Unit 1-Lecture 2

Question 1

Griffith Experiments

Answer 1

-studied pneumococcus
-smooth = virulent b/c of sugar coat
-rough = non virulent b/c no sugar coat

Question 2

Griffith Experiment Results

Answer 2

• smooth –> mice –> dead
  -heat killed smooth –> mice –> alive
  rough –> mice –> alive
• rough + heat killed smooth –> mice –> dead

Question 3

Why did rough + heat killed smooth kill the mice

Answer 3

The smooth bacteria TRANSFORMED the rough into smooth

Question 4

Avery, MacLeod, McCarthy Experiment

Answer 4

-made Griffith’s experiment more efficient by putting bacteria on plate instead of mice
-DNA is genetic material, people did not believe yet

Question 5

Hershey and Chase Experiment

Answer 5

-used phage to prove DNA is genetic material
-injected p32 virus DNA and s35 protein into bacteria only p32 was plated w/ bacteria

Question 6

Watson, Crick, Franklin

Answer 6

Created double helix model

Question 7

Chargaff’s Rules

Answer 7

• Amount of A bases is the same as T bases
  -Amount of G is the same as C
  -A+T and G+C are not the same