Unit 2 exam: Hair,Skin,Nails Flashcards
4 reasons why we look at skin
- Indicator of overall health
- Systemic chronic disease process can have skin manifestations
- Acute disease process of skin
- Chronic skin conditions
4 functions of skin
- Boundary for fluids
- Protection: from microorganisms, harmful substances, radiation
- Modulate body temperature
- Synthesizes vitamin D
layers in the epidermis and dermis
Epidermis
horny layer: keratinized cells (stratum corneum)
cellular layer: stratum basale and stratum spinosum, where melanin and keratin are formed
Dermis
Provides nutrition for the epidermis
Connective tissue, sebaceous glands, sweat glands, lymph vessels, and hair follicles
(supplied by vessels in sub Q)
skin color: carotene, deoxyHg and oxyHg
Carotene
-Golden yellow pigment that exists in the fatty layer and in highly keratinized layers
Oxyhemoglobin
-Hemoglobin carries oxygen in the blood; bright red w/ full O2. Increase of blood = redness, decrease=pallor
Deoxyhemoglobin
-low O2,darker and bluer pigment. Increased content in cutaneous blood vessels causes cyanosis
two types of cyanosis
Central- low level of oxygen in arteries
Peripheral- normal level of arterial oxygen; caused by the blood slowing down in cutaneous vessels and more Oxygen being extracted making it appear more blue.
4 appendages of skin
hair (vellus & terminal (thick, post-puberty)), nails, seb glands, sweat glands
apocrine glands
type of sweat gland: open into follicle, axilla & genital area, make body odor
how much of the nail is under the proximal nail fold?
1/4 (nail root)
angle between nail fold and plate is less than…
180 degrees
how many people get skin cancer in the US?
1 in 5
basal vs squamous vs melanoma (% of skin cancers, chances of metastasis)
basal (80%, dont metas. often)
squamous (16%, rarely metas.)
melanoma (4-5%, deep in lymph, metas. often)
basal vs squamous vs melanoma (cell types)
basal: cells resembling basal layer epidermis
squamous: cells resembling spinous layers of epidermis
melanoma: melanocytes in epidermis
ephelides
a freckle is caused by an over production of melanin which accumulates under the skin. NOT an overabundance of Menalocytes which is a mole or nevi.
3 most common nevi/mole types
Junctional nevi- brown macules in the epidermis
Compound nevi- brown macules? (dome shaped, elevated), in both epi and dermal layers
Intradermal nevi- skin colored papules in the dermis
risk factors for melanoma
H: History of previous melanoma A: Age over 50 R: Regular dermatologist absent M: Mole changing M: Male gender