Unit 3 Test Flashcards
enzymes
A macromolecule serving as a catalyst, a chemical agent that increases the rate of a reaction without being consumed by the reaction. Most enzymes are proteins.
catalyst
A chemical agent that selectively increases the rate of a reaction without being consumed by the reaction.
activation energy
The amount of energy that reactants must absorb before a chemical reaction will start; also called free energy of activation.
substrate
The reactant on which an enzyme works.
active site
The specific region of an enzyme that binds the substrate and that forms the pocket in which catalysis occurs.
induced fit
Caused by entry of the substrate, the change in shape of the active site of an enzyme so that it binds more snugly to the substrate.
cofactors
Any nonprotein molecule or ion that is required for the proper functioning of an enzyme. Cofactors can be permanently bound to the active site or may bind loosely and reversibly, along with the substrate, during catalysis.
coenzyme
An organic molecule serving as a cofactor. Most vitamins function as coenzymes in metabolic reactions.
competitive inhibitor
A substance that reduces the activity of an enzyme by entering the active site in place of the substrate, whose structure it mimics.
noncompetitive inhibitor
A substance that reduces the activity of an enzyme by binding to a location remote from the active site, changing the enzyme’s shape so that the active site no longer effectively catalyzes the conversion of substrate to product.
allosteric regulation
The binding of a regulatory molecule to a protein at one site that affects the function of the protein at a different site.
cooperativity
A kind of allosteric regulation whereby a shape change in one subunit of a protein caused by substrate binding is transmitted to all the other subunits, facilitating binding of additional substrate molecules to those subunits.
feedback inhibition
A method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway.
metabolic pathways
A series of chemical reactions that either builds a complex molecule (anabolic pathway) or breaks down a complex molecule to simpler molecules (catabolic pathway).
cellular respiration
The catabolic pathways of aerobic and anaerobic respiration, which break down organic molecules and use an electron transport chain for the production of ATP.
aerobic respiration
A catabolic pathway for organic molecules, using oxygen (O2) as the final electron acceptor in an electron transport chain and ultimately producing ATP. This is the most efficient catabolic pathway and is carried out in most eukaryotic cells and many prokaryotic organisms.
fermentation (anaerobic)
A catabolic pathway in which inorganic molecules other than oxygen accept electrons at the “downhill” end of electron transport chains. // A catabolic process that makes a limited amount of ATP from glucose (or other organic molecules) without an electron transport chain and that produces a characteristic end product, such as ethyl alcohol or lactic acid.
redox reactions
A chemical reaction involving the complete or partial transfer of one or more electrons from one reactant to another; short for reduction-oxidation reaction.
oxidation
The complete or partial loss of electrons from a substance involved in a redox reaction.
reduction
The complete or partial addition of electrons to a substance involved in a redox reaction.
NAD+/NADH
The oxidized form of nicotinamide adenine dinucleotide, a coenzyme that can accept electrons, becoming NADH. NADH temporarily stores electrons during cellular respiration. // The reduced form of nicotinamide adenine dinucleotide that temporarily stores electrons during cellular respiration. NADH acts as an electron donor to the electron transport chain.
FADH/FADH2
a redox cofactor that is created during the Krebs cycle and utilized during the last part of respiration, the electron transport chain
oxidative phosphorylation
The production of ATP using energy derived from the redox reactions of an electron transport chain; the third major stage of cellular respiration.
substrate-level phosphorylation
The enzyme-catalyzed formation of ATP by direct transfer of a phosphate group to ADP from an intermediate substrate in catabolism.
glycolysis
A series of reactions that ultimately splits glucose into pyruvate. Glycolysis occurs in almost all living cells, serving as the starting point for fermentation or cellular respiration.