Unit 1-Lecture 4 Flashcards
1
Q
Origin
A
Specific DNA sequence that will recruit helicase to start replication
2
Q
Leading strand
A
Moves in the same direction as the fork
3
Q
Lagging Strand
A
Moves in the opposite direction of fork
- Needs extra primers to catch up with leading strand
4
Q
Topoisomerase
A
Cuts both DNA strands in order to release tension
5
Q
Helicase
A
Unwinds DNA strands
6
Q
Primase
A
RNA Primer that acts as a starting point for DNA polymerase
7
Q
DNA Polymerase
A
Adds nucleotide bases
8
Q
Nuclease
A
Removes Primers
9
Q
Ligase
A
Connects fragments
10
Q
Replication Errors: Wrong Base Pairing
A
Hard to form bonds between wrong base pairs–>polymerization
11
Q
3’ to 5’ Exonucleolytic Proofreading Activity
A
Can remove a nucleotide
-will remove a wrong nucleotide more often than a right one
