroid fnxn
- delayed sexual maturation
- loss of taste
- poor wound healing
- eye & skin lesions
describe the effect of zinc deficiency in pregnant women
- can lead to problems w growth & development of the fetus
what are some vitamin deficiency symptoms seen in zinc deficiency (2)
- abnormal taste
- abnormal night vision
what symptoms are seen during zinc deficiency r/t to disturbed thyroid function
- slowed metabolic rate
- loss of appetite
- slowed wound healing
list symptoms r/t zinc toxicity
- loss of appetite
- impaired immunity
- death
- block copper absorption
- iron deficiency
- NVD
- HA
what can cause zinc toxicit
- when zinc supplements are taken
at high doses, zinc may cause..
- reduced HDL
- impaired iron absorption
(only in suplements)
list food sources of zinc
protein-containing foods
- meats
- fish
- shellfish
- poultry
- grains
- veggies
- milk products
when is zinc best absorbed?
- from animal products
what helps increase absorption of zinc
- cereals enriched w zinc & whole grain breads which contain yeast
how does yeast increase the absorption of zinc
- yeast breaks down phytates, which binds zinc
- breaking down phyates makes zinc more available for absorption
what is the fnxn of selenium
- antioxidant
- enzymes containing selenium are needed for proper functioning of iodine-containing thyroid hormones
what does selenium deficiency cause
- keshan disease
what is keshan disease
- heart disease in children & young women
- causes cardiac tissue to become fibrotic
describe selenium toxicity
- toxic in large quantities
list symptoms of selenium toxicity
- vomitting
- diarrhea
- loss of hair & nails
- lesions of the skin & nervous system
list food sources of selenium
- meats / organ meats
- seafood
- grains
- veggies (depending on the selenium content of the soil they were grown in)
what is the fnxn of iodine
- component of 2 thyroid hormones, which help regulates metabolic rate, growth, reproduction, body temp
what happens when iodine is deficient
- cells in the thyroid gland enlarge, attempting to trap more particles of iodine
- the cells can grow large enought o product a lump on the neck = gioter
list symptoms associated with iodine deficiency
- goiter
- sluggishness
- weight gain
what happens if a woman that is pregnant is severely deficient in iodine?
- cretinism in the infant
what is cretinism
- extreme & irreversible mental and physical impairment in the infant
how can cretinism be prevented
- if the deficiency is discovered treated within the first 6 months of pregnancy
what can excessive intakes of iodine cause
- enlargement of the thyroid galnd (goiter like)
- deadly poison in large amts
list sources of iodine
- iodized salt
- seafood (plentiful in the ocean)
- bread (additive in bakery products)
- amt of iodine in food varies based off soil that the plants are grown in or in which the animals grazed
where is soil found that is rich in iodine
- where the ocean used to cover
how iodized salt is required per day to prevent iodine deficiency
- 1/2 tsp
what is the fnxn of copper
- enzymes
- wound healing
- manufacturing collagen
- forming hgb
- maintaining myelin sheaths
- helps cells use iron
list symptoms of copper deficiency (2)
- anemia
- bone abnormalities
list symptoms of copper toxicity (3)
- vomitting
- diarrhea
- liver damage
list food sources of copper
- organ meats
- seafood
- nuts & seeds
- whole grains
- drinking water
what is the fnxn of manganese
- works w enzymes as a cofactor, for many cell processes
- bone formation
describe deficiency of manganese
- rare bc only require little amt
describe toxicity of manganese
- very severe
list symptoms of manganese toxicity
- brain disease & nervous system disorders
- abnormalities in appearance and behavior
list food sources of manganese
- nuts
- whole grains
- leafy veggies
- tea
what is the primary role of fluoride
- inhibit the development of dental carries in adults & children
- element involved in formation of bones & teeth
what are ways that we help increase intake of fluoride
- add to drinking water
- in toothpaste & mouthwash products
what is dental flourosis
- condition that changes the way ur tooth enamel looks
- causes small white spots on adult teeth
what causes dental fluorosis
- ingesting too much fluoride while a child & permanent teeth are developing under the gums
at what point can you not get dental fluorosis
- if your adult teeth have grown in
how is dental fluorosis classified
- according to the level of severity
- from normal to severe
what is skeletal fluorsis
- hardening of the bones & jones
- weak, malformed bones
what causes skeletal fluorosis
- ingesting very high lvls of fluoride every day for a long period of time
- high amt of fluoride in the bones
is fluoride safe for pregnant/breastfeeding women & kids?
- yes
list 3 ways to avoid excess fluoride
- rice grain sized amt of toothpaste for 1-3 years
- green pea for 3-6
- six & up can swallow
what is the optimal lvl of fluoride in water
0.7 mg/L
what does the optimal lvl of fluoride in water take into account
- fluoride we get from other sources
ex. toothpaste or mouthwash
describe fluoride in ground water & its indications
- occurs naturally in the enviro & groundwater = may contain fluoride lvls above optimal lvl
- if getting water from well, get water tested regularly
what is a symptom of fluoride deficiency
- susceptibility to tooth decay
list sources of fluoride (4)
- drinking water
- toothpaste
- seafood
- tea
what if the fnxn of chromium
- role in how the body metabolizes carbs & fats
which hormone does chromium work closely with? what indication does this have
- insulin
- problems w BG regulation occur when chromium is lacking
what are symptoms of chromium deficiency
- diabetes like condition mark by inability to use glucose normally
describe chromium toxicity symptoms
- none reported
list 2 sources of chromium
- meats
- liver
- nuts
- cheese
- brewer’s yeat
- fruits
- veggies
- whole grains
list 5 trace minerals
- molybdenum
- nickel
- silicon
- cobalt
- boron
what is the fnxn of molybdenum
- working part of several metal containing enzymes
what is the fnxn of nickel
- promotes healthy body tissue
what does nickel deficiency cause
- damages the liver
what is the fnxn of silicon
- helps from bones & collagens
what is the fnxn of cobalt
- part of vitamin B12 molecule
what is the fnxn of boron
- influences activity of enzymes
- plays key role in bone, brain, and immune health