Unit 1 - Intro to the Clinical Lab (vocab) Flashcards

1
Q

accessioning

A

the process by which specimens are logged in, labeled, and assigned a specimen identification code

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2
Q

accreditation

A

a voluntary process in which an independent agency grants recognition to institutions or programs that meet or exceed established standards of quality

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3
Q

American Association of Blood Banks (AABB)

A

international association that sets blood bank standards, accredits blood banks, and promotes high standards of quality

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4
Q

anticoagulent

A

a chemical or substance that prevents blood coagulation

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5
Q

bacteriology

A

the study of bacteria

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6
Q

blood bank

A

clinical laboratory department where blood components are tested and stored until needed for transfusion; immunohematology department; transfusion services; also the refrigerated unit used for storing blood components

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7
Q

Centers for Disease Control and Prevention (CDC)

A

central laboratory for the national public health system

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8
Q

Centers for Medicare and Medicaid Services (CMS)

A

the agency within the Department of Health and Human Services (DHHS) responsible for implementing CLIA ‘88

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9
Q

Clinical and Laboratory Standards Institute (CLSI)

A

an international, nonprofit organization that establishes guidelines and standards of best current practice for clinical laboratories; formerly National Committee for Clinical Laboratory Standards (NCCLS)

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10
Q

clinical chemistry

A

the laboratory section that uses chemical principles to analyze blood and other body fluids

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11
Q

Clinical Laboratory Improvement Amendments of 1988 (CLIA ‘88)

A

a federal act that specifies minimum performance standards for clinical laboratories

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12
Q

coagulation

A

the process of forming a fibrin clot

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13
Q

College of American Pathologists (CAP)

A

organization that offers accreditation to clinical laboratories

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14
Q

COLA

A

agency that offers accreditation to physician office laboratories, hospitals, clinics, and other healthcare facilities; formerly the Commission on Office Laboratory Accreditation

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15
Q

Department of Health and Human Services (DHHS)

A

the governmental agency that oversees public healthcare matters; also called HHS

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16
Q

electronic health record (EHR)

A

comprehensive, portable electronic patient health record

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17
Q

electronic medical record (EMR)

A

a digital form of a patient chart created in a physician’s office or a hospital where a patient received treatment

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18
Q

epidemiology

A

the study of the factors that cause disease and determine disease frequency and distribution

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19
Q

Food and Drug Administration (FDA)

A

the division of the Department of Health and Human Services (DHHS) responsible for protecting the public health by ensuring the safety and efficacy of foods, drugs, biological products, medical devices, and cosmetics

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20
Q

Health Care Financing Administration (HCFA)

A

see Centers for Medicare and Medicaid Services (CMS)

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21
Q

hematology

A

the study of blood and the blood-forming tissues

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22
Q

HIPAA

A

Health Insurance Portability and Accountability Act of 1996

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23
Q

immunohematology

A

the study of the human blood groups; in the clinical laboratory, often called blood banking or transfusion services

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24
Q

immunology

A

the branch of medicine encompassing the study of the immune processes and immunity

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25
Q

Joint Commission (JC)

A

an independent agency that accredits hospitals and large healthcare facilities; formerly known as the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)

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26
Q

microbiology

A

the branch of biology dealing with microbes

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27
Q

mycology

A

the study of fungi

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28
Q

National Committee for Clinical Laboratory Standards (NCCLS)

A

see Clinical and Laboratory Standards Institute (CLSI)

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29
Q

pathologist

A

a physician specially trained in the nature and cause of disease

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30
Q

phlebotomist

A

a healthcare worker trained in blood collection

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31
Q

physician office laboratory (POL)

A

small medical laboratory located within a physician office, group practice, or clinic

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32
Q

plasma

A

the liquid portion of blood in which the blood cells are suspended; the straw-colored liquid remaining after blood cells are removed from anticoagulated blood

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33
Q

point-of-care testing (POCT)

A

testing outside the traditional laboratory setting; also called bedside testing, off-site testing, near-patient testing or alternative-site testing

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34
Q

proficiency testing (PT)

A

a program in which a laboratory’s accuracy in performing analyses is evaluated at regular intervals and compared to the performance of similar laboratories

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35
Q

Provider-Performed Microscopy Procedure (PPMP)

A

a certificate category under CLIA ‘88 that permits a laboratory to perform waived tests and also permits specified practitioners to perform on-site microscopy procedures

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36
Q

quality assessment (QA)

A

in the laboratory, a program that monitors the total testing process with the aim of providing the highest-quality patient care

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37
Q

reference laboratory

A

an independent regional laboratory that offers routine and specialized testing services to hospitals and physicians

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38
Q

serology

A

the study of antigens and antibodies in serum using immunological methods; laboratory testing based on the immunological properties of serum

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39
Q

serum

A

the liquid portion obtained from blood that has been allowed to clot

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40
Q

standard operating procedure (SOP)

A

established procedure to be followed for a given operation or in a given situation with the purpose of ensuring that a procedure is always carried out correctly and in the same manner

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41
Q

virology

A

the study of viruses

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42
Q

waived test

A

a category of test defined under CLIA ‘88 as being simple to perform and having an insignificant risk for error

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43
Q

American Association of Medical Assistants (AAMA)

A

professional society and credentialing agency for medical assistants

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44
Q

American Medical Technologists (AMT)

A

professional society and credentialing agency for several categories of medical laboratory personnel

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45
Q

American Society for Clinical Laboratory Science (ASCLS)

A

professional society for clinical/medical laboratory personnel

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46
Q

American Society for Clinical Pathology (ASCP)

A

professional society for clinical/medical laboratory personnel and allied health personnel

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47
Q

American Society of Phlebotomy Technicians (ASPT)

A

professional society and credentialing agency for phlebotomists, as well as credentialing agency for specialty areas such as point-of-care technician

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48
Q

ASCP Board of Certification (ASCP BOC)

A

a separate body within the ASCP organizational structure, formed in 2009 by merging NCA with the ASCP BOR and providing certification for medical laboratory personnel

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49
Q

clinical laboratory science

A

the health profession concerned with performing laboratory analyses used in diagnosing and treating disease, as well as in maintaining good health; synonymous with medical laboratory science and medical (laboratory) technology

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50
Q

clinical laboratory scientist (CLS)

A

the NCA term for a professional who has a baccalaureate degree from an accredited college or university, has completed clinical training in an accredited clinical/medical laboratory science program, and has passed a national certifying examination; also called medical laboratory scientist (MLS) or medical technologist (MT)

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51
Q

clinical laboratory technician (CLT)

A

the NCA term for a professional who has completed a minimum of 2 years of specific training in an accredited clinical/medical laboratory technician program and has passed a national certifying examination; also called medical laboratory technician (MLT)

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52
Q

Commission on Accreditation of Allied Health Education Programs (CAAHEP)

A

agency that accredits educational programs for allied health personnel; formerly CAHEA

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53
Q

ethics

A

a system of conduct or behavior; rules of professional conduct

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54
Q

Health Insurance Portability and Accountability Act (HIPAA)

A

1996 act of Congress, a part in which guarantees protection of privacy of an individual’s health information

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55
Q

medical laboratory science

A

the health profession concerned with performing laboratory analyses used in diagnosing and treating disease, as well as in maintaining good health; synonymous with clinical laboratory science and medical (laboratory) technology

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56
Q

medical laboratory scientist (MLS)

A

a professional who has a baccalaureate degree from an accredited college or university, has completed clinical training in an accredited medical laboratory science program, and has passed a national certifying examination; synonymous with medical technologist (MT) or NCA certified clinical laboratory scientist (CLS)

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57
Q

medical laboratory technician (MLT)

A

a professional how has completed a minimum of 2 years of specific training in an accredited medical laboratory technician program and has passed a national certifying examination; synonymous with NCA certified clinical laboratory technician (CLT)

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58
Q

medical technologist (MT)

A

a term gradually being replaced but referring to the professions of medical laboratory scientist (MLS) or clinical laboratory scientist (CLS)

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59
Q

medical technology

A

synonymous for clinical laboratory science and medical laboratory science

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60
Q

National Accrediting Agency for Clinical Laboratory Sciences (NAACLS)

A

agency that accredits educational programs for clinical laboratory personnel

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61
Q

National Credentialing Agency for Laboratory Personnel (NCA)

A

a credentialing agency for clinical laboratory personnel that merged with the ASCP Board of Registry (BOR) in 2009 to form the ASCP Board of Certification (BOC)

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62
Q

National Phlebotomy Association (NPA)

A

professional society and credentialing agency for phlebotomists

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63
Q

acquired immunodeficiency syndrome (AIDS)

A

a form of severe immunodeficiency caused by infection with the human immunodeficiency virus (HIV)

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64
Q

aerosol

A

liquid in the form of a very fine mist

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65
Q

alimentary tract

A

the digestive tube from the mouth to the anus

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66
Q

antiseptic

A

a chemical used on living tissues to control the growth of infectious agents

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67
Q

biohazard

A

risk or hazard to health or the environment from biological agents

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68
Q

biological safety cabinet

A

a special work cabinet that provides protection to the worker while working with infectious microorganisms

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69
Q

bloodborne pathogens (BBP)

A

pathogens that ban be present in human blood (and blood-contaminated body fluids)

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70
Q

Bloodborne Pathogens (BBP) Standard

A

OSHA guidelines for preventing occupational exposure to pathogens present in human blood and body fluids, including, but not limited to, HIV and hepatitis B virus (HBV); final OSHA standard of December 6, 1991, effective March 6, 1992

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71
Q

community-acquired infection (CAI)

A

infection acquired through contact with friends, family, and the public or by contact with contaminated environmental surfaces

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72
Q

disinfectant

A

a chemical used on inanimate objects to kill or inactivate microbes

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73
Q

engineering control

A

use of available technology and equipment to protect the worker from hazards

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74
Q

exposure control plan

A

a plan identifying employees at risk for exposure to bloodborne pathogens and providing training in methods to prevent exposure

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75
Q

exposure incident

A

an accident, such as a needlestick, in which an individual is exposed to possible infection through contact with body substances from another individual

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76
Q

hand antisepsis

A

decontamination of hands using antiseptic soap or waterless antiseptic handrub

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77
Q

hand hygiene

A

a set of techniques that includes handwashing with soap and water, washing with antiseptic soap, or cleansing with a waterless antiseptic product

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78
Q

healthcare-associated infection (HAI)

A

infection acquired while being treated for another condition in a healthcare setting; synonym for healthcare-acquired infection; formerly called nosocomial infection

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79
Q

hepatitis B virus (HBV)

A

the virus that causes hepatitis B infection and is transmitted by contact with infected blood or other body fluids

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80
Q

hepatitis C virus (HCV)

A

the virus that causes hepatitis C infection and is transmitted by contact with infected blood or other body fluids

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81
Q

human immunodeficiency virus (HIV)

A

the retrovirus that has been identified as the cause of AIDS

82
Q

isolation

A

the practice of limited the movement and social contact of a patient who is potentially infectious or who must be protected from exposure to infectious agents; quarantine

83
Q

other potentially infectious materials (OPIM)

A

any and all body fluids, tissues, organs, or other specimens from a human source

84
Q

parenteral

A

any route other than by the alimentary canal; intravenous, subcutaneous, intramuscular, or mucosal

85
Q

pathogenic

A

capable of causing damage or injury to the host

86
Q

personnel protective equipment (PPE)

A

specialized clothing or equipment used by workers to protect from direct exposure to blood or other potentially infectious or hazardous materials; includes, but is not limited to, gloves, laboratory apparel, eye protection, and breathing apparatus

87
Q

Standard Precautions

A

a set of comprehensive safety guidelines designed to protect patients and healthcare workers by requiring that all patients and all body fluids, body substances, organs, and unfixed tissues be regarded as potentially infectious

88
Q

sterilization

A

the act of eliminating all living microorganisms from an article or area

89
Q

Transmission-Based Precautions

A

specific safety practices used in addition to Standard Precautions when treating patients known to be or suspected of being infected with pathogens that can be spread by air, droplet, or contact

90
Q

Universal Precautions (UP)

A

a method of infection control in which all human blood and other body fluids containing visible blood are treated as if infectious

91
Q

work practice controls

A

methods of performing tasks that reduce the worker’s exposure to blood and other potentially hazardous materials

92
Q

autoclave

A

an instrument that uses pressurized steam for sterilization

93
Q

carcinogen

A

a substance with the potential to produce cancer in humans or animals

94
Q

caustic

A

a chemical substance having the ability to burn or destroy tissue

95
Q

centrifuge

A

instrument with a rotor that rotates at high speeds in a closed chamber

96
Q

chemical hygiene plan

A

comprehensive written safety plan detailing the proper use and storage of hazardous chemicals in the workplace

97
Q

fume hood

A

a device that draws contaminated air out of an area and either cleanses and recirculates it or discharges it to the outside

98
Q

material safety data sheet (MSDS)

A

written safety information that must be supplied by manufacturers of chemicals and hazardous materials

99
Q

mutagen

A

a substance or agent, such as radiation, certain chemicals, or some viruses, that causes a stable change in a gene that can then be passed on to offspring

100
Q

National Institute for Occupational Safety and Health (NIOSH)

A

federal agency responsible for workplace safety research and that makes recommendations for preventing work-related illness and injury

101
Q

Occupational Safety and Health Act (OSH Act)

A

congressional act of 1970 created to help reduce on-the-job illnesses, injuries, and deaths requiring employers to provide safe working conditions

102
Q

Occupational Safety and Health Administration (OSHA)

A

the federal agency that creates workplace safety regulations and enforces the Occupational Safety and Health Act of 1970

103
Q

personal protective equipment (PPE)

A

specialized clothing or equipment used by workers to protect from direct exposure to blood or other potentially infectious or hazardous materials

104
Q

radioisotope

A

an unstable form of an element that emits radiation and can be incorporated into diagnostic tests, medical therapies, and biomedical research; radioactive isotope

105
Q

teratogen

A

a substance or agent capable of causing birth defects by direct harm to a fetus or embryo, or by interfering with normal fetal development

106
Q

autoclave

A

a device that uses pressurized steam for sterilization

107
Q

beaker

A

a wide-mouthed, straight-sided container with a pouring spout formed from the rim and used to make measurements

108
Q

borosilicate glass

A

nonreactive glass with high thermal resistance commonly used to make high-quality labware

109
Q

centrifuge

A

an instrument with a rotor that rotates at high speeds in a closed chamber

110
Q

critical measurements

A

measurements made with the accuracy of the concentration of a solution is important; measurements made using glassware manufactured to strict standards

111
Q

flask

A

a container with an enlarged body and a narrow neck

112
Q

flint glass

A

inexpensive glass with low resistance to heat and chemicals

113
Q

graduated cylinder

A

an upright, straight-sided container with a flared base and a volume scale

114
Q

labware

A

article(s) or container(s) intended for laboratory use

115
Q

meniscus

A

the curved upper surface of a liquid in a container

116
Q

microfuge

A

a centrifuge that spins microcentrifuge tubes at high rates of speed; microcentrifuge

117
Q

National Institute for Standards and Technology (NIST)

A

a federal agency that promotes international standardization of measurements; formerly the National Bureau of Standards

118
Q

noncritical measurements

A

estimated measurements; measurements made in containers that estimate volume (such as beakers)

119
Q

pH

A

a measurement of the hydrogen ion concentration expressing the degree of acidity or alkalinity of a solution

120
Q

pipet

A

a slender calibrated tube used for measuring and transferring liquids

121
Q

polyethylene

A

plastic polymer of ethylene used for containers

122
Q

polypropylene

A

lightweight plastic polymer that resists moisture and solvents and withstands heat sterilization

123
Q

polystyrene

A

clear, colorless polymer of styrene used for labware

124
Q

quartz glass

A

expensive glass with excellent light transmission; glass used for cuvettes; silica glass

125
Q

reagent

A

substance or solution used in laboratory analyses; substance involved in a chemical reaction

126
Q

rotor

A

the part of a centrifuge that holds the tubes and rotates during the operation of the centrifuge

127
Q

serological centrifuge

A

a centrifuge that holds the tubes such as those used in blood banking; serofuge

128
Q

solute

A

the substance dissolved in a given solution

129
Q

solvent

A

a dissolving agent, usually a liquid

130
Q

tare

A

in chemical analysis, a determination of the net weight of a chemical by subtracting the weight of the container from the overall weight of the container and the chemical being weighed

131
Q

Celsius (C) scale

A

temperature scale having the freezing point of water at 0 degrees C and the boiling point at 100 degrees C

132
Q

centi-

A

prefix used to indicate one-hundredth (10^-2) of a unit

133
Q

Clinical and Laboratory Standards Institute (CLSI)

A

an international institute composed of representatives from government, industry, and patient-testing professions that develops and publishes standards and guidelines for regulatory agencies and accrediting bodies; formerly the National Committee for Clinical and Laboratory Standards (NCCLS)

134
Q

deci-

A

prefix used to indicate one-tenth (10^-1) of a unit

135
Q

English system of measurement

A

system of measurement in common use in the United States for nonscientific measurement; sometimes called the US customary system

136
Q

Fahrenheit (F) scale

A

temperature scale having a freezing point of water at 32 degrees F and boiling point at 212 degrees F

137
Q

femto-

A

prefix used to indicate 10^-15

138
Q

gram (g)

A

basic metric unit of weight or mass

139
Q

kilo-

A

prefix used to indicate 1000 (10^3) units

140
Q

liter (L)

A

basic metric unit of volume

141
Q

meter (m)

A

basic metric unit of length or distance

142
Q

metric system

A

the decimal system of measurement used internationally for scientific work

143
Q

micro-

A

prefix used to indicate one-millionth (10^-6) of a unit

144
Q

milli-

A

prefix used to indicate one-thousandth (10^-3) of a unit

145
Q

nano-

A

prefix used to indicate one-billionth (10^-9) of a unit

146
Q

National Institute of Standards and Technology (NIST)

A

a federal agency that promotes international standardization of measurements; formerly the National Bureau of Standards

147
Q

pico-

A

prefix used to indicate 10^-12 of a unit

148
Q

SI units

A

standardized units of measure; international units

149
Q

Beral pipet

A

a disposable plastic pipet with a built-in bulb on one end that usually can deliver up to 2 mL and can have a graduated stem; also called a transfer pipet

150
Q

deionized water

A

water that has had most of the mineral ions removed

151
Q

diluent

A

a liquid added to a solution to make it less concentrated

152
Q

dilution

A

a solution made less concentrated by adding a diluent; the act of making a dilute solution; the degree to which a solution is made less concentrated

153
Q

dilution factor

A

reciprocal of the dilution

154
Q

distilled water

A

the condensate collected from steam after water has been boiled

155
Q

formula weight (F.W.)

A

the sum of the atomic weights of the atoms in a compound; molecular weight

156
Q

gram equivalent weight

A

the number obtained by dividing the formula weight by the valence

157
Q

lyophilize(d)

A

remove water from a frozen solution under vacuum; freeze-dry

158
Q

micropipet

A

a pipet that measures or holds 1 milliliter or less

159
Q

micropipetter

A

a mechanical pipetter that can measure or deliver very small volumes, usually 1 mL or less

160
Q

molar solution (M)

A

solution containing 1 mole of solute per liter of solution

161
Q

mole

A

formula weight of a substance expressed in grams

162
Q

molecular weight (M.W.)

A

the sum of the atomic weights of the atoms in a molecule or compound; formula weight

163
Q

normality (N)

A

the number of gram equivalents of a compound per liter of solution

164
Q

percent solution

A

a solution made by adding units of solute per 100 units of total solution

165
Q

physiological saline

A

0.85% (0.85 M) sodium chloride solution

166
Q

pipet

A

a slender calibrated tube used for measuring and transferring liquids

167
Q

proportion

A

relationship in number or amount of one portion compared to another portion or to the whole; ratio

168
Q

ratio

A

relationship in number or degree between two things

169
Q

reagent

A

substance of solution used in laboratory analyses; substance involved in a chemical reaction

170
Q

reverse osmosis

A

purification of water by forcing water under high pressure through a semi-permeable membrane

171
Q

solute

A

the substance dissolved in a given solution

172
Q

solution

A

a homogeneous mixture of two or more substances

173
Q

solvent

A

a dissolving agent, usually a liquid

174
Q

TC

A

on pipets, a mark indicating “to contain”

175
Q

TD

A

on pipets, a mark indicating “to deliver”

176
Q

titer

A

in serology, the reciprocal of the highest dilution that gives the desired reaction; the concentration of a substance, determined by titration

177
Q

valence

A

the positive or negative charge of a molecule; a number representing the combining power of an atom

178
Q

accuracy

A

the closeness of agreement of a measured value with the true value

179
Q

average

A

the sum of a set of values divided by the number of values in the set; the mean

180
Q

blind sample

A

an assayed sample that is provided as an unknown to laboratories participating in proficiency testing programs

181
Q

calibration

A

the process of checking, standardizing, or adjusting a method or instrument so that it yields accurate results

182
Q

coefficient of variation (CV)

A

a calculated value that compares the relative variability between different sets of data

183
Q

controls

A

commercially available assayed solutions that are chemically and physically similar to the unknown and are tested in the same manner as the unknown to monitor the precision of a test method

184
Q

Gaussian curve

A

a graph plotting the distribution of values around the mean; normal frequency curve

185
Q

Levey-Jennings chart

A

a quality control chart used to record daily quality control values

186
Q

mean

A

the sum of a set of values divided by the number of values in the set; the average

187
Q

population

A

the entire group of items or individuals from which the samples under consideration are presumed to have come

188
Q

precision

A

reproducibility of results; the closeness of obtained values to each other

189
Q

quality assessment (QA)

A

in the laboratory, a program that monitors the total testing process with the aim of providing the highest quality patient care; formerly called quality assurance

190
Q

quality control (QC)

A

a system that verifies the reliability of analytical test results through the use of standards, controls, and statistical analysis

191
Q

quality systems (QS)

A

in an institution, a comprehensive program in which all areas of operation are monitored to ensure quality with the aim of providing the highest quality patient care

192
Q

random error

A

error that is inconsistent and whose source cannot be definitely identified

193
Q

sample

A

in statistics, a subgroup of a population

194
Q

shift

A

an abrupt change from the established mean indicated by the occurrence of all control values on one side of the mean

195
Q

standard

A

a chemical solution of a known concentration that can be used as a reference or calibration substance

196
Q

standard deviation (s)

A

a measure of the spread of a population of values around the mean

197
Q

statistics

A

the branch of mathematics that deals with the collection, classification, analysis, and interpretation of numerical data; a collection of quantitative data

198
Q

systematic error

A

error that is introduced into a test system and is not a random occurrence

199
Q

trend

A

an indication of error in the analysis, detected by a progressive drift of control values in one direction for at least 5 consecutive runs

200
Q

variance (s^2)

A

the square of the standard deviation; mean square deviation

201
Q

Westgard’s rules

A

a set of rules used to determine when a method is out of control