Unit 4. Genetics Flashcards
What macromolecule is DNA?
Nucleic Acid
What is the monomer of DNA?
Nucleotides
What are the three parts of this monomer of DNA?
Deoxyribose sugar, phosphate group, and nitrogen base
What is the difference between a gene and a chromosome?
Chromosomes carry DNA in cells which is responsible for building and maintaining your human structure. Genes are segments of your DNA, which give you physical characteristics that make you unique.
Which nitrogen bases are pyrimidines?
Cytosine, Thymine and Uracil
Which nitrogen bases are purines?
Adenine, and Guanine
Nitrogen bases are held together by what bonds?
Hydrogen bonds
Nucleotides are held together by what bonds?
Phosphate bonds
Because the two strands in DNA run in opposite directions, they are said to be?
Antiparallel structure/Bidirectional
The 5’ end of the DNA strand is indicated by?
Phosphate group
The 3’ end of the DNA strand is indicated by?
Tail end
What are the DNA complementary base pair rules?
Adenine + Thymine & Guanine + Cytosine
What are the RNA complementary base pair rules?
Adenine + Uracil & Guanine + Cytosine
Describe 3 differences between DNA and RNA.
DNA is a double helix, sugar is deoxyribose, and base pairs are Adenine, Thymine, Guanine and Cytosine. RNA is a single strand, its sugar is ribose and its base pairs are Adenine, Uracil, Guanine, and Cytosine.
Describe 2 similarities between DNA and RNA.
Both DNA and RNA are polymers of nucleotides. DNA and RNA both have 3 nitrogen bases: Adenine, Cytosine and Guanine.
Where does DNA Replication take place?
The nucleus
When does DNA Replication take place?
During the S Phase of the cell cycle
What is the result of replication?
2 identical DNA molecules
What is the complementary DNA strand to the one listed below?
A A C T G C A T T T G C
T T G A C G T A A A C G
Explain why DNA Replication is said to be “semi-conservative.”
2 copies are made. One strand is new, while the other is the half of the previous.
List a function of each enzyme in DNA Replication: Helicase, Primase, DNA Polymerase (list two), and Ligase.
Helicase: Unwinds the double helix by breaking hydrogen bonds.
Primase: Builds an RNA primer on leading and lagging strands.
DNA Polymerase: Replication, and also proofreading the duplicated DNA and repairing it.
Ligase: Joins fragments to form a continuous strand
Summarize DNA replication in three steps.
- Unzipping the DNA strand by helicase.
- Primase creates a small complementary sequence of RNA nucleotides.
- Assembly of the new strand.
In DNA replication, the leading strand replicates what and the lagging strand replicates what?
The lagging strand replicates discontinuously forming short fragments, whereas the leading strand replicates continuously
Where can you find DNA in a eukaryotic cell?
The nucleus
What is the Central Dogma?
The flow of information in cells is from DNA to RNA to protein.
List the three types of RNA and their purpose in protein synthesis.
- Messenger RNA (mRNA) molecules carry the coding sequences for protein synthesis and are called transcripts.
- Ribosomal RNA (rRNA) molecules form the core of a cell’s ribosomes (the structures in which protein synthesis takes place).
- Transfer RNA (tRNA) molecules carry amino acids to the ribosomes during protein synthesis.