Unit 3 Test (From Winter 2013) Flashcards
What is the hyperpolarized membrane potential?
-90 mV
What is the membrane potential which triggers voltage-gated potassium channels to open?
+30mV
What is the membrane potential maintained by the sodium-potassium pump?
-70mV
What is the sub-threshold membrane potential?
-55 tp -50 mV
What is the membrane potential which triggers voltage-gated sodium channels to close?
+30
What is the membrane potential caused by an IPSP?
-90mV
What is an IPSP?
an “inhibitory postsynaptic potential” which is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential
Does a strong stimuli cause the ampitude of a generated action potential to increase?
no, false
What happens to the action potential when there is a strong stimulis?
It fires more often; therefore stimulus strength is translated as action potential frequency.
Astrocytes function:
- most abundant, versalite, & highly branced gial cells
- cling to neurons and their synaptic endings, covering up capillaries
- support & brace neurons
- anchor neurons to their capillary nutrients
- guide migration of young neurons
- help control ion & neurotransmitter enviroment
Ependymal Cells:
- ciliated cells that range in shape from cuboidal/columnar
- line central cavities of brain & spinal column
- ciliated cells funtion to move CSF
Schwann Cells
- glial cells that wrap around a nerve fiber in the peripheal nervous system
- forms the myelin sheaths of peripheral axons (form from fatty tissue)
Oligodendrocytes
- branched cells wrap around CNS nerve fibers
- forms insulating covers aka myelin sheaths
acetylcholine
It is the excitatory neurotransmitter that is secreted by motor neurons innervating skeletal muscle
-excitatory neurotransmitter
dopamine
- a chemical released by nerve cells to send signals to other nerve cells
- involved in motor control and in controlling the release of several important hormones
- inhibitory neurotransmitter
- affects attention, learning, movement & pleasure
norepinephrine
- hormone and neurotransmitter most responsible for concentration - alertness
- role as the neurotransmitter released from the sympathetic neurons to affect the heart
- excitatory neurotransmitter
gamma aminobutyric acid (GABA)
- is a chemical neurotransmitter
- -inhibitory neurotransmitter
- contributes to motor control, vision, and many other cortical functions
Graded potentials:
- they may sum temporarally or spatially
- Stimulation of a neuron causes sodium gates to open and the membrane becomes partially depolarized as sodium ions enter the neuron
- called “graded” because the amount of depolarization depends on the strength of the stimulus
What is the absolute refractory period?
the period after an inital stimulus when the neuron is not sensitive to another stimulus
What is the refractory period?
-the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its resting state following an excitation
What is a threshold in an action potential?
The minimum stimulus needed to achieve an action potential
nuclei
cluster of nerve cell bodies in CNS
nerves
Any of the cordlike bundles of fibers made up of neurons through which sensory stimuli and motor impulses pass between the brain or other parts of the central nervous system and the eyes, glands, muscles, and other parts of the body. Nerves form a network of pathways for conducting information throughout the body
ganglia
cluster of nerve cell bodies in PNS
tracks
they are myelinated axons that are located within the central nervous system
efferent Neuron
Sends message away from CNS
Afferant neuron
sends message towards CNS
interneuron
connects messages within CNS pathway (inside of spintal cord)
Glial Cell
- supporting cells
- provide supportive framework for neurons
- segregate & insulate neurons
- guide young neuros to proper connections
- promote health & growth of neurons
What is the roll of acetylcholinesterase?
breaks down acetylcholine soon after its released into the synaptic cleft
What is saltatory conduction?
- When a current passes through a myelinated axon only at the nodes of Ranvier
- AP triggered only at nodes and “jump” from one node to the next
- much faster than unmyelinated axons
What are the neuroglia (gial cells) in the CNS?
astrocytes, microglia, ependymal cells and oligodendrocytes
What are the neuroglia (gial cells) in the PNS?
Satellite cells, schwann cells
What is a chemical synapses?
specialized for release and reception of chemical neurotransmitters (2 parts, axon terminal & receptor region)
Group A Fibers
- have greatest amount of myelination & fastest (300mph)
- cary sensory signals from skin and joints
- carry motor signals to skeletally muscles
Group B Fibers
- lightly myelinated (30 mph)
- carry sensory & motor signals for internal (visceral) organs and some skin
Group C Fibers
- unmyelinated (2mph)
- not wrapped by but can be supported by Schwann cells
- cary sensory & motor signals for internal organs only
Synaptic Cleft
- it is the chemical synapses that convers electric signals into chemical signals (via neurotransmitters)
- it is the fluid filled space separating the presynaptic & postsynaptic neurons
What is there to know about a information transfer for a synaptic cleft? (6 steps)
1) action potential arrives at axon terminal
2) voltage gated CA 2+ channels open & CA2+ enters axon terminal
3) when CA2+ enters it causes neurotransmitter-containing vesicles to release their contents by exocytosis
4) neurotransmitters diffuses across synaptic cleft & binds to specific receptors on postsynaptic membrane
5) binding of neurotransmitter opens ion channels resulting in graded potentials
6) neurotransmitters effects are terminated
what does the termination of a neurotransmitter effect?
- blocks reception of additional messages
- must be removed from receptor to stop effect (enzymatic degradation, reabsorption by astrocytes or presynaptic terminals, by diffusion)
EPSP
excitatory postsynaptic potentials:
-local depolarization of postsynaptic membrane that brings neuron closer to AP threshold
What is a neurotransmitter?
-chemical signal used for neuronal communication with the body & brain
What are the two types of myelinated cells in the PNS & CNS?
Schwann cell (PNS) Oligodendrocytes (CNS)
Where is the fourth ventriccle located (in the brain)?
under the cerebreal aquaduct which connects it to the 3rd ventricle