Unit 2 Questions and Flashcards - Pharm FlashCards
1
Q
A known side effect of veteranitib
A
QT elongation
2
Q
temozolomide is a prodrug T/F
A
false (temozolomide is an alkyating agent)
3
Q
what’s a mechanicsm of resistance for araC (cytabarine)
A
decreased levels of
4
Q
____ a GNRH analog is used to treat metastatic protstate cancer by gonadal adrenal inh
A
Leuprolide (dec Testostreone levels via cont. infusion)
5
Q
____ is used for breast cancer and competes for estrogen receptors
A
tamoxifen (pre-menopausal women)
6
Q
Tamoxifen is for ER pos tumors but can cause
A
thromboembolism + endometrial cancer
7
Q
HOw to treat CD20+ B cell lymmphoma
A
Rituximab
8
Q
Trastuzumab used to treat
A
HER2/eu cancer
9
Q
Dactinomycin works by blocking
A
PD1 receptor
10
Q
Tamoxifen is anti estrogen and pro estrogen where?
A
anti in breast; pro in endometrium + bone
