Unit 3: Genetics & Evolutionary Foundations Of Behaviour (Chapter 3) Flashcards
Nature
The result of our genetic makeup.
Nurture
The environment and experiences that shape us.
Genome
Complete set of genetic material; the “blueprint” for making & maintaining an organism.
DNA
Molecule that carries genetic information, organized and packaged within chromosomes.
- Most human body cells carry 2 pairs of 23 chromosomes (46 total).
- Exception: reproductive cells, which carry 23.
Gene
Segment of DNA that codes for a particular protein. Humans have 2 versions (alleles) of each gene, 1 from each parent.
Genotype
Made up of 2 alleles for a particular gene. An individual may be homozygous for gene (NN or nn) or heterozygous for gene (Nn).
Phenotype
Observable characteristics of an individual, produced by interaction of genotype and environment.
Recessive alleles
Determine phenotype only when individual is homozygous for gene.
Not all genes act in dominant/recessive fashion
Dominant alleles
Determines phenotype regardless of whether an individual is homozygous or heterozygous for gene.
Not all genes act in dominant/recessive fashion
What do genes code for?
Genes code for proteins, which contribute to phsycial structures & fuctons of the body, including the brain. Multiple genes are involved in giving rise to complex mental states, behaviours, and traits.
Ex: Code proteins and enzymes involved in production of chemical “messengers” and their receptors that allow neurons to “talk” to each other.
Behavioural genetics
Establishing the degree of heritability for a trait. (I.e. How much variability for a trait can be attributed to genes.)
Evolutionary psychology
Examining why certain genetically-encoded behaviours & traits emerged.
Candidate gene studies
Compare individuals with the candidate gene with individuals without on a given trait or disorder.
Limitations of candidate gene studies
- Typically correlational in nature (other factors, like other genes, cannot be ruled out).
- Underestimate biological complexity of multifaceted traits & behaviours.
- Many promising candidate gene studies have failed to replicate.
Gene knockout
Remove or deactivate gene; modify it so it no longer produces its typical proteins.
Gene knockdown
Make gene less active; “turn down” its volume.
Ex: Mice who don’t miss mom study; genetic knockdown of the u-opioid receptor = defecits in attatchment.
Genome-wide association studies (GWAS)
Instead of looking at single gene (or small set of genes), scan entire genome & look for associations with particular phenotype. This may allow us to identify variants missed through candidate gene approaches.
GWAS Limitations
- Run the rish of false positives,
- Biological relevance often not clear.
- Correlational.
How do genes shape our environments?
Genes shape behavioural tendencies & preferences, and thus environments individuals seek out.
Ex: Individuals genetically predisposed to anxiety may seek less stressful professions.
Environments moderate the impact of genes
The effect of a gene on the manifestation of a particular phenotype may depend on context. In statistical terms, context moderates impact of gene (can also say that genes and environments interact to produce outcomes). Not all genes read all the time, and environment affects which ones are turned “on” and “off”. Our genome is a blueprint for many potential biological selves.
Ex: Twin studies; chronic social isolation study (both regarding expression of genes).
Diathesis-Stress Model
Some individuals have a predisposition (diathesis) that makes them more vulnerable to negative environmental influences (e.g., stress).