Unique fraction of the human genome Flashcards
1
Q
Are all human genes the same size?
A
Nope. Range from some tRNA genes that are less than 100 bp to dystrophin that is 2.5 million base pairs
2
Q
What is the relationship between exonic contribution and gene size?
A
Negative linear relationship. The larger the gene, the less exonic contribution
3
Q
What is exonic contribution?
A
How much of a gene is actually coding the protein
4
Q
Are human genes equally spread across the genome?
A
Nope
5
Q
Which regions of the genome are most genes located?
A
G/C rich regions (R-bands), and subtelomeric regions
6
Q
Which regions of the genome have low gene density?
A
Centromeric regions and A/T rich regions (G-bands)