the pregnant woman Flashcards
what does estrogen do? (3)
- Endometrial growth supports early pregnancy
- Stimulates prolactin from anterior pituitary: readies breast tissue for lactation
- Contributes to a hypercoagulable state that increases risk of thromboembolic events
which hormone dominates the beginning of the menstrual cycle?
estrogen
what does progesterone do? (3)
- Increase tidal volume and alveolar minute ventilation; leads to resp. alkalosis and SOB sensation
- Esophageal sphincter tone decreases: gastroesophageal reflux— ( works with estradiol)
- Relaxes tone in ureters and bladder: hydronephrosis and risk of bacteruria
what does HCG do?
Produced by the placenta supports progesterone synthesis in corpus luteum preventing the early embryo being lost to menstruation
- (AKA supports pregnancy until the pregnancy can support itself- keeps placental supported by progesterone)
***what hormone is implicated in the insulin resistance and hyperglycemia associated with gestational diabetes?
human placental lactogen
***___ of all women with GDM will go on to have _____ ______ _____ in their lifetime
half
type 2 DM
if a woman has GDM in first pregnancy? will she likely have it in her second? what are the babies like?
yes!
babies are big
how do thyroid hormones (T3, T4, TSH) levels change in pregnancy?
fluctuate, usually normal ranges, due to HCG’s stimulation of TSH receptor
what secretes relaxin? what does it do?
Secreted by corpus luteum and placenta
- Promotes ligamentous laxity in the SI joints and pubic symphysis in preparation for passage of the fetus
when does erythropoeitin levels increase? what does this do?
Increases during pregnancy raising erythrocyte mass
- Plasma volume increases causing relative hemodilution and physiologic anemia
- CO increases but systemic vascular resistance decreases: net decrease in BP
what anatomic changes happen to the breast in pregnancy? (4)
- Moderate enlargement due to hormonal stimulation increased vascularity and glandular hyperplasia
- Nipples larger and more erectile, darker areola and pronounced Montgomery glands
- Increased venous pattern
- 2nd and 3rd trimester colostrum secretion; a nutrient rich precursor to milk
what anatomic changes happen to the uterus in pregnancy? (3)
- increases in size: Muscle cell hypertrophy
- Increase in fibrous and elastic tissue
- Development of blood vessels and lymphatic
in the ___ trimester, Uterus confined to pelvis
and Retains prior position
first
what happens to the uterus/ b/c of the uterus in the second trimester ? (4)
- 12-14 weeks uterus becomes externally palpable above pelvic brim
- Starts to invade space for bladder
- Intestines are displaced laterally
- Stretching of round ligaments- mostly on the right side
___ wks the uterus is at the umbilicus level (to of the fundus palpable here)
20
___ wks the uterus is just above the pelvic brim (tops of fundus palpable here)
12 - 14
what are the breakdown of wks between first, second, and third trimester?
first: 0-12 wks
second: 13-28 wks
third: 29-40 wks
what anatomic changes happen to the vagina in pregnancy? (3)
- Chadwick’s sign
- Vaginal walls become more deeply rugated due to thickening of mucosa and loosening of connective tissue and hypertrophy of muscle cells
- Increase in glycogen stores in epithelium = proliferation of Lactobacillus acidophilus –> decrease vaginal pH
***what is chadwick’s sign ?
- increased vascularity leads to a bluish color of vaginal walls and cervix
what happens to the cervix in pregnancy?
- Chadwick’s sign- appears cyanotic
- Hegar’s sign
- Mucus plug fills the cervical canal to protect from
outside influence (protect from bacteria)
***what is hegar’s sign?
palpable softening of the cervical isthmus
what is the first thing “to go” in delivery?
mucus plug of the cervical canal
might be able to feel ______ ______ as a small nodule that then disappears by _________
Might be able to feel corpus luteum as a small nodule then disappears by mid-pregnancy
(changes in the adnexae in pregnancy)
what happens to the external abdomen in pregnancy?
- Stria gravidarum (stretch marks)
- Linea nigra- a brownish black line along the midline
- Diastasis recti- rectus abdominis muscles may separate
what is the cervical isthmus? (kinda weeds)
the uterine isthmus is the inferior-posterior part of uterus, on its cervical end — here the uterine muscle (myometrium) is narrower and thinner. It connects superiorly-anteriorly to the complementary parts of the uterus: the body and the fundus
what is the adnexae?
The appendages to the uterus are known as the adnexa uteri. The parts of the adnexa uteri are the fallopian tubes, ovaries, and ligaments
looking at a quantitative HCG: know where they should be (baseline) based on what?
dates of last menstrual cycle
if HCG higher than what you expect, what does this mean?
they have twins or they further along in the pregnancy than they thought they were (a month or so earlier)
if pregnancy is viable, what number do we want to go up?
HCG hormone levels
what test do we do to confirm pregnancy?
urine HCG (maybe blood HCG but not really necessary)
health history for pregnancy (6)
- Current state of health
- Past obstetric history
- Past medical history
- Family history
- Expected weeks of gestation (first day of LMP- last menstrual period)
- Expected date of delivery (Naegele’s rule)
acute/chronic issues that effect pregnancy (weeds)
Abdominal surgeries Hypertension Diabetes Cardiac conditions Asthma Hypercoagulability states Mental health disorders HIV/STIs Abnormal Pap smear
how do you ask for the expected weeks of gestation?
first day of LMP (last menstrual period)
what is “ G” (gravida)?
how many prior pregnancies you have had
what is the “P” (para/ parity) ?
how many labors you have had. includes term deliveries, preterm, spontaneous/therapeutic abortions
what are pregnancy complications that you may ask history about? (4)
DM, HTN, preeclampsia, preterm labor
what are labor or delivery complications that you may ask history about? (3)
Large babies, fetal distress, emergency interventions
what are risks to maternal and fetal health? (weeds)
Tobacco, alcohol, illicit drugs
Medications, OTC medications, Herbal
Toxic exposures at home or work? (Cat litter)
Nutritional intake
Adequate social support and financial support
Stress at home or work
Physical abuse or domestic violence
what does “TPAL” stand for?
T- term (to 20 wks)
P- preterm
A- abortion (spontaneous or therapeutics)
L- living
***what is naegele’s rule?
Estimated Date of Delivery (EDD): Add seven (7) days to first day of LMP Subtract three (3) months Add one (1) year
for family history, how far along in the family tree do you ask about?
2 generations up and 2 generations down
if there is a congenital problem/anomaly in the first child is it more likely that their second will have it?
yes
what do babies get from breastmilk that they can’t with formula?
Passive immunity from certain infectious diseases until their own immunity is functional at 3-4 months
gestational age is used to establish timeframe of the pregnancy. what information is this useful for? (5)
- For normal progress
- Establishing paternity
- Timing screening tests
- Tracking fetal growth
- Effective preterm and postdates labor