Unit 1: Risk, Health, and Lifestyle Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What do carbohydrates consist of?

A

A chain of single units called saccharides contains only carbon, hydrogen and oxygen.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What id the difference between different types of saccharides?

A
Monosaccharides= single sugar monomer
Disaccharide= two monosaccharides 
Polysaccharides= many monosaccharides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How are di and polysaccharides formed

A

Monosaccharides join to form di and polysaccharides through a condensation reactions (a water molecule is released). Glycosidic bonds are formed. It can be broken by adding water (hydrolysis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Give 2 examples of monosaccharides and their function.

A

Glucose has six carbon atoms and is the main substrate for respiration.
Ribose has five carbon atoms and is a component of DNA and RNA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Give three examples of disaccharides and their component of monosaccharides.

A

Maltose (two glucose molecules)
Sucrose (glucose and fructose)
Lactose (glucose and galactose)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give two examples of polysaccharides and their function

A

Glycogen (animals) and starch (plants). They are both energy storing molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Structure of glycogen and its function

A

Highly branched, this means that the molecule can be easily hydrolysed to release energy quickly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Relate starch’s structure to its function.

A

Mixture of two polysaccharides.
Amylose= coiled to make the molecule compact, so large amounts of it can be stored.
Amylopectin= highly branched, so energy can be released quickly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How is a triglyceride formed

A

One molecule of glycerol forms ester bonds with three fatty acids through a condensation reaction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How to differentiate between saturated and unsaturated fats.

A

Saturated fats have no C=C bonds. They are solid at room temperature due to strong intermolecular forces.
Unsaturated fats have one or more C=C bonds and are liquid at room temperature due to weak intermolecular forces.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is meant by a high-density lipoprotein?

A

Made of triglycerides from unsaturated fats combined with protein. They reduce blood cholesterol levels by transporting it to the liver to be broken down. They are know as the ‘good’ lipoproteins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is meant by low-density lipoprotein?

A

Made of triglycerides from saturated fats combined with a protein. These block receptor sites, reducing the cholesterol absorption. These are know to be the ‘bad’ lipoproteins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do LDLs contribute to the risk of cardiovascular disease?

A

The high blood cholesterol levels caused by LDLs leads to the formation of plaques (atherosclerosis). This is a casual relationship (as one increases the risk increases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the properties of water.

A

It is essential for all metabolic processes. One oxygen and two hydrogens, with covalent bonds. All water molecules are held together by strong hydrogen molecules. Due to their polarity and ability to form hydrogen, excellent solvent for polar as well as ionic substances. High specific heat capacity (temperature stabiliser in living bodies). High vaporisation as heat sinks for living bodies- cooling. It is an excellent lubricant providing cushion effect on vital organs. Ideal for transporting and reaction medium. Dissolve- electrostatic forces broken

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The veins, arteries and valves going in a clockwise direction of the heart

A

Pulmonary artery, pulmonary vein, atrioventricular valve, semi-lunar valves, cords (valve tendons), semi-lunar valves, atrioventricular value, inferior vena cava, superior vena cava, artery.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In a clockwise motion, what are the 4 chambers?

A

Left atrium, left ventricle, right ventricle, right atrium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What do different parts of the heart do (ventricles and valves)?

A

The left ventricle of the heart has a thicker, more muscular walls than the right ventricle, because it needs to contract powerfully to pump blood all the way around the body, while the right needs to transport it to the lungs, which are close by.
The ventricles have thicker walls than the atria, because they have to push blood out of the heart whereas the atria just need to push the blood a short distance into the ventricles.
The atrioventricular valves link the atria to the ventricles and stop blood flowing back into the atria when the ventricles contract. Cords attach the atrioventricular valves to the ventricles to stop them from being forced up into the atria when the ventricles contract.
Semi-lunar valves link the ventricles to the pulmonary artery and the aorta, and stop the blood flowing back into the heart after the ventricles contract.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How do valves help blood flow in one direction?

A

The valves only open one way- whether they are open or closed depends on the relative pressure of the heart chamber. If there is a high pressure behind the valves, it is forced open, but if there is high pressure in front of the valve it’s forced shut.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Describe and explain the arteries

A

They carry the blood from the heart to the rest of the body. They’re thick-walled, muscular and have elastic tissue in the walls to cope with the high pressure cause by the heartbeat. The inner lining (endothelium) is folded, allowing the artery to expand- this also help with high pressure. Narrow lumen (space in centre for blood to flow through).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describe and explain the veins

A

They take blood back to the heart. They’re wider that the equivalent arteries, with very little elastic or muscle tissue as the blood is under lower pressure. Veins contain valves to stop the blood flowing backwards. Blood flowing through the veins is helped by contraction of the body muscles around them. (wide lumen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Describe and explain capillaries

A

They are the smallest of the blood vessels. They were metabolic change occurs- substance are exchanged between cells and the capillaries. There are a networks of capillaries. These network of capillaries in tissue (called capillary beds), which increase the surface area for exchange. Capillary walls are only one cell thick, which speeds up the rate of diffusion of substances (e.g. glucose and oxygen) into and out of the cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Ventricular diastole, atrial systole

A

The ventricles are relaxed. The atria in contract, decreasing the volume in the chambers and increasing the pressure inside the chambers. This pushes the blood into the ventricles. There’s a slight increase in ventricular pressure and chamber volume as the ventricles receive the ejected blood from the contracting atria.

23
Q

Ventricular systole, atrial diastole

A

The atria relax. The ventricles contract, decreasing the volume and increasing their pressure. The pressure becomes higher in the ventricles than the atria, which forces the AV (atrioventricular valves) valves to shut to prevent back flow. The pressure in the ventricles is also higher than in the aorta and the pulmonary artery, which forces open the SL (semi lunar) valve and the blood is forced out of the arteries.

24
Q

Cardiac diastole

A

The ventricles and the atria are both relaxed. The higher pressure in the pulmonary artery and the aorta closes on the SL valves (semi lunar valves) to prevent back flow into the ventricles. Blood returns to the heart and the atria fills up again due to the higher pressure in the vena cava and the pulmonary vein. In turn this starts to increase the pressure of the atria. As the ventricles continue to relax, their pressure falls below the pressure of the atria and so the AV valves (atrioventricular valves) open. This allows blood to flow passively (without being pushed by atria contraction) into the ventricles from the atria. The atria contract and the whole process begins again.

25
Q

What is endothelium?

A

It is the lining of blood vessels

26
Q

Properties of water

A

The hydrogen end is positive and the oxygen is negative. Many chemicals can be dissolved into it allowing biochemical reactions to take place. It is a liquid medium which will provide habitats and for chemical reactions to take place. Important metabolite, which is used in hydrolyse and condensation reactions. High specific heat capacity, which will keep aquatic and cellular environments stable. High latent heat of vaporisation, which will have a cooling effect on an organism. Cohesion of molecules, used in plants as water is drawn up the xylem. Surface tension, which allows pond-skaters to walk on the surface. Good solvent and reaction medium. Incompressible, which can prevent plants from wilting and act as hydrostatic skeleton for invertebrates.

27
Q

Investigating heart rate: Daphnia practical

A

1) Make up a range of caffeine solutions of different concentrations and a control solution that has no caffeine at all.
2) Transfer one Daphnia on into a dimple on a cavity slide (placed on a cotton wool to limit movement.
3) Using a pipette, place a few drops of caffeine solution into the Daphnia starting with the lowest concentration and wait 5 minutes
4) Place the slide onto the stage of a light microscope and adjust the focus so you can see the heart beating.
5) Count the number of beats using a tally (pencil and paper) in 20 seconds using a stopwatch and multiply this by 3 to get the beats per minute.
6) Repeat this 3 times with different Daphnia with the same concentration.
7) Repeat using the other concentrations and the control
8) Compare results of the caffeine and heart rate.
Plot this on a graph with the average of the 3 readings. Plot average heart rate against concentration of caffeine. Positive correlation- increase caffeine, increase heart rate.

28
Q

Ethical issues using invertebrate

A

Experimenting on animals allows use to study things that would be unethical to study on humans but people argue it is still unethical as animals cannot consent to the painful procedures.
Some people believe it is more acceptable to experiment on invertebrate (Daphnia, spiders) than vertebrate (dogs, monkeys). This is because they are considered a simpler organism like less sophisticated nervous system.
However some still see this as unethical as the experiments cause distress or suffering.

29
Q

Most cardiovascular diseases start with atheroma, what is the formation of atheroma?

A

1) Arteries made up of several layers
2) Endothelium- smooth and unbroken
3) Damaged- inflammatory response
4) White blood cells and lipids from the blood, go under the endothelium to form fatty steaks.
5) More white blood cells, lipids and connective tissue- build up and harden- fibrous plaque (atheroma)
6) Partially blocks the lumen of the artery and restricts blood flow- blood pressure increases.
7) Hardening arteries caused up atheroma is called atherosclerosis

30
Q

How does atheroma increase the risk of thrombosis in arteries?

A

1) Atheroma develops in the wall of the arteries
2) Rupture the endothelium- damaging the artery- rough surface
3) Triggers thrombosis (blood clot) to form at the site
4) Blood clot can cause a complete blockage or can become dislodged (block somewhere else in the body).
5) Blood flow to tissue is restricted- less oxygen = damage
6) Heart attack, stoke, deep vein thrombosis (cardiovascular disease from blood clots)

31
Q

How does a blood clot form?

A

1) Protein called thromboplastin is released from the damaged blood vessel.
2) (+calcium ions) Triggers the conversion of prothrombin (soluble protein) into thrombin (enzyme)
3) Thrombin catalyses the conversion of fibrinogen (soluble protein) to fibrin (insoluble fibres)
4) Fibrin fibres tangle together to form a mesh in which platelets and red blood cells get trapped (blood clot)

32
Q

How does a blood clot cause a heart attack?

A

1) Heart muscle supplies blood to the coronary arteries.
2) Contains oxygen to carry out respiration
3) Completely blocked from a blood clot- cut off from blood supply- won’t receive oxygen.
4) Myocardial infarction - heart attack
5) Large areas of the heart affected - complete heart failure- fatal
6) Symptoms- pain in chest and upper body, shortness of breathe, and sweating
7) Heart attack- damage and death to heart muscle
Coronary Heart disease (CHD) have lots of atheroma - restrict blood flow- increase risk of blood clot- increased risk of a heart attack

33
Q

What is a stoke?

A

Rapid loss of brain function due to a disruption in the blood supply to the brain. Blood clot in the artery leading to the brain, reduces blood and therefore oxygen.

34
Q

What is deep vein thrombosis?

A

DVT formation of a blood clot in a vein deep in the body usually the leg. Caused by prolonged inactivity- long hauled flights and risk increases with age.

35
Q

What are the lifestyle choices that increase the risk of CVD?

A

1) Diet- high in saturated fats- increase blood cholesterol level- increase atheroma formation. High in salt- high blood pressure.
2) High blood pressure- increase risk of damage to the artery walls, increase risk of atheroma formation. Excessive alcohol consumption, stress and diet
3) Smoking- Carbon monoxide- combine to haemoglobin, reduce the amount of oxygen, reduce oxygen available to tissue. Nicotine- platelets sticky, blood clots forming. Decreases the amount of antioxidants- cell damaging the artery walls- atheroma formation.
4) Inactivity- lack of exercise- increases blood pressure

36
Q

What are the factors beyond your control that increase the chance of CVD?

A

1) Genetics- predisposed to a high blood pressure or high cholesterol level
2) Age- chance increases with age- plaque builds up with age
3) Gender- men are three times more likely to suffer from CVD- different levels of hormones - oestrogen (increases level of ‘good’ cholesterol (HDLs)

37
Q

How can the perception of risk be different form the actual risk?

A

People overestimate the risk- greater risk than they actually are- media- constant exposure to information can make people constantly worry
People underestimate risk- lower risk than they actually are due to a lack of information

38
Q

Evaluate the use of Antihypertensives.

A

Drug. Beta -blockers (reduces the strength of the heartbeat) and vasodilators (widen blood vessels). Diuretics- reducing the amount of sodium that is reabsorbed by the blood in the kidneys- less water absorbed (osmosis), reduce blood volume. Reduce blood pressure, less chance of damage, reducing the risk of forming atheroma and blood clots.
Benefits:
- Different types work in different ways, given in combination to reduce blood pressure, blood pressure monitored at home
Risks:
- Palpitations, abnormal heart rhythms, fainting, headaches, drowsiness, blood pressure becoming too low, allergic reaction, depression

39
Q

Evaluate the use of Statins.

A

Reduce blood cholesterol levels by reducing the amount of ‘bad’ cholesterol (LDLs) produced in the liver, reduces atheroma formation.
Benefits:
- Reduce risk of developing CVD
Risks:
- muscle and joint pain, digestive system problems, increased risk of diabetes, nosebleeds, headaches and nausea

40
Q

Evaluate the use of anticoagulants

A

Warfarin and heparin. Reduce blood clotting, reduce where arteries become damages, less chance of a blood vessel becoming blocked.
Benefits:
-Used on people who already have blood clots or CVD- prevent existing blood clots from growing larger and new ones forming. Can’t get rid of existing blood clots.
Risks:
- Injured, reduction in blood clotting cause excessive bleeding- fainting, death. Allergic reaction, osteoporosis (weakened bones), swelling of the tissue, damage to foetus is pregnant.

41
Q

Evaluate the use of platelet inhibitory drug

A

Aspirin. Prevent platelets from sticking together, reduce formation of blood clots.
Benefits:
- Can be used to treat those who already have blood clots or CVD
Risks:
- Rashes, diarrhoea, nausea, liver function problems, excessive bleeding (especially after a serious injury)

42
Q

What does energy budget mean?

A

It is the term used to describe the amount of energy taken in by an organism and the amount of energy used up by an organism. Ideally organism should take in as the same amount as they use, imbalance effects someone’s weight

43
Q

What does weight gain mean in term of energy?

A

Energy intake is higher than that of energy output. Excess energy, causing fat reserves, gain weight. Energy difference is a lot and is sustained over a long period of time- obese

44
Q

What does weight loss mean in term of energy?

A

Energy intake is lower than that of output, body will to get more- fat reserves- lose weight. Energy difference is large and is sustained over a long period of time, the person is likely to become underweight.

45
Q

The vitamin C and DCPIP experiment

A

1) Make up several vitamin C solutions of different, known concentrations (six)
2) Measuring cylinder to measure out a set amount of DCPIP (a blue dye that turns colourless when presented with vitamin C) (at a set concentration) into a test tube.
3) Add one of the vitamin C solutions to the DCPIP drop by drop
4) Gently shake the test tube for a set amount of time, using a stopwatch
5) When the solution turns colourless record the volume
6) Repeat the experiment twice more with the same solution, take an average reading
7) Keep all variables constant like temperature
8) Repeat with each solution
9) Curve of best fit - calibration curve

46
Q

What are carbohydrates?

A

Large, long chains of monosaccharides like starch. Glucose in a monosaccharide with six carbon atom in each molecule. Two types of glucose- alpha and beta. Glucose structure relates to its function as the main source of energy in animals and plants. Soluble so it is easily transported, chemical bonds contain a lot of energy.

47
Q

How are monosaccharides joined together to form disaccharides and polysaccharides?

A

Monosaccharides are joined together by glycosidic bonds in a condensation reaction between hydrogen atom and a hydroxyl group, releasing a water molecule. Hydrolysis is the reverse, glycosidic bonds break apart. Two monosaccharides for disaccharide (maltose, lactose, and sucrose) - soluble and e their chemical bonds store more energy than monosaccharides. Polysaccharide is when more than two monosaccharides form (amylose, amylopectin, glycogen)

48
Q

What is starch?

A

Energy storage material in plants. Cells get energy from glucose- store excess as starch. Starch is a mixture of two polysaccharides of alpha-glucose. Amylose: unbranched chain, joined together with 1-4 glycosidic bonds, coiled structure, compact, good for storage, fit more in a small space. Amylopectin: branched chain of 1-4 and 1-6 glycosidic bonds. Side branches allows the enzymes to break down the molecule to get the glycosidic bonds easily. Glucose released quickly. Starch is insoluble in water, water can’t enter by osmosis, can’t swell, good for storage.

49
Q

What is glycogen?

A

Animals store excess energy of glucose as glycogen- another polysaccharide of alpha-glucose. It has 1-4 and 1-6 glycosidic bonds like amylopectin but it has loads more side branches, glucose released quickly (important), compact, insoluble, large molecule, so it can store lots of energy.

50
Q

What are triglycerides?

A

Kind of lipid. One molecule of glycerol with three fatty acids (long tails of hydrocarbons) attached to it. Tails are hydrophobic- insoluble. Fatty acids all consist of the same basic structure (1 carbon, 1 oxygen, 1 OH, 1 R group). R group tail varies.

51
Q

How are triglycerides formed?

A

By condensation reaction and broken up by hydrolysis. 3 fatty acids and the glycerol formed by ester bond. Hydrogen atom on the glycerol molecule bonds to a hydroxyl (OH) group on the fatty acid, releasing a water molecule. Reverse happen in hydrolysis- water molecule is added to the three ester bonds to break apart to make 3 fatty acids and one glycerol molecule.

52
Q

Lipids can be what?

A

Saturated (mainly found in animal fats like butter) or unsaturated (plants like olive oil- melt at lower temperatures than saturated). Difference is due to their hydrocarbon tails. Saturated: don’t have double bonds between the carbon atoms- every carbon has at least two hydrogen atoms. Unsaturated: have double bonds between carbon atoms, cause chain to kink. Two or more called polyunsaturated. A diet high in saturated fats increase blood cholesterol, increase risk of CVD.

53
Q

How does high blood cholesterol increase risk of CVD?

A

Cholesterol is a type of lipid. Some needed for the body to function normally. Cholesterols needs to be attached to protein to be moved around, so the body forms lipoprotein (substance composed of both protein and lipid) There are two types: High density lipoprotein (HDLs)- mainly protein , transport cholesterol from body tissue to the liver where it’s recycled or excreted, reduce blood cholesterol level when it is too high. Low density lipoproteins (LDLs)- mainly lipid, transport cholesterol from the liver to the blood, circulates until needed by cells, increases blood cholesterol level when too low. High total blood cholesterol (increase atheroma formation) level and high level level linked to increase risk of CVD

54
Q

How could you reduce the risk of CVD?

A

Diet- high in unsaturated fats, education, food manufactures label amount of saturated fats, informed choice. Obesity indicators: waist-to-hip ratio (waist/hips, more than 1.0 - carrying to much weight) and BMI (body mass/height - normal is between 18 and 25). To make an informed choice.
Smoking- advertise, free advice, prescribed nicotine patches
Exercise- exercise more frequently