Unit 2 Flashcards
Reproduction
the production of a new generation of cells or individuals
DNA
Deoxyribonucleic acid, a double-helix structure composed of nucleic acids which acts as the instructions or template for the manufacture of proteins
Chromosome
A DNA molecule and the proteins associated with it
Genes
A specific region of a DNA strand (or chromosome) that inheritable trait(s)
Gene locus
location of a gene on the chromosome
Somatic
those cells which comprise an organism’s tissues & replicate by mitosis
Germ
those cells which will form gametes by meiosis
Zygote
the cell formed when two gametes fuse
Mitosis
A one-stage nuclear division process in which the diploid number of chromosomes is maintained in each in each of the daughter cells
Diploid
having 2 chromosomes of each type, a pair of homologous chromosomes; one maternal & one paternal
Haploid
having one chromosome of each type; either one maternal or one paternal
Functions of mitosis
Replacement of cells, growth in multi-cellular organism, asexual reproduction
Cellular differentiation
all somatic cells contain the same genetic info but have the ability to differentiate
Stem cells
undifferentiated cells that maintain ability to divide
Telomeres
repeating nucleotide sequences at chromosome tips
Kinases & Cyclins
intracellular proteins that control cell division
Cell size
division occurs to maintain favorable surface to volume ratio
Hormones examples& how it’s delivered
prolactin, estrogen: through the circulatory system
Growth factor example& where it works
epidermal growth factor: near the site of synthesis
Density-dependent inhibition
cell stops dividing when compressed agaisnt others
Tumor suppressor genes
controls mitosis (e.g BRCA1 & BRCA 2 stops breast cancer)
Characteistics of Cancerous Cells
abnormal anatomy&phsyiology, accelerated mitotic rate, migration into tissues (local or remote)
Dysplatic cells
cells irregular in anatomy but in their normal situation. Normal mitotic rate
Neoplasm(Tumor)
disorganized mass of irregular cells w/ increased mitotic rate
Benign
lump-like mass of cells compressing surrounding tissue. frequently encapsulated, slow growing & has not yet invaded other tissues(ex. fibroadenome which affects 10% of women)
Malignant
mass of cells that invade surrounding tissues, not encapsulated and frequesnt growing
Metastasis
malignant cells travel to other tissues via blood or lymph & secondary malignant tumors
Causes of cancer- carcinogens examples
smoking, fats, radiation, viruses, saccharine, some natural foods, mechanical compression-denture wearers and pipe smokers
Causes of cancer- oncogenes
genes that cause cancer like BrCa1, BrCa2
Mutated tumor suppressor genes
genes that regulate mitosis. when mutated, fail to control mitosis
Metabolism
the total of all chemical reactions w/in a cell
Anabolism
dehydration synthesis yields a larger molecule from smaller molecules like glycogen formation
Catobolism()cellular respiration
a decomposition reaction(hydrolysis) that yields smaller molecules from larger & relieases like starch breakdown
Respiration
the process that releases energy from molecules breakdown
Kinetic energy
performing work(energy in action) like roller coaster in motion
Potential energy
that is stored & has future work potential due to chemistry or loaction like fat. ball at the top of stairs