Unit 4: Cell Cycle & Enzymes Flashcards

1
Q

Cell Division

A

parent cell divided into two daughter cells

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2
Q

Genome

A

complete set of genetic material in an organism

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3
Q

Chromosomes

A

thread-like structures inside the nucleus of plant and animal cells

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4
Q

Chromatin

A

mixture of DNA and proteins that form the chromosomes found in the cells of humans and other higher organisms

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5
Q

Somatic Cells

A

cells in the body other than sperm and egg cells

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6
Q

Sister Chromatids

A

the identical copies formed by the DNA replication of a chromosome, with both copies, joined together by a common centromere

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6
Q

Gametes

A

organisms reproductive cells

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7
Q

Centromere

A

constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (Mitosis and Meiosis)

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8
Q

Mitosis

A

type of cell division in which the mother cell divides to produce two daughter cells that are genetically identical to itself

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9
Q

Cytokinesis

A

physical process of cell division, which divides the cytoplasm of a parental cell into two daughter cells

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10
Q

M Phase

A

one parent cell physically divides into two daughter cells

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11
Q

Interphase

A

the phase of a cell cycle in which a typical cell spends most of its life, the “metabolic phase”, the cell obtains nutrients and metabolizes them, grows, and replicates its DNA in preparation for mitosis

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12
Q

G 1

A

the first of four phases of the cell cycle that takes place in eukaryotic cell division, the cell synthesizes mRNA and proteins in preparation for subsequent steps leading to mitosis

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13
Q

G 2 & S Phases

A

in the S phase cell copies its DNA to produce two sister chromatids and replicates its nucleosomes, G2 phase involves further cell growth and organisation of cellular contents

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14
Q

Prophase

A

the first phase of mitosis, a process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells

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15
Q

Prometaphase

A

second phase of mitosis, process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells

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16
Q

Metaphase

A

stage during the process of cell division (Mitosis & Meiosis), nucleus dissolves and the cell’s chromosomes condense and move together, aligning in the center of the dividing cell

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17
Q

Anaphase

A

the fourth phase of mitosis, a process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells

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18
Q

Telophase

A

fifth and final phase of mitosis, a process that separates the duplicated genetic material carried in the nucleus of a parent cell into two daughter cells

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19
Q

Mitotic Spindle

A

macromolecular machine that segregates chromosomes to two daughter cells during mitosis

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20
Q

G 0 Phase

A

period of the cell cycle during which the cell is neither dividing nor preparing to divide

20
Q

Kinetochore

A

arge proteinaceous structure that mediates interactions between chromosomal DNA and spindle-microtubule polymers

21
Q

Metaphase Plate

A

imaginary line that runs across the cell, dividing the cell into hemispheres

22
Q

Cleavage

A

series of miotic divisions where the enormous volume of egg cytoplasm is divided into numerous smaller, nucleated cells

23
Cleavage Furrow
area of cell surface invagination that occurs during the process of cytokinesis
24
Cell Plate
structure that forms when the cytoplasm of a plant divides
25
Binary Fission
process of one cell simply dividing into two
26
Checkpoint
stage in the eukaryotic cell cycle at which the cell examines cues and "decides" whether or not to move forward with division
27
Cell Cycle Control System
triggers the major processes of the cell cycle
28
Cyclin
group of proteins that control the progression of the cell cycle by activating particular enzymes
29
MPF
Maturation-promoting factor, protein kinase made from two subunits
29
Cyclin-Dependent Kinases
protein kinases characterized by needing a separate subunit that provides domains essential for enzymatic activity
30
Growth Factor
a secreted biologically active molecule that can affect the growth of cells
31
Density-Dependent Inhibition
happens when cells grow to a limited density then growth becomes inhibited, possibly by cell-cell contacts
32
Anchorage Dependence
ability of normal cells to grow by attaching themselves to a rigid surface
33
Transformation
specific process where exogenous genetic material is directly taken up and incorporated by a cell through its cell membrane
34
Benign Tumor
abnormal but not cancerous collection of cells
35
Malignant Tumor
cancerous cells
36
Catalyst
substance that speeds up chemical reactions, or lowers the temperature or pressure needed to start one, without itself being consumed during the reaction
37
Enzyme
biological catalyst and is almost always a protein
38
Activation Energy
minimum energy required for a reaction to occur
39
Substrate
the surface on which an organism lives or the substance on which an enzyme can act
40
Product
end substances after a biological process has occured
41
Enzyme-Substrate Complex
temporary molecule formed when the substrate binds to the enzyme
42
Active Site
the part of an enzyme to which substrates bind and where a reaction is catalyzed
43
Induced Fit
the substrate binds to an active site and both change shape slightly, creating an ideal fit for the catalyst
44
Cofactors
a non-protein chemical compound or metallic ion that is required for an enzymes role as a catalyst
45
Coenzymes
organic molecule that binds to the active sites of certain enzymes to assist in the catalysis of a reaction
46
Competitive Inhibitors
competes with substrate for binding to an active site
47
Noncompetitive Inhibitors
inhibitor binds at an allosteric site separate from the active site of substrate binding
48
Allosteric Regulation
any form of regulation where the regulatory molecule binds to an enzyme someplace other than the active site
49
Feedback Inhibition
cellular control mechanism, in which the activity of an enzyme is inhibited by the end product of a biochemical pathway