Unit 2 - part 1 Flashcards
What are the 3 NORMAL layers of oral mucosa?
Oral Epi (OE) Lamina Propria (gingival connective tissue) Submucosa
_______ tissue covers the hard palate and the attached and free gingiva?
Masticatory
The cheeks and the soft palate are covered with _____ mucosa
lining
Non-Masticatory mucosa covers what surfaces?
Vestibules Alveolar Mucosa
All cellular mitosis occurs where?
Basal Lamina
What structure separates the OE from the connective tissue?
Basement Membrane
What term is used to describe the process of cellular growth going from the bottom layer (basement membrane) up to the surface?
Orthokeratinization
Cells form on the _____ _______ and are seen as round cells?
basal lamina
Cells go from being round in shape to being “squished” and have projections (desmosoomes) sticking out of them….this layer is called the?
Prickle layer
What layer comes after the prickle layer?
Granular layer
What is the 4th layer called and what type of tissue has a 4th layer?
Keratin Layer Masticatory
The average amount of days for a cell to go from “birth” to “death” is?
25 days
The lamina propria contains what cells?
Fibroblasts Macrophage Mast
The submucosa contains?
salivary glands blood vessels muscles
What is the term for a epithelium projection into the connective tissue?
Rete Pegs
What is a common area to have hyperkeratosis?
Linea Alba (cheek bite)
Why does hyperkeratosis appear white in the mouth?
because it absorbs more fluid and reflects back a white color
What is the fancy name for a cheek bite?
Morsicatio Buccarum
71% of all white lesions of the oral mucosa are?
Benign Hyperkeratosis
A _______ is a white, opaque, leathery lesion NOT clinically identifiable from other white lesions?
Leukoplakia
If someone has a white lesion in ________ it automatically needs to be biopsied and taken care of cause it isn’t normal?
floor of mouth
A dysplastic leukoplakia is a white spot with ________
dyskeratosis
Dyskeratosis is often associated with?
malignancy
A THIN white keratotic film usually over the lower lip is termed a?
Solar Cheilosis
Solar Cheilosis predisposes to?
cancer of lip
What is the most common zone for skin cancers?
Ala-traga zone (head of bald guys also)
Solar Cheilosis is also called?
Actinic keratosis
White sponge nevus is a ________ keratosis with a _________ white folded ________
congenital familial gingivostomatitis
White sponge nevus always involves the ?
cheek mucosa
Microscopically the white sponge nevus will have ________edema with broad fused _____ ______?
prickle cell rete pegs
Is White Sponge Nevus harmless or harmful?
harmless
What is a term for a white/gray layer of clear, thin, non wrinkled mucosa?
Leukodema
What lesion found in the mouth is USUALLY found on flexor surfaces of arms and legs?
Lichen Planus
The term for the raised white lines and dots (zig-zag “cracks”) found in Lichen Planus?
Wicham Stria
Lichen Planus is due to?
over-correction of inflammatory response
Lichen Planus is seen microscopically with extensive _________ infiltration, liquefaction of ________, and a prominent ______ layer
lymphocyte basal layer granular
When you have Wicham Striae the lesion is called a ________ lichen planus
reticular
______ Lichen Planus is characterized by painful, burning ulcer patches?
Erosive
What is the tx/fix for Lichen Planus?
No TX just let it run its course
Nicotine Stomatitis is found where?
palate
What is the etiology of Nicotine Stomatitis?
heat and tar irritant from smoking
Nicotine Stomatitis is sen clinically with _______ that have a central _______ corresponding to the inflamed _______?
papule red accessory saliva glands
Name this lesion that is caused by heat and irritants from smoking
Nicotine Stomatitis
This lesion is exacerbated by emotional stress and is seen microscopically with a prominent granular layer
Erosive Lichen Planus
This lesion is congenital and has a edematous prickle cell layer
White Sponge Nevus
This lesion is commonly found in the ala-traga zone
(Skin flakes off then comes back flaky again)
Actinic Keratosis
What is this lesion called? What are the white “cracks” called?
Reticular Lichen Planus
Wicham Striae
This lesion is often found on lower lip and predisposes to cancer
Solar Cheilosis
This type of white lesion is associated with malignancy and has dyskeratosis microscopically
Dysplastic Leukoplakia
This lesion is pre- ________ and has a _____% chance of progressing into a carcinoma
malignant
90
Is this normal?
What is it called?
YES
Cheek Bite (Morsicatio Buccarum)
What do we call a RED lesion when we dont know the cause?
Erythoplakia
There are currently ______ forms of Herpes?
8
What is the term for a FIRST encounter breakout of Herpes?
Primary Herpetic Gingivostomatitis
80% of the time is is herpes ___ or ___ when found in the oral cavity?
1
2
Which herpes simplex virus comes back more often?
2
What herpes virus causes Kaposi’s sarcoma?
CMV Cytomegaly Virus
Epstein-Bar virus causes what common disease?
Infectious Mononucleosis
Recurrent Herpes lesions or commonly called _____ ______ are __ lesions that are found on the _____ gingiva?
Cold Sores, Fever Blisters etc.
single
attached
Where does the herpes virus live while dormant?
Trigeminal Ganglion
A cold sore lasts how long?
7-14 days
Herpes Zoster or _______ affects what age group?
Shingles
60 and over
Shingles is preceded by ______ and comes from the ______ region affecting the _____?
pain
spinal
trunk
What is the etiology of Shingles?
Vericella zoster (chicken pox)
What is the term for a canker sore?
Apthous ulcer
Canker sores appear on the _____ side of the mouth on the _______ gingiva?
wet
unattached
What is the term for herpes under the nail bed?
Herpetic Whitlow
The etiology of a canker sore is ______ but probably due to?
unkown
immune reaction to hemolytic strep
TB is a ______ associated disease?
lung
If TB affects the mouth it looks like an _____ or an ____ of the mucous membrane?
abcess
ulcer
What is the tx for someone who gets TB?
INH therapy
(6 mo antibiotic therapy)
What is the pathognomonic for syphilis?
Spirochete-treponema pallidum
What accompanies the primary syphillis stage?
Big Chancre for 2-3 wks
The secondary stage of syphilis is affiliated with?
Flue-like symptoms with a mucous patch
(weeks/months later)
What is the tertiary (3rd) stage of syphilis affiliated with?
Gumma (rubbery lesion in palate)
Glossitis
Death!!!
(1-20 yrs later)
What is the most common fungal infection in the oral cavity?
Candidiasis
Oral Candidiasis is often called _______ and has a smooth, _____ or ____ plaque that _____be wiped off?
thrush
white
yellow
can
What will the tissue look like if a yeat infection has been wiped away?
Red (on fire)
Older people who get thrush can present with?
Angular Cheilitis
What is the term for a common wart in the oral cavity?
Oral Verruca Vulgaris
What is a wart in the oral cavity caused by?
HPV
What age is the peak time to get a HPV vaccination?
11
What strains of HPV cause genital/oral warts?
6 And 11
What strains of HPV cause cervical cancer?
16, 18
Fordyce Granules are a _______ condition that presents as ectopic ______glands found in the _____ _____ of the mucosa?
normal
sebaceous (oil)
lamina propria
What is a raised, white irregular line on the buccal mucosa at occlusal plane level that CAN’T be wiped off?
Linea Alba
What is a white-grey film “saran-wrap” look to the buccal mucosa that CANT be wiped off?
Leukoedema
What are yellow creamy spots cound mostly in buccal mucosa with preponderance in males?
Fordyce Granules
What is the name for Cheek Biting?
Morsicatio Buccarum
What are two common causes of CHEMICAL burns of the mouth?
Bleach
Asprin
Chemicals burn mucosa either through ____ or _____ reactions?
Systemic (allergic)
local
What is an inherited disease resulting in clusters of capillaries with enlarged ends?
Hereditary Telangectasia
