Unit 3. Cell Membrane Flashcards
T or F
All cells have a cell
membrane.
T
2 functions of cell membrane
a. Controls what enters
and exits the cell to
maintain an internal
balance called
homeostasis.
b. Provides protection and
support for the cell
Cell membrane contains almost
proteins called
Membrane proteins
It is a double layer of
phospholipids
lipid bilayer
T or F
Cell membranes have pores (holes) in it.
T
Lipid Bilayer contains: (3)
a. Phosphate head is polar
• (water loving)
b. Fatty acid tails are non-polar
• (water fearing)
c. Proteins embedded in
membrane
The property of cell membrane to allow some molecules in
and keeps other molecules out.
Selective permeability
In 1972, they proposed that the
membrane is a mosaic of proteins dispersed within the
bilayer, with only the hydrophilic regions exposed to
water. (Who at what model is it?)
Seymour Jonathan Singer and Garth L. Nicolson
Fluid Mosaic Model
T or F
A molecule always flip-flop
transversely across the membrane
F
always —> rarely
T or F
Variations in lipid composition of cell membranes of many species appear to be adaptations to specific environmental conditions
T
- proteins that penetrate the hydrophobic core
- 70% of Cell membrane proteins part
and parcel of membrane structure
Integral proteins
proteins that are bound to the surface of
the membrane
Peripheral proteins
They transfer substances against Concentration/Electrical gradients
Pumps
Opened and closed by gates
Channel proteins
Involved in transport of substances
Carrier Proteins
Takes place in membrane reaction
Enzyme proteins
They bear appropriate sites for
recognition of Specific Ligands.
Receptor proteins
Which statement/s is/are true about the role of membrane carbohydrates
in cell-cell recognition?
A. Cells recognize each other by binding to surface
molecules, often containing carbohydrates, on
the extracellular surface of the plasma
membrane.
B. Membrane carbohydrates may be covalently
bonded to lipids (forming glycolipids) or more
commonly to proteins (forming glycoproteins)
C. Both statements are true.
D. None
C
Receptor and co-receptor where HIV binds.
CD4
CCR5
T or F
HIV cannot infect a cell lacking CCR5 on its surface
T
Which statement/s is/are true?
A. Hydrophobic (nonpolar) molecules, such
as hydrocarbons, cannot be dissolved in the lipid bilayer, thus, cannot pass through the membrane
• Polar molecules, such as sugars, can cross the membrane easily
C. Both statements are true.
D. None
D
- non polar can dissolve and pass through rapidly
- polar molecules cannot cross easily
allow passage of hydrophilic substances across the membrane
Transport proteins