UNIT 5 Autonomic Nervous System Agents Flashcards

1
Q

Nervous System

A
  1. Central Nervous System
  2. Peripheral Nervous System
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2
Q
  1. Central Nervous System
  2. Peripheral Nervous System
A

A. Somatic Nervous System
B. Autonomic Nervous System

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3
Q

A. Somatic Nervous System
B. Autonomic Nervous System

A
  1. Sympathetic
  2. Parasympathetic
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4
Q

stimulate sympathetic response

A

Agonist

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5
Q

block sympathetic response

A

Antagonist

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6
Q

– fight or flight

A

SYMPATHETIC NERVOUS SYSTEM

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7
Q

SYMPATHETIC NERVOUS SYSTEM

Effects

A
  • heart rate, bp = increased, GI decreased, mydriasis - dilation
    of the pupils
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8
Q

SYMPATHETIC NERVOUS SYSTEM

epinephrine, adrenaline

A

Neurotransmitters

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9
Q

SYMPATHETIC NERVOUS SYSTEM

alpha and beta receptors

A

Receptors

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10
Q

SYMPATHETIC NERVOUS SYSTEM

– target – blood vessels

A

Alpha receptors

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11
Q

SYMPATHETIC NERVOUS SYSTEM

– stimulant

A

Alpha 1

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12
Q

SYMPATHETIC NERVOUS SYSTEM

– control

A

Alpha 2

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13
Q

SYMPATHETIC NERVOUS SYSTEM

– target – 1 heart, 2 lungs

A

Beta receptors

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14
Q

SYMPATHETIC NERVOUS SYSTEM

vasoconstriction - increase heart rate, contraction, mydriasis,
increases blood pressure

A

Alpha 1 receptor agonist

Examples: phenylephrine, epinephrine

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15
Q

SYMPATHETIC NERVOUS SYSTEM

vasodilation – decrease in bp

A

Alpha 2 receptor agonist

  • Example – Clonidine
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16
Q

SYMPATHETIC NERVOUS SYSTEM

increased heart contractility and heart rate – (Presence of dysrhythmia – hold the ordered dose and inform the doctor) - Increased myocardial contractility

A

Beta 1 receptor agonist

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17
Q

SYMPATHETIC NERVOUS SYSTEM

– bronchodilation

A

Beta 2 receptor agonist

Example : Albuterol – the nurse should monitor the patient for palpitations

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18
Q

SYMPATHETIC NERVOUS SYSTEM

blocks both A1 and A2

A

Non- Selective Alpha Antagonist

Example: Phentolamine

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19
Q

SYMPATHETIC NERVOUS SYSTEM

– blocks only Alpha 1 causing vasodilation,
decrease heart rate, contractility and bp.

A

Alpha 1 Selective Antagonist

Example: Phentolamine

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20
Q

SYMPATHETIC NERVOUS SYSTEM

blocks only Alpha 1 causing vasodilation, decrease heart rate, contractility and bp

A

Alpha 1 Selective Antagonist

Example: Prazosin

21
Q

SYMPATHETIC NERVOUS SYSTEM

Beta Blockers

A
  • Non Selective
  • Selective B1 antagonist/blocker
22
Q

SYMPATHETIC NERVOUS SYSTEM

blocks both B1 and B2 causing vasodilation decreasing bp but
bronchoconstriction – don’t give to patient with asthma or respiratory problems.

A

Non Selective

Example : Propranolol

23
Q

SYMPATHETIC NERVOUS SYSTEM

blocks only B1 causing
vasodilation causing a decrease in BP but no bronchoconstriction

A

Selective B1 antagonist/blocker

Example : Metoprolol – less likely to precipitate bronchoconstriction

24
Q

rest and digest

A

PARASYMPATHETIC NERVOUS SYSTEM

25
Q

PARASYMPATHETIC NERVOUS SYSTEM

Effects=

A

heart rate, bp = decreased, GI increased, miosis

26
Q

Cholinesterase inhibitors

A

Parasympathomimetics

27
Q

Acetylcholine

A

Neurotransmitters

28
Q

mimic Acetylcholine

A

cholinergic agonists

29
Q

Receptors

A

Nicotinic and Muscarinic

30
Q

target skeletal muscles

A

Nicotinic receptors

31
Q

target – smooth muscles, salivary glands, gastrointestinal stimulation

A

Muscarinic receptors

32
Q

increase salivation, sweating, urination, gastric acid

A

Muscarinic agonist

Example: Pilocarpine

33
Q

skeletal muscle contraction

A

Nicotinic receptor agonist

34
Q

will cause miosis, diarrhea and bradycardia

A

Bethanechol

35
Q

Nursing management

A

Perform urinary assessment

36
Q

clinical manifestation of extreme muscarinic stimulation

A

Excessive perspiration

37
Q

as a neuromuscular relaxan

A

Succinylcholine

38
Q

cholinesterase inhibitor

A

Physostigmine

39
Q

bradycardia, hypotension, bronchospasm

A

Side effects

40
Q

antimuscarinic agents causing bladder relaxation preventing urinary incontinence.

A

Vasico selective

Example: Oxybutynin – treatment for bladder incontinence – will cause decrease unrination

41
Q

muscarinic antagonists – decrease saliva, mucus secretions, prevent vomiting
Antidote for excessive dosing of bethanechol

A

Atropine

42
Q

increase temp, confusion, flushed face, dryness of mouth, very thirsty

A

Atropine overdose

42
Q

muscle relaxation

A

Neuromuscular blocking drugs

43
Q

nicotinic receptor antagonist

A

Spasmolytics

Example - Dantrolene – skeletal muscle relaxation

44
Q

dilation of pupils

A

Mydriatics

45
Q

antimuscarinic agents causing bladder relaxation preventing urinary incontinence.

A

Vasico selective

Example: Oxybutynin – treatment for bladder incontinence – will cause decrease unrination

46
Q

muscarinic antagonists – decrease saliva, mucus secretions, prevent vomiting
Antidote for excessive dosing of bethanechol

A

Atropine

47
Q

increase temp, confusion, flushed face, dryness of mouth, very thirsty

A

Atropine overdose

48
Q
A