Unit 2.3 Flashcards
Essential amino acids
Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Threonine
Tryptophan
Valine
Nonessential amino acids
Alanine
Arginine
Asparagine
Aspartic acid
Cysteine
Glutamic acid
Glutamine
Glycine
Proline
Serine
Tyrosine
High quality/complete protein contains:
Ample amount of all essential amino acids
What counts as high quality/complete protein
Animal protein (except gelatin)
Low quality (incomplete) protein
Deficient or low in one or more EAA
Plant protein (except quinoa, buckwheat and soy)
Limiting amino acid means—
Protein cannot be assembled (all or none principle
Source of minerals in animal protein
Fe, Zn, Se
Source of some vitamins in animal protein
Thiamine
Niacin
Riboflavin
B-6
B-12
What is animal protein high in?
Cholesterol and saturated fatty acids
There is no ___ and ____ in animal protein
Fiber
Phytochemicals
Some minerals found in plant protein
Mg, Mn
Some vitamins in plant protein
A
C
E
K
Folate
Plant protein has no ____ and is low in _____
it is a good source of:
No cholesterol
Low SFA
Good source of fiber and phytochemicals
Legumes are rich sources of?
Protein
1/2 cup of protein meets ____% of protein needs but __% of energy needs
10%
5%
Legumes are a ____ protein.
Lean
Legumes are a rich source of ____ and _____
They have no ____ or ___
Fiber and phytochemicals
No cholesterol or SFA
What essential amino acids are deficient in plant proteins?
Lysine
Methionine
Tryptophan
Limiting amino acid in…
Grains:
Veggies:
Nuts:
Legumes:
Lysine
Methionine
Lysine
Methionine
Dietary protein digestion stimulates the release of _____ and _____ from SI
CCK (cholecystokinin)
Secretin
CCK stimulates _____ to release_____
Pancreas
Zymogens
Secretin stimulates _____ to release ____.
Pancreas
HCO3-
What inhibits gastric motility?
Gastric inhibitory polypeptide (GIP)
Activation of trypsinogen to trypsin is done by:
Enteropeptidase and trypsin
Activation of zymogens is done by:
Trypsin
Enzymes break peptides mostly into:
Amino acids
Absorbed amino acids are transported to the _____ via:
Liver
Portal vein
Activation, source and specificity of…
Pepsinogen
Activation: H+ and pepsin
Source: chief cells of stomach
Specificity: Mostly phenylalanine
Activation, source and specificity of…
Trypsinogen
Activation: Enteropeptidase and trypsin
Source: Pancreas
Specificity: Lysine and arginine
Activation, source and specificity of…
Chymotrypsinogen
Activation: trypsin and chyomtripsin
Source: pancreas
Specificity: aromatic and bulky amino acids
Activation, source and specificity of…
Proelastase
Activation: trypsin
Source: pancrea
Specificity: small AA Ala/Gly/Ser
Activation, source and specificity of…
Procarboxypeptidase A/B
Activation: trypsin
Source: pancreas
Specificity: carboxy-end of peptide
Activation, source and specificity of…
Aminopeptidases
Activation: none
Source: small intestine
Specificity: amino end of peptide
Activation, source and specificity of…
Enteropeptidase
Activation: none
Source: small intestine
Specificity: trypsin
Review slide 18
Slide 18
Amino acid, AKA
Transamination
What aminos undergo transamination
All AA except Lys and Leu
Aminos are transferred by:
With the coenzyme:
Aminotransferases
PLP (vitamin B-6)
Where are aminos transferred
Cytosol and mitochondria
What undergoes oxidative deamination
Only Glu
Oxidative deamination is done by:
With the coenzyme:
Glutamate dehydrogenase (liver)
NAD+/NADP+ (niacin)
Oxidative deamination is done where?
Cytosol and mitochondria
Proteins are the building blocks of what body compartments ?
Cell major component after water
Muscle
Enzymes
Hormones
Antibodies
Visual pigments
Functions of proteins
Building blocks of body components
Maintain fluid balance
Contribute to acid/base balance
Supports immune system
Forms glucose
Provides energy
Vitamin source
Contribute to satiety
Standard blood protein level
What happens if low?
3.5-5.5 g/100 ml
If below, swelling of tissues occurs (edema)
What does protein effect in managing acid/base balance
Serum albumin
Hemoglobin
What happens if there is low protein for the immune system
Very weak immune system (anergy) and common diseases can be fatal
Which AA are glucogenic?
Most are
Only lysine and leucine are not
Proteins need a lot of process by ___ and _____.
Liver
Kidneys
Niacin can be synthesized from:
Tryptophan
Compared to other macronutrients, proteins provide the highest feeling of ____ after a meal
Satiety
Blood proteins are important for:
Maintaining the body’s fluid balance
Without sufficient protein in the blood, ____ develops
Edema
What are some situations when positive nitrogen balance occurs?
Growth
Pregnancy
Recovery stage after illness/injury
Athletic training resulting in increased lean body mass
Increased secretion of certain hormones, such as insulin, growth hormone, and testosterone
What are situations when nitrogen equilibrium occurs?
Healthy adult meeting protein and energy needs
What are situations when negative nitrogen balance occurs?
Inadequate intake of protein
Inadequate energy intake
Conditions such as fevers, burns and infections
Bed rest for several days
Deficiency of essential amino acids (ex- poor quality protein consumed)
Increased protein loss (as in some forms of disease)
Increased secretion of certain hormones, such as thyroid hormone and cortisol
What is the RDA for protein?
0.8 g per kg of HBW
70kg X 0.8 g/kg = 56 g of protein
RDA for protein during pregnancy
~10-15 g/day
Endurance athletes may need _____ g per kg of healthy weight of protein
0.8-1.7
RDA percentage
How much does the typical American take in?
8-10%
About 15%
Can excess protein be stored as protein?
No
FNB advises against protein intakes greater that ___% of total calories and energy intake
35%
T/F
Excess protein provides additional health
False
Why does intake of animal protein increase risk for heart disease
High in SFA, cholesterol and calories
Excessive intake of red meat is linked with:
Colon cancer and extra burden on kidneys (stones)
High protein diets increase ____ loss
Calcium
AA supplements may cause _____ and _____
Especially:
How?
Imbalances and toxicity
W/ methionine, cysteine and histidine
Supplement can overwhelm the absorptive mechanism since the body is designed to handle whole proteins
Examples of protein energy malnutrition
Kwashiorkor
Maramus
What is kwashiorkor
Severe protein (w moderate energy) deficit; often accompanied by infections or other diseases
Characteristics of kwashiorkor
Edema
Mild-moderate weight loss
Maintenance of some muscle and subcutaneous fat
Growth impairment (60-80% of normal Wright for age)
Rapid onset
Fatty liver
What is marasmus?
Severe energy and protein deficit
Characteristics of marasmus
Severe weight loss
Wasting of muscle and body fat (skin and bones appearance)
Severe growth impairment (less than 60% of normal Weight for age)
Develops gradually
Types of vegetarian lifestyles
Vegan (plant food only)
Fruititarian (primarily fruits, nuts, honey and vegetable oils)
Lactovegetarian (plant and dairy products)
Lactoovovegeterian (plant products, dairy products and eggs)
Key nutrients in grains
Protein
Thiamine
Niacin
Folate
Vitamin E
Zinc
Magnesium
Iron
Fiber
Key nutrients in legumes
Protein
Vitamin B-6
Zinc
Magnesium
Fiber
Key nutrients in nuts and seeds
Protein
Vitamin E
Magnesium
Key nutrients in veggies
Vitamin A
Vitamin C
Folate
Vitamin K
Potassium
Riboflavin is found in..
Milk products and green leafy veggies
Vitamin D is found in..
Enriched milk and soy/plant milk and sun exposure
Vitamin B12 is found in..
Meats, vitamin B-12-fortified foods
Iron is found in…
Meats, bread group, whole-grains, dried fruits and nuts
Zinc is found in…
Meat, whole-grains, cereals, nuts and legumes
Calcium is found in..
Milk products
Ca-fortified foods
Dark-green leafy veggies
Who is highest at risk for deficiency?
Vegetarian infants and children
For vegetarian infants/children, you must ensure adequate intake of..
Iron, vitamin B12, vitamin D and calcium
_______ diet may prevent infants or children from meeting energy needs
High-fiber
How can you help vegetarian infants and children meet energy needs?
Replace whole-grain products with refined grain products, fruits juices and peeled fruits
Include fortified soy milk, nuts, dried fruits and avocados as alternative sources of calories