Unit 6 Flashcards
Pulmonary Circulation
to and from the capillaries of the lungs. Brings deoxygenized blood to the lungs, and returns oxygenated blood to the heart
Systemic Circulation
To and from the capilaries of the tissues of the body. Brings oxygenated blood to the tissues and returns deoxygenated blood to the heart
What is Edema
(AKA - Dropsy) A shift of fluids from vascular space into another compartment that results in abnormal accumulation of fluid in tissues or body cavities.
What is Anasarca
Severe, generalized edema of subcutaneous tissue, accumulation of serous fluid in body cavities
What is Ascites
Form of anasarca where fluid is in the abdominal (peritoneal) cavity
What is Hydrothorax
Form of anasarca where fluid is in the thoracic (pleural) cavity
What is Hydropericardium
A form of anasarca where fluid is around the heart
What is Hydrocele
A form of anasarca where edema is in the scrotum
What is Hyperemia
A PHYSIOLOGIC active process of engorgement with bright red, oxygenated blood recruited by signals from affected site. Examples: Inflammation (sun burn) or exercise increasing metabolic activity
What is Congestion (passive hyperemia)
A PATHOLOGICAL process of tissue engorgement with bluish, poorly oxygenated blood. Example: thrombosis, embolism
What is Ischemia
reduction in arterial blood supply (oxygen & nutrients) to a tissue or body part
Causes of Ischemia
Aterial Obstruction; Venous Obstruction; Vasoconstriction; external pressure; heart failure
Effects of Ischemia
Accumulation of metabolic wastes; pain;atrophy; tissue damage (Infarction)
What is an Infarction
necrosis of tissue due to interference in blood supply to that tissue, usually follows ischemia. Usually affects - spleen, kidneys, lung, brain and heart
Sclerosis
it means “hardening”
What is Arteriosclerosis
Thickening, hardening and loss of elasticity of arterial walls partly due to deposition of calcium
What is Atherosclerosis
Hardening of arteries due to build upof waxy plaque inside of blood vessels
Thrombosis
An ATTACHED solid mass or blood clot made up of blood cells. (sickle cell is an example)
Types of Thrombosis
Partial - obstruction of a blood vessel; thrombus can be dislodged Obstruction - Total or complete blockage of a blood vessel, with ischemia & infarction Septic - infected, verydangerous Aseptic - Not infected
Thrombi: Tiny -vs- Large
Tiny Thrombi can resolve on their own. Large Thrombi may grow by becoming surrounded by fibrous tissue. Some Thrombi break off and become emboli
Thrombosis : Resolution
Thrombi dissolve without further damage (small Thrombi)
Thrombosis : Calcification
Mineral salts accumulate around thrombus, may became obstructive
Thrombosis : Fragmentation
pieces of thrombus dislodge and move through the bloodstream
Thrombosis : Septic Softening
septic (infected) thrombus; fragments move through bloodstream –> spread infection & may block small blood vessels
Thrombosis : Canalization
New blood capillaries form around to bypass the thrombus
Thrombosis : Consequences
Ischemia - reduction in arterial blood supply Passive Hyperemia - abnormal venous drainage Gangrene - death of tissue with loss of vascular supply, may be followed by bacterial infection Infarction - tisue necrosis due to obstruction in arterial blood supplying the area Bacteremia - presence of bacteria in blood from a septic thrombus
What is an Embolism
Caused by formation of solid or gaseous object floating free (embolus) in the bloodstream.
Embolism : Consequences
Ischemia; infarction; gangrene; spread of infection; spread of tumor cells; necrosis
Hemorrhage
Loss of blood from the vascular system. Caused by trauma, vascular diseases, blood diseases
Hemorrhage : Petechia
Small tissue damage, visible as purplish hemorrhages of the skin (example: thrombocytopenia - low platelet count)