Unit 12 Flashcards
What are the defining properties of stem cells?
unspecialized
perpetual self-renewal
ability to differentiate into a specialized cell
Types of stem cells from most unspecialized to specialized.
totipotent pluripotent multipotent omnipotent unipotent fully diffrentiated
Properties of totipotent cells
can self-renew by dividing
develop into early embryo and extraembryonic tissues (ex. placenta)
can differentiate into all the cells
EXAMPLE: cells in zygote in first few divisions
Properties of pluripotent cells
can self-renew by dividing
develop into the 3 primary germ layers of the embryo
can’t give rise to extraembryonic tissues
EXAMPLE: becomes any cell except extraembryonic tissues
Properties of multipotent cells
least plasticity
currently in us
can self-renew
develop into a limited number of specialized cells related to original tissue or organ
EXAMPLE: stem cells in bone marrow can differentiate into dif types of blood cells.
What is the epigenome?
The “layer” of chemicals on the nucleosome (DNA-histone complex)
What is acetylation?
Chemicals called acetyl groups attach to the histones causing the histones to loosen their grip on the DNA.
Increases transcription
What is methylation?
Chemicals called methyl groups attach to the histones causing the DNA to be tightly wound.
Decreases transcription
How do cells differentiate?
During different cell divisions, only certain parts of the genetic information is used.
Genes are turned on and off in a particular sequence
What is cell differentiation?
Cellular differentiation is the transformation of unspecialized cells called stem cells into specialized cells that carry out a particular task in the body.
What are tissues?
Collections of related cell types that work together to carry out a specific function
Explain muscle tissue
Contractile tissue
Produces movement of the body or its parts
Includes smooth, skeletal, and cardiac muscle
Explain epithelial tissue
Lining tissue
Covers the body and lines internal surfaces
Can be modified to perform specific roles
Explain nervous tissue
Receives and responds to stimuli
Makes up the structures of the nervous system
Regulates function of other tissues
Explain connective tissue
Supports, protects, and binds other tissues
Contains cells in an extracellular matrix
Can be hard or fluid
What does CRISPR stand for?
Clustered Regularly Interspaced Short Palindromic Repeats
What is CRISPR?
A process that allows scientists to utilize the CAS9 protein to find and remove a specific part of DNA using a template DNA strand
What is CRISPR used for?
It can be used to detect and destroy DNA to edit the genome.
What molecule is used to find a particular sequence of DNA?
an RNA sequence
What molecule is used to cut DNA?
CAS9 (enzyme)
Functions of pancreas
Make digestive juices / Produces enzymes that break down carbs, proteins, lipids, and nucleic acids
Produces hormones that regulate blood sugar levels
Produces sodium bicarbonate, a base that neutralizes stomach acid that allows enzymes to be effective
Function of liver in digestion
Produces bile, which is loaded with lipids and salts
Function of gallbladder
Stores bile
Functions of brain
Relay messages
Process / analyze information
Control almost all bodily functions
Positive feedback
The response strengthens the change in a controlled condition (enhances the change)
Negative feedback
The response reverses a change in a controlled condition (counteracts the change)
What organs make up the nervous system
Brain, spinal cord, peripheral nerves