Unit 3: Practice Questions Flashcards

1
Q

Between Tryptophan (charged) and indole (uncharged) which is more soluble?

A

Indole is more soluble because not ion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The porin proteins utilize the _____ structural motif

a) alpha helix
b) beta sheet

A

b) beta sheet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What role do van der Waals interactions play in membranes?

a) favor the self assembly of the lipid bilayer
b) decrease the melting temperature
c) increase membrane fluidity
d) decrease the membrane fluidity

A

d) decrease membrane fluidity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Association of proteins with membranes that do NOT exist are:

a) integral membrane spanning beta sheet with nonpolar side groups outside
b) integral membrane spanning alpha helices with polar side groups outside
c) integral membrane spanning nonpolar alpha helices
d) peripheral polar interactions with phospholipid heads

A

If Lipid A has a higher Tm than lipid B, which of the following differences between A and B may exist?

a) A has short fatty acid chains than B
b) A has longer fatty acid chains than B
c) A has more unsaturated fatty acid chains than B
d) A has more saturated fatty acid chains than B
e) A has trans unsaturatd fatty acid chains wheras B has cis saturated fatty acid chains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Secondary transporters (or cotransporters) can be divided into symporters and antiporters. What is the basis for this distinction?

a. Symporters allow the same molecule to be moved in both directions, while antiporters allow it to move in only one direction.
b. Symporters use the energy from one molecule moving down its concentration gradient to drive the movement of a second molecule in the opposite direction against its concentration gradient, while antiporters drive the movement in the same direction.
c. Symporters use the energy from one molecule moving down its concentration gradient to drive the movement of a second molecule, wheras antiporters use the energy from both molecules for transport
d. Symporters use the energy from one molecule moving down its concentration gradient to drive the movement of a second molecule in the same direction against its concentration gradient, while antiporters drive the movement in the opposite direction.

A

d. Symporters use the energy from one molecule moving down its concentration gradient to drive the movement of a second molecule in the same direction against its concentration gradient, while antiporters drive the movement in the opposite direction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The Na+ - K+ pumps in active transport that

a) pumps Na+ into the cell and K+ out of the cell
b) pumps Na+ out of the cell and K+ into the cell
c) provides energy such as Na+ and K+ can move freely in either direction
d) pumps both Na+ and K+ into the cell

A

b) pumps Na+ out of the cell and K+ into the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the following would be expected to lower the Tm for a phospholipid bilayer?

a) replacing a lipid containing carbon 18 fatty acids with one containing carbon 16 fatty acids
b) adding ions that bind to charged groups in the polar head groups
c) replacing a lipid containing unsaturated fatty acids with one containing saturated fatty acids
d) decreasing the concentration of phospholipids

A

a) replacing a lipid containing carbon 18 fatty acids with one containing carbon 16 fatty acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The common way in which integral membrnae proteins span the membrane is in

a) alpha helical segments
b) single strands with no secondary structure
c) paired alpha helical and beta sheet segments
d) beta sheet structures

A

a) alpha helical segments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Select the fundamental properties of all ion channels

  1. rapid transport
  2. selectivity
  3. use active transport
  4. voltage gated
A

1 and 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a receptor protein?

a) a protein that spans the plasma membrane
b) a plasma membrane protein that binds with first messengers
c) a vesicle that transports large particles across the plasma membrane
d) an intracellular chemical that activates intracellular enzymes
e) an extracellular ligand that signals intracellular activity to change

A

b) a plasma membrane protein that binds with first messengers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Select the structural features common to all membrane bound receptors

  1. seven membrane bund receptors
  2. intracellular domain undergoes structural changes upon extracellular ligand binding
  3. signal molecule binding site on extracellular domain
  4. kinase domain
A

2 and 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What factor does not contribute to the high phosphoryl transfer potential of ATP?

a) adenine ring structure
b) charge repulsion
b) ability of water to interact more favorably with products of ATP hydrolysis than with ATP itself
d) resonance stabilization

A

a) adenine ring structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What statement correctly describes metabolic reactions?

a) Anabolic processes break down material and transform fuels in cellular energy, wheras catabolic processes require energy for biosynthesis
b) Metabolism breaks down material and transforms fuels in cellular energy, wheras intermediary metabolism requires energy for biosynthesis
c) Catabolic processes break down material and transforms fuels in celular energy, wheras anabolic processes require energy for biosynthesis

A

c) Catabolic processes break down material and transforms fuels in celular energy, wheras anabolic processes require energy for biosynthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What needs to be invested for glucogenesis

A

Invest 4 ATP, 2 GTP, 2 NADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Dr. Kim has discovered a molecule she believes to be a signaling molecule associated with signal transduction. This molecule is hydrophilic; therefore, you expect it to interact with a receptor ____.

a) in the nucleus of the cell
b) within the cytoplasm of the cell
c) on the cell surface
d) on the cytoplasmic surface of the plasma membrane

A

c) on the cell surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

If the reaction A –> B has DeltaG of +25 J/mol and the reaction B –> C has deltaG of -15 J/mol, the overall energy change A –> C will be:

a) - 40 Joule/mol.
b) - 15 Joule/mol.
c) +10 Joule/mol.
d) +40 Joule/mol.

A

c) +10 Joule/mol.

17
Q

At a given time, a cell contains 10mM ATP, 1mM ADP, 10mM AMP, and 10mM Pi. What is the phosphorylation potential of the cell?

a) 0.1
b) 0.5
c) 0.9
d) 1.0
e) 1.1

A
18
Q

The conversion of one molecule of fructose 1,6 -bisphosphate into two molecules of pyruvate results in the net synthesis of:

a) two molecules of NADH and two molecules of ATP
b) two molecules of NAD+ and three molecules of ATP
c) two molecules of NADH and four molecules of ATP

A

c) two molecules of NADH and four molecules of ATP

19
Q

The major tissues carrying out gluconeogenesis are the ____ and ____.

a) brain; muscles
b) muscles; kidneys
c) liver; red blood cells
d) red blood cells; brain
e) liver; kidneys

A

e) liver; kidneys

20
Q
A