Chapter 24

Question 1

2 key biochemical componets required for growth

Answer 1

1. ribose sugars
2. biochemical reducing power: NADPH

Question 2

Pentose phosphate pathway yields

Answer 2

NADPH and 5 carbon sugars

Question 3

Pentose phosphate pathway and glycolysis showcase

Answer 3

coordinated control

Question 4

NADPH

Answer 4

biosynthetic reducing power of NADPH key product of Pentose Phosphate pathway

Question 5

First phase of pentose phosphate pathway

Answer 5

oxidative generation of NADPH and produced 5 carbon sugars

Question 6

Second phase of pentose phosphate pathway

Answer 6

Nonoxidative interconversion of variety of sugars

Question 7

Location of pentose phosphate pathway

Answer 7

Cytoplasm

Question 8

PAthways requiring NADPH include

Answer 8

synthesis (biosynthesis)
detoxification (reduction and catabolism)

Question 9

glucose 6 phosphate is found in what pathways

Answer 9

glycolysis
gluconeogenesis
glcogen metabolism
pentose phosphate pathways

Question 10

Reaction 1 of Pentose phosphate pathway

Answer 10

Oxidation
Glucose 6 phosphate oxidized to 6 phosphogluconate
Catalyzed by glucose 6 phosphate dehydrogenase
Produces NADPH

Question 11

Key regulatory enzyme of pentose phosphate pathway

Answer 11

Glucose 6 phosphate dehydrogenase

Question 12

Reaction 2 of Pentose phosphate pathway

Answer 12

Oxidative carboxylation
6 phosphogluconate decarboxylated to ribulose 5 phosphate (5 carbon ketose)
Catalyzed by phosphogluconate dehydrogenase
Produces NADPH, 5 carbon ketose, CO2

Question 13

Reaction 3 of pentose phosphate pathway

Answer 13

ribulose 5 phosphate isomerized to ribose 5 phosphate
Catalyzed by phosphopentose isomerase
Ketose to aldose

Question 14

What is the most important reaction for nucleotide metabolism?

Answer 14

Reaction 3
Ribulose 5 phosphate to ribose 5 phosphate by phosphopentose isomerase
Ribose 5 phosphate used to convert into variety of sugars

Question 15

Reaction 4 of pentose phosphate pathway

Answer 15

Ribulose 5 phosphate to xylulose 5 phosphate
3rd carbon switch –> epimers
Catalyzed by phosphopentose epimerase

Question 16

Xylulose 5 phosphate

Answer 16

5 carbon
alternate pentose source

Question 17

After formation of ribose 5 phosphate or xylulose 5 phosphate is used for

Answer 17

Carbon rearrangement occurs

Question 18

Transketolase

Answer 18

transfers 2 carbon unit

Question 19

Transoaldolase

Answer 19

transfers 3 carbon unit

Question 20

Why is carbon reaarangment important

Answer 20

Allows for variety of sugars and intermediates seen in glycolysis and gluconeogenesis

Question 21

5 Carbon + 5 Carbon –> 3 Carbon + 7 Carbon is example of :

Answer 21

Transketolase

Question 22

4 Carbon + 5 carbon –> 6 carbon + 3 carbon is example of

Answer 22

Transketolase

Question 23

3 Carbon + 7 carbon –> 6 carbon + 4 carbon is example of:

Answer 23

Transaldolase