UNIT 5 Autonomic Nervous System Agents Flashcards
Nervous System
- Central Nervous System
- Peripheral Nervous System
- Central Nervous System
- Peripheral Nervous System
A. Somatic Nervous System
B. Autonomic Nervous System
A. Somatic Nervous System
B. Autonomic Nervous System
- Sympathetic
- Parasympathetic
stimulate sympathetic response
Agonist
block sympathetic response
Antagonist
– fight or flight
SYMPATHETIC NERVOUS SYSTEM
SYMPATHETIC NERVOUS SYSTEM
Effects
- heart rate, bp = increased, GI decreased, mydriasis - dilation
of the pupils
SYMPATHETIC NERVOUS SYSTEM
epinephrine, adrenaline
Neurotransmitters
SYMPATHETIC NERVOUS SYSTEM
alpha and beta receptors
Receptors
SYMPATHETIC NERVOUS SYSTEM
– target – blood vessels
Alpha receptors
SYMPATHETIC NERVOUS SYSTEM
– stimulant
Alpha 1
SYMPATHETIC NERVOUS SYSTEM
– control
Alpha 2
SYMPATHETIC NERVOUS SYSTEM
– target – 1 heart, 2 lungs
Beta receptors
SYMPATHETIC NERVOUS SYSTEM
vasoconstriction - increase heart rate, contraction, mydriasis,
increases blood pressure
Alpha 1 receptor agonist
Examples: phenylephrine, epinephrine
SYMPATHETIC NERVOUS SYSTEM
vasodilation – decrease in bp
Alpha 2 receptor agonist
- Example – Clonidine
SYMPATHETIC NERVOUS SYSTEM
increased heart contractility and heart rate – (Presence of dysrhythmia – hold the ordered dose and inform the doctor) - Increased myocardial contractility
Beta 1 receptor agonist
SYMPATHETIC NERVOUS SYSTEM
– bronchodilation
Beta 2 receptor agonist
Example : Albuterol – the nurse should monitor the patient for palpitations
SYMPATHETIC NERVOUS SYSTEM
blocks both A1 and A2
Non- Selective Alpha Antagonist
Example: Phentolamine
SYMPATHETIC NERVOUS SYSTEM
– blocks only Alpha 1 causing vasodilation,
decrease heart rate, contractility and bp.
Alpha 1 Selective Antagonist
Example: Phentolamine