Unit 1: Chapter 3: Flashcards

1
Q

What are the structures of the cell, and what are their functions?

A

1) Cell membrane (Sarcolmma in skeletal muscle)
— Separates cell from environment

2) Nucleus
— Contains genes that regulate protein synthesis
—contains genetic info

3) Cytoplasm (Sarcoplasm)
—Fluid
—Contains organelles
—Mitochondria

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2
Q

Metabolism

A

The sum of all chemical reactions that occur in the body

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3
Q

Metabolic Reactions:
Anabolic vs. Catabolic reactions
Which are Endergonic and Exergonic?

A

Anabolic reaction — Synthesis of molecules—(Endergonic)

Catabolic reaction —Breakdown of molecules—(Exergonic)

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4
Q

Bioenergetic

A

Process of converting food to energy

(You can guess what the metabolism through oxygen consumption — How you burn calories )

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5
Q

Coupled Reactions

A

Energy in an exergonic reaction drives an endergonic reaction.

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6
Q

Why do we release energy a little bit at a time instead of all at once?

A

So we don’t damage the cells.

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7
Q

Oxidation + Reduction

A

Oxidation—Removing an electron or Hydrogen (remove — charge)

Reduction— Addition of an electron or Hydrogen (+)
(Or water)

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8
Q

Oxidation and reaction are always ___ reactions.

A

Coupled reactions

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9
Q

Two most important carrier molecules in electron transport?
What do they do?

A

NAD and FAD— Transfer electrons during bioenergetic reactions

1) Nicotinamide adenine dinucleotide (NAD)
—Oxidized from: NAD+
—Reduced from of NAD: NADH

2)Flavin adenine dinucleotide (FAD)
—Oxidized form of FAD: FAD
—Reduced form: FADH2

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10
Q

what are Enzyme? What do they do to the speed of reactions?

A

Enzyme—Cellular proteins that catalyze reactions.

They speed up reactions by Lower the energy of activation

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11
Q

What are factors that regulate enzyme activity?

A

1) Temperature
—Because temp. increases enzyme activity. And if it is a large temp increase, it could denature (uwind) them.

2) pH
—Any change to pH can decrease Enzyme activity
—Creates acid

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12
Q

Which type of reactions can Enzyme-catalyze?
What do they interact with?
What type of rections can they do and do it to?

A

They can catalyze any type of reaction; All proteins
Substrates (Locke and key theory);
Catablic or Anabolic

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13
Q

Kinases

A

Adds a phosphate to a reaction

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14
Q

Dehydrogenases

A

Remove hydrogen

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15
Q

Oxidases

A

Cataylze oxidation-reduction reactions involving oxygen

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16
Q

Isomerases

A

Rearrangment of the structure of molecules

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17
Q

____ Levels in the blood serve as biomarkers of disease ot tissue damage

A

Enzyme

18
Q

Elevated lactate dehydrogenase or creatine kinase in the blood by indicate a ____

A

myocardial infarction

19
Q

List THREE forms in which the human body stores energy

A

Carbohydrates, Fats, and protien

20
Q

List in order major energy systems; calorie range and distance?

A

ATP–(1)–(17.5 yards)
PCr—(4)—70 yards)
Carbs—(20-1,500)—(150 yards-15 Miles)
Fat—(7-80,000)—(123 yards-800 miles)
Protien—(30,000)—(300 miles)

21
Q

ATP can be thought of as the body’s “energy currency,” ATP stands for:

A

Adenosine Triphosphate

22
Q

What is glucose?

A

Glucose–blood sugar

23
Q

What are lipid droplets of fat?

A

Triglcoride
Glycerol
Free Fatty Acid

24
Q

What is Glycogen? What is it made of? Where is it stored?

A

Glycogen—The storage form of glucose

Made: Polysaccharide, Glucose

Stored in: Liver, Skeletal Muscle

25
Q

What is Glcogenolysis?

A

break down of glycogen to glucose

(By Enzyme Glycogen Synthase)

26
Q

What are fatty acids? How and where is it stored? How os it broken down?

A

Store it as triglycerides in fat or muscle;

Broken down into glycerol and fatty acids by lipolysis.

27
Q

What are proteins made of? How are they used as an energy scource?

A

**chain of Amino Acids (AA) **
(converted to glucose in the liver) == Gluconeogensis
or
converted to metablic intermediates (TCA) == fuel in muscle

28
Q

What are the different ways ATP forms?

A

Anaerobic pathways: No O2
1) PC Breakdown
2) Glycolisis (dehydration of glucose and glycogen)
3) Oxidative formation of ATP

Aerobic Pathways: NEEDS O2
1) Oxidative phosporylation

29
Q

What is teh enzyme of teh phosphate system?

A

creatine Kinase

30
Q

What is the ATP—PC System? When is it used? When does it recharge? How many enzymatic reactions occur and which Enzyme does it use?

A

ATP-PC System// Phosphagen System—Rapid source of energy because it uses stored ATP (Anaerobic);

At the beginning of ALL activities,

replenishes it every 8 mins;

Few Enzymatic reactions; creatine kinase

31
Q

Glycolysis is a ___ reaction.

A

Coupled Reaction

32
Q

Where does ATP-PC System take place?

A

Takes place outside the mitochondria;
In the sarcoplasm

33
Q

What does Creatine kinase do?

A

catalyzes the breakdown of PC
synthesis ATP

34
Q

What are the two phases of Glycolysis? What major event happens in each?

A

1) Energy investment phase
—Glucose converted
—2 ATP required

2) Energy generation/ harvest phase
—4 ATP produced
—2 NADH
—2 pyruvate / lactatete

35
Q

What is fast Glycolysis?

A

Anaerobic glycolysis
— Converts pyruvate to lactate
—gain 2-3 ATP
—oxy (30-120 secs)
—High-intensity exercise

36
Q

What is Slow Glycolysis?

A

Aerobic glycolysis
—Shuttles pyruvate to mitochondria
—Kerba Cycle
—Lower-intensity exercise
—32 ATP per glucose!

37
Q

What is the Cori Cycle?

A

When lactate is transported in the blood liver to be converted to glucose

38
Q

Is lactate the cause of fatigue?

A

NO

39
Q

What enzyme catalyzes lacted from pyruvate?

A

Lactate dehydrogenase

40
Q

Define rate-limiting enzymes

A

An enzyme that regulates the speed of a metabolic pathway

41
Q

What are the modulators of rate-limiting enzymes?

A

1) Levels of ATP and ADP+P
(Too high = limit ATP production; too low = stimulate ATP production)

2) Calcium Stimulates aerobic ATP production

42
Q
A